Rajiv Gandhi University of Health Sciences, Bangalore
First Year M.Pharm Degree Examination – May 2012
[Time: 3 Hours] [Max. Marks: 100]
ADVANCED PHARMACEUTICAL ANALYSIS
PAPER IV (RS 2 & RS 3)
Q.P. CODE: 9294
Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. Answer all questions
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LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Explain the principle and procedure for the evaluation of rabies antiserum and rabies vaccine
- Explain the assay of any two radiopharmaceuticals
- Explain the sterility testing of diclofenac sodium injection
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- What is pyrogen test? Explain
- Define refractive index and viscosity. Explain its importance in pharmaceutical analysis
- Write a note on the assay of Urokinase
- Explain the microbiological assay of vitamin with a suitable example
- Explain thermogravimetric curve for any one compound with required reactions
- What is the importance of effectiveness of antimicrobial preservative? How is it tested
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SHORT NOTES 2 X 5 = 10 Marks
- How is plague vaccine analyzed? Explain
- Explain ruggedness and robustness with reference to analytical method validation
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