Rajiv Gandhi University of Health Sciences, Karnataka
First Year M. Pharm Degree Examination – Nov 2011
[Time: 3 Hours] [Max. Marks: 100]
MOLECULAR BIOLOGY
PAPER IV (RS 2 & RS 3)
Q.P. CODE: 9244
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Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Describe DNA sequencing, mapping and cloning of human genes
- Discuss the various steps involved in the production of a recombinant protein using recombinant technology with neat labeled diagrams
- Define cell culture. Discuss the various culture mediums, culture conditions to be followed to culture the mammalian cells with suitable examples
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Gene therapy for cancer
- Human genome project
- Various forces involved in the protein-protein interaction and protein-ligand binding
- Catalytic antibodies and its therapeutic application
- Structural features and functions of plasma membranes
- Apoptosis
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SHORT NOTES 2 X 5 = 10 Marks
- LCR
- Anti sense Technology
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