This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
B.Pharm. (Second Semester) (C.B.S.) Examination
PHARMACEUTICAL CHEMISTRY—II (Organic)
Paper-2 (2 T 2)
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Time : Three Hours] [Full Marks: 80
N.B. :— (1) Question No. 1 is compulsory.
(2) Solve any FOUR questions from the remaining.
(3) Draw neat labelled diagram wherever necessary.
(4) Discuss the reaction, mechanism wherever necessary.
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(5) Use of electronic calculator is permitted.
- Solve any FIVE of the following : 5×4=20
- Define stereoisomers giving examples.
- Give sources of organic compounds with examples.
- Explain various intermolecular forces.
- Why chair conformation is more stable than the boat conformation in cyclohexane ?
- What is hybrid orbital ? Explain hybridisation.
- Write the principle involved in detection and estimation of elemental nitrogen in organic compounds.
- Melting point of inorganic compounds is more than that of organic compounds.
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- (a) Write in detail about the Kjeldahl's method of Nitrogen estimation. 7
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(b) What are racemic mixtures ? Explain various methods of resolution of racemic mixtures. 8 - (a) Define the term functional group. Enlist the various functional groups present in the organic compounds and write in brief about the types of organic reactions. 7
(b) Define the term empirical formula and molecular formula. Give the various rules for calculating the empirical formula. 3
(c) A qualitative analysis of papaverine, one of the alkaloids in opium showed carbon, hydrogen and nitrogen. A qualitative analysis gave 70.8% carbon, 6.2% hydrogen and 4.1% nitrogen. Calculate the empirical formula of papaverine. 5 - (a) Define the term conformation. Write in detail about the conformation of n-butane with energy profile diagram. 7
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(b) Justify the following statements :
(i) Trans-isomers are more stable than cis isomers.
(ii) Salicylic acid is stronger than p-hydroxy benzoic acid. 8 - (a) Give brief account on hydrogen bonding and explain its effect on aqueous solubility and bond lengths. 8
(b) What is an orbital ? Give an account on atomic orbital and molecular orbital theory. 7 - (a) Write in detail about the structure of cyclohexane and the conformation of substituted cyclohexane. 7
(b) Give the IUPAC name of the following :
(i) ΗΗΗΗ H-С С С с-н HHOH H
(ii) H3C – C – C = CH
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CH3
(iii) CH3-C – CH3
OH
(c) Write short note on Bayer's Strain theory. 4 - (a) Define and classify alcohols with suitable examples. How will you differentiate primary, secondary and tertiary alcohols. 7
(b) Draw structure of the following compounds :
(i) 1, 2-Dibromopropane
(ii) 3-methyl octane
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(iv) β-naphthol.
(c) Write a note on sequence rule. 4
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University