Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination – May 2012
[Time: 3 Hours] [Max. Marks: 100]
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MEDICINAL CHEMISTRY - II (NATURAL PRODUCTS)
PAPER IV
(RS 2 & RS 3)
Q.P. CODE: 9234
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Discuss the chemical degradation, synthesis and spectral data of vincristine
- a) Write the chemistry of female sex hormones and their role
b) Write a note on third generation cephalosporins - a) Discuss in detail amido penicillins giving its clinical significances
b) Write a note on human insulin
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Write the mechanism of action of alkylating agents
- Explain monobactams and clavulanic acid analogues as antibiotics
- Explain the chemistry and SAR of insulin
- Explain Antiparasitic purines
- Explain chemical degradation of cardiac glycosides
- Discuss the chemistry of adrenal cortex hormones
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SHORT NOTES 2 X 5 = 10 Marks
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- Explain the active constituents and uses of Swertia chirata
- Write a note on Allopurinol
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