Download RTMNU B.Pharma 4th Semester 2015 Winter Pharmaceutical Chemistry 4 (Heterocyclic And Macromolecules) Question Paper

NTK/KW/15 – 6988

Fourth Semester Examination for the Degree of Bachelor of Pharmacy

PHARMACEUTICAL CHEMISTRY-IV

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Heterocyclic and Macromolecules

Paper 4T2

Time: Three Hours ] [Max. Marks: 80

N. B. : (1) Question No. 1 is Compulsory.

(2) Solve any four questions from the remaining.

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(3) Draw neat labeled diagram wherever necessary.

1. Comments on the following (any five) :-
   1. Importance of heterocycles in Pharmaceutical Sciences.
   2. Interconversion of glucose to fructose.
   3. Cyclic structure of monosaccharides.
   4. Synthesis of Alpha amino acids.

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   5. Pschorr synthesis of phenanthrene.
   6. Pyridine is a stronger base than pyrrole.
   7. Saponification value of fats.

   5x4=20

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2. Give preparation, properties and uses of the following:
   1. Imidazole.
   2. Pyridine.
   3. Furan.

   15

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3. Discuss synthesis, properties and biological importance of Quinoline and purine.

   15

4. 1. Give synthesis and important properties of Naphthalene.

      8

   2. Discuss various characteristic values used to identify and detect adulteration in fixed oils and fats.

      7

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5. 1. Discuss structural elucidation of sucrose as disaccharide.

      8

   2. Explain oxidative reactions in monosaccharide.

      7

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6. 1. Define and classify amino acids with suitable structures.

      8

   2. Discuss various methods for synthesis of polypeptides.

      7

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7. 1. Write short notes on (any three) :—
      1. Mutarotation.
      2. Epimerization.
      3. Phospholipids.

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      4. Glycosides.

      3x5=15

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