Download RGUHS M.Pharmacy First Year 2015 November 9351 Molecular Biology RS 4 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M Pharma (Master of Pharmacy) First Year (1st Year) 2015 November 9351 Molecular Biology RS 4 Question Paper.

Rajiv Gandhi University of Health Sciences
First Year M. Pharm Degree Examination - NOVEMBER 2015
[Time: 3 Hours] [Max. Marks: 100]
Molecular Biology
(Revised Scheme 4)
Q.P. CODE: 9351
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.

LONG ESSAY (Answer any TWO) 2 X 20 = 40 Marks
1. Explain various phases of cell cycle with a diagrammatic representation. Enumerate the various
checkpoints in cell cycles. Add a note on regulators and modifiers of cell cycle. (10+4+6)
2. What is gene expression? Explain the process of gene expression in eukaryotic cell. Enumerate
the genetic elements that control the gene expression. (2+12+6)
3. List various cell signaling and communication pathways between cells. What are biosensors?
Explain the construction and applications of biosensors. (4+2+8+6)

SHORT ESSAY (Answer any FIVE) 5 X 10 = 50 Marks
4. a) Explain the applications of rDNA technology.
b) Write a note on plasma membrane transport proteins and their inhibitors. (5+5)
5. Explain the events of apoptosis. Add a note on regulators of apoptosis. (6+4)
6. What is gene mapping? Name and explain various methods of gene mapping. (2+2+6)
7. Write the principles and applications of radio-ligand binding assay. (5+5)
8. With a neat-labeled diagram, explain the structure and functions of cell membrane and
mitochondria. (5+5)
9. a) Explain salient feature of various vectors used in gene therapy.
b) Explain the principle of antisense technology. (5+5)

SHORT NOTES 2 X 5 = 10 Marks
10. Write a note on pharmacological applications of animal tissue culture.
11. Explain in brief the concept of human genome project.

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