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Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination – Nov 2011
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[Time: 3 Hours] [Max. Marks: 100]
PHARMACEUTICAL AND COSMETIC ANALYSIS
(RS 2 & RS 3)
Q.P. CODE: 9222
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- a) Explain Volhard's and modified Volhard's method for the estimation of Halide with suitable examples.
b) Explain the quality control of tablets. - a) Briefly discuss the determination of water by titration with Karl Fischer Reagent (KFR).
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b) What are PM indicators? Explain in detail the principles and applications of pM indicators in complexometric titrations - a) Discuss briefly various pharmaceutical applications of electro-analytical methods like potentiometry, polarography and amperometry.
b) Write in detail the various qualitative and in quantitative determination of emulsifiers and stabilizers in pharmaceutical formulations.
SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- State the pharmaceutical applications of redox titrations with suitable examples from official drugs in I.P. 1996.
- Write in detail the principles and procedures of titrations involving halogenated salt of bases.
- Briefly describe the theory and applications of acid base indicators.
- Discuss principles and applications of titration and the displacement of one complex by another.
- Write a note on safety for cosmetic products.
- Give a detail account of principles and applications of high frequency titration.
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SHORT NOTES 2 X 5 = 10 Marks
- Write a brief note on diazotization titration.
- Write a note on thermo-gravimetric analysis with examples.
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