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Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - May 2012
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[Time: 3 Hours] [Max. Marks: 100]
ADVANCED PHARMACOLOGY AND TOXICOLOGY
PAPER II
(RS 2 & RS 3)
Q.P. CODE: 9242
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
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a) Define Epilepsy and Seizure; classify the epileptic seizures
b) Classify anti epileptic agents with examples, describe the mechanism of action, pharmacology and mention the adverse reactions and drug interactions of Phenytoin.
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a) Explain the pathophysiology of arrhythmia
b) Classify anti arrhythmics with examples and explain in detail the pharmacology of Quinidine and mention its drug interactions
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a) Explain in detail about immunomodulators and classify them
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b) Write notes on drugs used for Rheumatoid arthritis.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Catecholamines
- Mechanism of multi drug resistance (MDR)
- D-Tubocurarine
- Biotransformation and toxicokinetics
- Explain the mechanism of action and mention the adverse reactions of Oral antidiabetics.
- Anti Retro viral therapy for AIDS
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SHORT NOTES 2 X 5 = 10 Marks
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- Opioid receptors
- Furosemide
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