Download RTMNU B.Pharma 4th Semester 2015 Winter Pharmacology 2 Question Paper

NTK/KW/15 – 6990

Fourth Semester Examination for the Degree of Bachelor of Pharmacy

PHARMACOLOGY–II

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Paper - 4.4

Time: Three Hours ] [Max. Marks: 80

N. B.: (1) Question No. 1 is Compulsory.

(2) Solve any four questions from the remaining.

(3) Draw neat labeled diagram wherever necessary.

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1. Solve any five :-
   1. Aspirin in Rheumatoid arthritis.
   2. Epinephrine in hypovolemic shock.
   3. Cinnarizine in vertigo.
   4. Ezetimibe as hyperlipidemic drugs.
   5. Clinical uses of prostaglandins.

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   6. Phosphodiesterase III inhibitors.
   7. Antifibrinolytic agents. 4x5=20
2. (a) Classify antihypertensive drugs. Explain pharmacology of ACE inhibitors in detail. 10
   (b) Discuss various pharmacological approaches to treat angina pectoris. 5

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3. (a) Describe in detail synthesis, storage and destruction of serotonin. Give mechanism, uses and adverse effects of any two 5-HT antagonists. 10
   (b) Write a note on platelet activating factor. 5
4. (a) Give classification of NSAIDs. Explain the mechanism, adverse effects and uses of :
   1. Oxicam derivatives.
   2. Coxibs. 10
   (b) Explain potassium channel openers. 5

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5. (a) Discuss antiarrhythmic drugs. 10
   (b) Comment on H₁ antihistaminic drugs. 5
6. (a) Discuss pathophysiology of congestive heart failure. Explain in detail about digitalis. 10
   (b) Give detailed account on antiplatelet agents. 5
7. Give short note on any two :—
   1. Thiazide diuretics.

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   2. Anti coagulants.
   3. Histamine receptors. 15

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