Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) Nov 2011 9202 Advanced Organic Chemistry Rs 2 And Rs 3 Question Paper.
Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - Nov 2011
[Time: 3 Hours] [Max. Marks: 100]
ADVANCED ORGANIC CHEMISTRY
(RS 2 & RS 3)
Q.P. CODE: 9202
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. a) Discuss in detail the mechanism of nucleophilic substitution reaction taking suitable
examples. Critically discuss the factors that affect the rates of SN1 and SN2 reaction.
b) Comment on the kinetics of NSR
2. a) Discuss the chemistry of phenothiazine derivatives of pharmaceutical importance. Explain
the synthesis for a drug with phenothiazine nucleus
b) Add a note on pyrroles
3. a) Mention the importance of oxidation reaction in organic synthesis. Illustrate your answer
with oppeneauer oxidation
b) Microwave irradiation techniques
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. Discuss free radical addition reaction by initiation of peroxide. Write a note on free radical
polymerization of alkenes
5. Discuss the formation, structure, stability and reactions involving the carbocation
6. Explain the mechanism involved in E1 and E2 reactions with suitable examples
7. Describe the synthesis of any four drugs containing six membered heterocyclic ring
8. Give the methods of synthesis and applications of acetoacetic ester
9. Explain the mechanism of catalytic hydrogenation with suitable examples
SHORT NOTES 2 X 5 = 10 Marks
10. Write the mechanism involved in pericyclic reaction with example
11. Techniques used in stereomeric separation and their applications
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This post was last modified on 20 December 2019