Download RTMNU B.Pharma 3rd Semester 2017 Summer Pharmacology 1 Question Paper

Download RTMNU (Rashtrasant Tukadoji Maharaj Nagpur University) B.Pharma (Bachelor of Pharmacy) 3rd Semester 2017 Summer Pharmacology 1 Question Paper

NKT/KS/l 7/6555
B.Pharm. Semester?III (C.B.S.) Examination
PHARMACOLOGY?I
Paper?4
Time : Three Hours] [Maximum Marks : 80
Note :?(1) Question No. 1 is compulsory.
(2) Solve any four questions from the remaining.
(3) Draw neat labelled diagrams wherever necessary.
1. Solve any ?ve :
(21) Compare the pharmacological pro?le of neostigmine and physostigmine.
(b) Explain the signi?cance of plasma protein binding with suitable examples.
(0) Write principle and methodology of insulin bioassay.
(d) Describe the symptoms and treatment of myastania gravis.
(e) Justify the use of adrenorgic agonists in the treatment of bronchial asthma.
(1) What is log-dose response curve ? Explain its signi?canse.
(g) Write a brief note on nuclear receptors. 5X4=20
2. Give classi?cation of anti?cholinergic agents. Explain phaImacological pro?le, clinical indication and
adverse effect of anti?muscarinic agents. 15
3. Explain mechanism of action, pharmacokinetic adverse effects, contraindication and therapeutic uses
of propranolol. 15
4. Explain different routes of drug administration along with advantages and drawbacks. Add a note on
Enema. 15
5. What is ?rst pass metabolism ? Explain in detail various phases of drug metabolism. Add a note on
microsomal enzyme induction and inhibition. 15
6. Give classi?cation and explain mechanism of action, pharmacokinetic, adverse effects and clinical
indications of Anti?cholinesterases agents. 15
NXO?12537 1 (C0ntd.)

7. Write short notes on the following (any three) :
(a) Neuromuscular stimulant drugs
(b) Excretion of drugs
(0) Factors affecting drug absorption
(d) Principle and design of digitalis bio?assay. 3X5=15
NXO?12537 2 NKT/KS/17/6555