Download VNSGU MBBS 2010 2nd Year R 1569 Pharmacology Paper I Question Paper

Download VNSGU ((Veer Narmad South Gujarat University)) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2010 2nd Year R 1569 Pharmacology Paper I Previous Question Paper

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ect Code No.
:
Fillup strictly the details of 4, signs on your answer book.
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Name of the Examination :
S. Y. M. B. B. S.
Name of the Subject :
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I
Pharmacology - 1
5 6 9
Nil u
p-Section No. (1, 2, ) :
R-1569
Second Year M. B. B. S. Examination
February - 2010
Pharmacology : Paper - I
Time : Hours] [Total Marks : 40
Instructions :
(1)
Seat No. :
11111111111111
(2) Figures at right indicate marks.
(3)
Answers should be brief and to the point.
(4) Give suitable examples where needed.
(5)
Draw diagrams if necessary.
1 Answer the following : 9
(a) What is double blind study in a clinical trial?
(b) Name 2 (two) drugs that block the axonal uptake of
noradrenaline.
(c) What are prodrugs? Explain giving one example.
(d) Why is tropicamide preferred over atropine for
fundoscopy?
(e) Nasal decongestants should not be used for long
periods. Give reason.
(f) Enalapril may cause dry cough as an adverse reaction.
The same is not seen with Losartan. Why?
(g) Why is it preferable to use corticosteriods by inhalation
rather than oral route in chronic bronchial asthma?
(h) What is Monday Morning sickness?
(i) What is orphan drug? Give one example.
R-1569] 1 [Contd...
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LSubj
ect Code No.
:
Fillup strictly the details of 4, signs on your answer book.
w-
-
Name of the Examination :
S. Y. M. B. B. S.
Name of the Subject :
sai
4
q ?- Frial-actA [
43141 7-1
R`
1,41 41441
.
I
Pharmacology - 1
5 6 9
Nil u
p-Section No. (1, 2, ) :
R-1569
Second Year M. B. B. S. Examination
February - 2010
Pharmacology : Paper - I
Time : Hours] [Total Marks : 40
Instructions :
(1)
Seat No. :
11111111111111
(2) Figures at right indicate marks.
(3)
Answers should be brief and to the point.
(4) Give suitable examples where needed.
(5)
Draw diagrams if necessary.
1 Answer the following : 9
(a) What is double blind study in a clinical trial?
(b) Name 2 (two) drugs that block the axonal uptake of
noradrenaline.
(c) What are prodrugs? Explain giving one example.
(d) Why is tropicamide preferred over atropine for
fundoscopy?
(e) Nasal decongestants should not be used for long
periods. Give reason.
(f) Enalapril may cause dry cough as an adverse reaction.
The same is not seen with Losartan. Why?
(g) Why is it preferable to use corticosteriods by inhalation
rather than oral route in chronic bronchial asthma?
(h) What is Monday Morning sickness?
(i) What is orphan drug? Give one example.
R-1569] 1 [Contd...
2 Answer any three of the following : 9
(a) Explain with suitable examples how change in pH of
urine is helpful in therapeutics. Mention drugs used
to alkalinize urine.
Enumerate various antiplatelet drugs. Discuss
therapeutic uses of these agents in relation to
cardiovascular system with pharmacological basis.
What is paradoxical tachycardia produced by quinkline?
How can it be prevented? - Explain.
Compare and contrast properties of succinylcholine and
d-tubocuranine (d-tz).
Enumerate various indications of heparin. How will
you monitor the anticoagulant therapy?
3 Answer any three of the following : 12
(a) Enlist various ACE Inhibitors. Discuss the clinical uses
and adverse effects of ACE Inhibitors.
(b)
Discuss the role of cardiac glycosides in a patient with
congestive cardiac failure.
(c) Discuss Oral Rehydration Therapy in Management of
diarrhoea.
(d) What is DRC? Explain competitive and non competitive
antagonism with the help of DRC. Give two examples
each of competitive and non competitive antagonism.
(e) Explain giving three examples the importance of abrupt
drug withdrawal in therapeutics.
4 Answer any two of the following : 10
(a) Discuss Vd, clearance and half life of a drug. Giving
suitable examples explain their importance in clinical
practise.
(b)
Discuss various drug-drug interactions in therapeutics
giving suitable examples.
(c) Enumerate various 0 blockers. Discuss their uses
giving the pharmacological basis for each use you
mention.
R-1569] 2 [ 400 ]
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