Download RGUHS M.Pharmacy First Year May 2016 9348 Medicinal Chemistry Ii Natural Products Revised Scheme 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) May 2016 9348 Medicinal Chemistry Ii Natural Products Revised Scheme 4 Question Paper.

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - May 2016
[Time: 3 Hours] [Max. Marks: 100]
Medicinal Chemistry-II (Natural Products)
(Revised Scheme 4)
Q.P. CODE: 9348
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.

LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. Elucidate the structure of reserpine.
2. With suitable examples, describe the modifications carried out to obtain orally active penicillins
and cephalosporins.
3. Discuss the chemistry and biological importance of male and female sex hormones.

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. Give the structure and function of any two vinca alkaloids and elucidate the structure of any
one of them.
5. What are cardiac glycosides? Explain their chemistry and SAR.
6. Explain the chemical features and mechanism of purine and pyramidine antimetabolites as a
Anti-neoplastic agents.
7. Write the synthesis of an anti-fungal agent and an antipseudomonal penicillin.
8. Write a note on microbial conversions as tool in the preparation of drugs.
9. Write a note on chemistry of fat soluble vitamins.

SHORT NOTES 2 X 5 = 10 Marks
10. Write the synthesis of an antipseudomonal cephalosporin.
11. Write the structures of Nocardicins with their therapeutic uses.

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