Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) Nov 2011 9312 Pharmaceutical Biotechnology I Rs 2 And Rs 3 Question Paper.
Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - Nov 2011
[Time: 3 Hours] [Max. Marks: 100]
PHARMACEUTICAL BIOTECHNOLOGY - I
(RS 2 & RS 3)
Q.P. CODE: 9312
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any FOUR) 4 X 25 = 100 Marks
1. a) Define taxonomy, species, strain and binomial system. Discuss numerical taxonomy
b) Differentiate anabolism from catabolism. Explain glycolysis, with respect to carbohydrate
metabolism
2. a) Enlist any four important characteristics of viruses and discuss the replication process of
animal viruses containing RNA
b) Describe the nutritional requirements of bacteria with specific examples and explain the
mechanisms of substrate entry into the cell
3. a) Define Mutation and enlist various mutagens with specific examples. Discuss various strain
improvement techniques
b) Differentiate primary screening from secondary screening. Discuss the detection methods
and briefly outline the assay methods of fermentation products
4. a) Discuss the production of citric acid by fermentation and mention its uses
b) Explain the salient features of mixed fermentation and discuss animal cell culture techniques
5. a) Discuss the production of penicillin by fermentation process
b) What are the advantages of microbial transformations over other methods? Discuss
microbial transformations of alkaloids and terpenes
6. Write short notes on:
a) Growth of microorganisms and general considerations
b) Aerobic respiration and anaerobic respiration
c) Ergot alkaloids
d) Role of plasmids in antibiotic resistance
e) Patents
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This post was last modified on 20 December 2019