Download RTMNU B.Pharma 3rd Semester 2015 Winter Pharmacology 1 Question Paper

NTK/KW/15/6984

Faculty of Pharmacy

B.Pharm. Third Semester (C.B.S.) Examination

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PHARMACOLOGY—?

Paper-IV

Time : Three Hours] [Full Marks: 80

N.B. :— (1) Question No. 1 is compulsory.

(2) Solve any FOUR questions from the remaining.

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(3) Draw neat labeled diagram wherever necessary.

1. Solve any FIVE :
   1. Discuss various mechanisms of drug transport across cell membrane. 4
   2. How does bioavailability affect pharmacokinetics ? 4
   3. What is agonist, inverse agonist, and competitive and non-competitive antagonist ? 4
   4. Discuss pharmacological activities of Atropine. 4

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   5. Mention location and biological actions mediated by muscarinic receptors. 4
   6. Discuss the mechanism of amphetamine as stimulant. 4
   7. Enumerate pharmacological properties of physostigmine. 4
2. 1. Discuss the pharmacological actions of ß adrenergicom blockers. Explain the mechanism, pharmacological actions and side effects of pilocarpine. 10

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   2. Discuss the pharmacology of drugs used in glaucoma. 5
3. 1. Discuss the pharmacological actions of Sympathomimetics with special emphasis on dopamine. 10
   2. Discuss pharmacology of pseudoephedrine. 5

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4. 1. Explain the mechanism of different allergic reactions. Discuss idiosyncrasy with example. 8
   2. Explain the drug-receptor interactions with suitable examples. 7
5. 1. Discuss various factors affecting drug absorption in detail. How does protein binding affect excretion of drugs ? 8
   2. Discuss the factors affecting excretion of drugs. Comment on physiological barriers. 7

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6. 1. Discuss the pharmacological details of Tertiary amines. 7
   2. Discuss various competitive ganglionic blockers with special emphasis on hexamethonium. 8
7. Short notes (any two) :
   1. Types of Bioassay

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   2. Drug metabolism
   3. Nicotine.

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