Rajiv Gandhi University of Health Sciences
First Year M.Pharm Degree Examination - May 2011
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[Time: 3 Hours] [Max. Marks: 100]
PREFORMULATION AND PRODUCTION MANAGEMENT
(RS 2 & RS 3)
Q.P. CODE: 9282
Your answers should be specific to the questions asked.
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Draw neat labeled diagrams wherever necessary. Answer all questions
LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
- Explain the concepts of pre-formulation with special emphasis on study of stability, interactions with excipient and physico-chemical characteristics of drug molecules.
- Discuss about ISO 9000 series. Explain the documentation practices that are ideally implemented in a production unit.
- Write in detail pilot plant scale up concepts and techniques for parenterals
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SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
- Effluent treatment in pharmaceutical industries
- Personnel training.
- Formulation aspects of medicated lozenges
- Centralized purchasing
- Salient features of GMP
- Classical optimization
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SHORT NOTES 2 X 5 = 10 Marks
- GATT and trips
- Inventory models.
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