Download OU M.Pharma Pharmacology 1st Sem 2019 13156PCI Cellular And Molecular Pharmacology Question Paper

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FACULTY OF PHARMACY

M. Pharmacy (Pharmacology) I - Semester (PCI) (Main & Backlog) Examination, February 2019

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Subject: Cellular and Molecular Pharmacology

Time: 3 Hrs Max. Marks: 75

Note: Answer any five questions. All questions carry equal marks.

1. 1. Explain structure and function of cell organelles and genome organization. 8
   2. Explain how cell cycle will be regulated? 7

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2. 1. What do you understand about secondary messenger? 8
   2. Write descriptive notes on tyrosine kinase and nuclear receptors. 7

3. Explain in detail various types of intracellular signaling pathways (Cyclic AMP, MAOK, JAK and STAT). 15

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4. 1. Write a note on principle and application of genomic tools. 8
   2. What do you understand about DNA electrophoresis? 7
5. 1. Write a note on gene mapping and cloning of disease gene. 8

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   2. Write a note on metabolomics and proteomics. 7
6. 1. Explain in detail various types of gene transfer techniques. 8
   2. Write a descriptive note on gene sequencing and micro array technique. 7

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7. 1. Write a descriptive note on glucose uptake and calcium influx assay. 8
   2. Explain various types of cell culture techniques. 7
8. 1. Write a note on principle and application of various cell viability assays. 10
   2. Write a note on Biosimilars. 5

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