Download RGUHS M.Pharmacy First Year 2010 Oct Advanced Pharmacology And Toxicology Paper Ii Revised Scheme 2 Question Paper

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Rajiv Gandhi University of Health Sciences

First Year M.Pharm Degree Examination - October 2010

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[Time: 3 Hours]

ADVANCED PHARMACOLOGY AND TOXICOLOGY

PAPER II

(Revised Scheme 2)

Q.P. CODE : 9242

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Your answers should be specific to the questions asked.

[Max. Marks: 100]

Draw neat labeled diagrams wherever necessary. Answer all questions

LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks

1. a) Define a neurotransmitter
   

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   b) Write the pre-requirements to be a neurotransmitter
   c) Explain the types of receptors on which Neurotransmitters act
2. a) Classify antihypertensive drugs
   b) Discuss the mechanism of action, pharmacology, toxicology and uses of calcium channel blockers.
   c) Add a note on role of oral diuretics on hypertension

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3. a) Classify the antibiotics according to their mechanism
   b) Write down the mechanism of antibiotic resistance with the uses of ß – lactam antibiotics
   c) Discuss the spectrum of activity, adverse effects and uses of ß- lactam antibiotics

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks

1. HMG CoA reductase inhibitors

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2. Peripherally acting skeletal muscle relaxants
3. Ligand gated ion channels
4. Antiparkinsonism drugs
5. Role of prostaglandins
6. Antimetabolites in cancer chemotherapy

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SHORT NOTES 2 X 5 = 10 Marks

1. Insulin and its preparations
2. Specific COX II inhibitors

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