This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University
NKT/KS/17/6555
B.Pharm. Semester—III (C.B.S.) Examination
PHARMACOLOGY-I
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Paper-4
Note :- (1) Question No. 1 is compulsory.
(2) Solve any four questions from the remaining.
(3) Draw neat labelled diagrams wherever necessary.
[Maximum Marks : 80
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Solve any five :
- Compare the pharmacological profile of neostigmine and physostigmine.
- Explain the significance of plasma protein binding with suitable examples.
- Write principle and methodology of insulin bioassay.
- Describe the symptoms and treatment of myastania gravis.
- Justify the use of adrenergic agonists in the treatment of bronchial asthma.
- What is log-dose response curve ? Explain its significance.
- Write a brief note on nuclear receptors.
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5×4=20
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Give classification of anti-cholinergic agents. Explain pharmacological profile, clinical indication and adverse effect of anti-muscarinic agent.
15
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Explain mechanism of action, pharmacokinetic adverse effects, contraindication and therapeutic uses of propranolol.
15
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Explain different routes of drug administration along with advantages and drawbacks. Add a note on Enema.
15
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What is first pass metabolism ? Explain in detail various phases of drug metabolism. Add a note on microsomal enzyme induction and inhibition.
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15
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Give classification and explain mechanism of action, pharmacokinetic, adverse effects and clinical indications of Anti-cholinesterases agents.
15
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Write short notes on the following (any three) :
- Neuromuscular stimulant drugs
- Excretion of drugs
- Factors affecting drug absorption
- Principle and design of digitalis bio-assay.
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3×5=15
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This download link is referred from the post: RTMNU B-Pharm Last 10 Years 2010-2020 Previous Question Papers || Rashtrasant Tukadoji Maharaj Nagpur University