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9234_2011_2_S202.doc
Rajiv Gandhi University of Health Sciences
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First Year M.Pharm Degree Examination – Nov 2011
[Time: 3 Hours] [Max. Marks: 100]
MEDICINAL CHEMISTRY - II (NATURAL PRODUCTS)
PAPER IV
(RS 2 & RS 3)
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Q.P. CODE: 9234
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- a) Elucidate the structure of papavarine.
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b) How will you identify morphine? - a) Classify oestrogenic hormones with suitable examples.
b) Write the chemistry and development of antifertility agents - a) Classify cardiac glycosides with suitable examples.
b) Discuss the SAR of cardiac glycosides.
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Give a brief chemistry of emetine.
- Classify antibiotics. What are the degradation products of penicillin.
- Explain the role of steroids in various diseases
- Give a brief chemistry of cephalosporin's
- Discuss the role of Swertia chirata.
- Briefly discuss vincristine in the cancer therapy.
- Carbapenams and Monobactams.
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SHORT NOTES 2 X 5 = 10 Marks
- Differences between cardinolides and bufadienolides.
- Trigonella foenum-graecum in diabetic therapy.
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