Download OU M.Pharma Pharmaceutics 1st Sem 2018 1291PCI Modern Pharmaceutics Question Paper

Download OU (Osmania University) M.Pharma-Pharmaceutics (Master of Pharmacy) 1st Sem 2018 1291PCI Modern Pharmaceutics Previous Question Paper

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Code No. 1291/PCI
FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutics) I-Semester (PCI) (Suppl.) Examination, August 2018
Subject: Modern Pharmaceutics
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 (a) Explain the methods for testing of drug excipient compatability studies. 6
(b) Describe the preparation of SMEDDS and their evaluation tests. 6
(c) Define factorial design. Describe the applications and limitations. 3
2 (a) Discuss the ICH guidelines for calibration and validation of equipment with an
example. 8
(b) Describe the validation of tableting process. 7
3 (a) Discuss the sales forecasting and budget planning in pharmaceutical industries. 8
(b) Describe the layt of buildings, services, equipment and their maintenance in
industries. 7
4 (a) What is compaction profile? Explain the phases of compaction profile with a
suitable examples. 5
(b) Define the term intrinsic solubility. How to determine ? it?s significance? 5
(c) Explain the properties of granules effecting the compression behavior of tablets.5
5 (a) Discuss the pharmacokinetic parameters for determination of bioavailability. 5
(b)Describe the comparison of dissolution profiles of dosage forms using similarity
and difference factors. 5
(c) Explain the variance and standard deviation with it?s significance. 5
6 (a) Describe the methods of evaluation of physical stability of emulsions. 5
(b) Describe the sterilization procedures for evaluation of parenterals. 5
(c) Describe the chi-square distribution. 5
7 (a) Write the methods for determination of the order of a reaction. 8
(b) Explain the photo degradation and it?s testing procedure. 7
8 (a) Discuss the methods for improvement of aques solubilty of drugs. 8
(b) Write Heckle equation and draw Heckle plots for porosity and explain them. 7
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