Download RTMNU B.Pharma 3rd Semester 2016 Summer Pharmaceutical Chemistry 3 (Organic) Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 3rd Semester 2016 Summer Pharmaceutical Chemistry 3 (Organic) Question Paper

TKN/KS/16 ?6982
Third Semester Examination For the
Degree 01? Bachelor of Pharmacy
PHARMACEUTICAL CHEMISTRY ? 111
(ORGANIC)
3?T?2
Time : Three Hours] [MaX. Marks : 80
N. B. :(1) Question No.1 is Compulsory.
(2) Solve any Four questions from the remaining.
(3) Discuss the reaction, mechanism wherever
necessary.
1. Solve any Five of the following :?
(a) Write a note on Keto-enol tautomerism
(b) Explain Huckel?s Rule.
(0) Differentiate between SNl and SN2.
(d) Aldehydes are more reactive than Ketone, Explain.
(e) Explain Con?rmations 0f n?butane.
(1) Write the mechanism of Hofmann degradation
reaction.
(g) State and explain any two reactions of phenol.
5 X 4 = 20
2. Discuss the electrophilic aromatic substitution reaction
of benzene with :?
(a) Nitration
(b) Sulphonation
TKN/KS/16 ? 6982 Contd.
(c) Halogenation
(d) Friedel-Cra??s alkylation
(e) Friedel?Craft?s acylation 15
3. Give the detail account of SN2 including reaction,
mechanism, orientation and reactivity. 15
4. Write a Concise account on reactions and preparations
of Carboxylic acids. 15
5. Prepare a full length draft on biomolecular elimination
reaction covering mechanism, evidences, orientation and
stereochemistry with appropriate examples. 15
6. (a) Describe in detail on preparation of alkenes using
suitable examples. 8
(b) Discuss about acidity of Carboxylic acids. 7
7. Write notes on (Any Three) :?
(a) Aldol condensation.
(b) Connizarro?s Reaction
(0) Structure of benzene
(d) Hinsberg test
(e) Synthesis and applications of Organometallic
Compounds. 15
TKN/KS/16? 6982 2 530