Download RTMNU B.Pharma 2nd Semester 2017 Winter Pharmaceutical Chemistry 2 (Organic) Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 2nd Semester 2017 Winter Pharmaceutical Chemistry 2 (Organic) Question Paper

NRJ/KW/17/4262
B.Pharm. Semester-II (C.B.S.) Examination
PHARMACEUTICAL CHEMISTRY?II (ORGANIC)
Paper?Z
Time : Three Hours] [Maximum Marks : 80
NB. :? (1) Question No. 1 is compulsory.
(2) Solve any FOUR questions from remaining.
(3) Draw neat labelled diagram wherever necessary.
(4) Discuss the reaction, mechanism wherever necessary.
(5) Use of electronic calculator is permitted.
1. Solve any FIVE of the following :
(a)
(b)
(C)
(d)
(e)
(f)
(g)
2. (a)
(b)
3. (a)
(b)
4. (a)
(b)
Write in brief about the Quantum structure of atom.
Differentiate between Organic and Inorganic compounds.
De?ne the term bond. Give the various types of bonds and write in brief about covalent bond.
Give the scope of organic chemistry with examples.
Give the classi?cation of dienes along with examples.
Give the properties and uses of alkyl halides.
De?ne the term functional group and give the various types of organic reactions. 5X4=20
Explain in detail about the combustion method of carbon and hydrogen estimation. 8
0.2475 g of organic compound gives 0.4950 g of carbon dioxide and 0.2025 g of water.
Calculate the percentage of carbon and hydrogen in it. 7
De?ne the tenn isomerism and give its classi?cation. Write in detail about R and S system of
nomenclature with special emphasis on sequence rule. 8
Write in detail about the acidity of carboxylic acids and phenols. 7
De?ne the term Empirical formula and molecular formula. Give the various rules for calculating
the empirical formula.
An organic compound has found to possess empirical formula CHZO and molecular weight is 90.
Find the molecular formula. 8
Write in detail about the structure of cyclohexane and the conformation of substituted cyclohexane.
7
5. Write notes on any three of the following :
(a)
(b)
(C)
(d)
6. (a)
(b)
(C)
7. (a)
(b)
Bayer strain theory
Lucas test for alcohol
Principle of sodium extract method
Hinsberg's test for amines. 5X3=15
Why the melting point of inorganic compounds is more than that of organic compounds ? Explain
with example.
Why alcohol is called as co?solvent ? Also explain about the solubility of water in methanol but
not with carbon tetrachloride.
Why para hydroxy benzoic acid is less acidic than benzoic acid and salicylic acid is 15 times
more acidic than benzoic acid ? 5X3=15
Draw the structural formula and give IUPAC name of the following :
(i) CH3 CH2 CO CH2 CH2 CO CH (CH3)2
(ii) Cyclohexadiene
(iii) trans (CH3)2CH CH=CH CH (CH3)2
(iv) (CHQZCH CH.0 CH. CH (CHQZ 8
Write in brief about the Newman projection formula and give detail account of conformation of
ethane with energy pro?le diagram. 7
POY?25680