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Firstranker's choice Code No. 1159/PCI
FACULTY OF PHARMACY
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M. Pharmacy (Pharmacognosy) I-Semester (PCI) (Main) Examination, February 2018Subject: Phytochemistry
Time: 3 Hrs Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
- (a) Write the chemistry, biosynthesis, mechanism of action and chemical tests for Digitoxin.
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(b) Write the chemistry and analogs of artemesin. - Write about the chemistry of:
(i) Quinine
(ii) Withanolides
(iii) Sennosides - (a) Define and write the selection and optimization of lead compounds in Drug Discovery with suitable examples.
- Discuss spectral characters to elucidate the chemical structure of Menthol.
- Write the source, chemical structure and method of isolation of:
i) Quinine ii) Sennosides iii) Piperine. - Write a note on:
(i) Phases of clinical trials
(ii) Applications of HPTLC - Define and describe different types of extraction and extract techniques with advantages and disadvantages of each technique.
- Explain the principle, instrumentation, detectors and applications of HPTLC.
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