Download B.Pharm 2020 Feb 4th Sem Medicinal Chemistry II Question Papers

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(LQ 4271) FEBRUARY 2020 Sub. Code: 4271
B.PHARM. EXAMINATION
FOURTH YEAR
PAPER V ? MEDICINAL CHEMISTRY - II

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Q.P. Code : 564271
Time: Three hours Maximum: 100 Marks
I. Elaborate on: (2 x 20 = 40)

1. a) Define and classify anti-malarial drug and write SAR of anti-malarial drugs.

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b) Discuss chemistry a nd degradation of penicillin and write synsis of
Chloramphenicol.
2. a) Classify syntic an ti-bacterials and write the mechanism and SAR of
sulphonamides.
b) Write synsis of any two sulpha drugs.

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II. Write notes on: (8 x 5 = 40)

1. Write note on anticancer antibiotics and ir mechanism of action.
2. Write short note on Glucocorticoids.

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3. Write note on oral Hypoglycemic agents.
4. Write short notes on combinatorial chemistry.
5. Write note on Anlmintic drugs.
6. Classify antihypertensive drugs with example.
7. Classify local anti-infective agents. Write structur e and use of butoconazole

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and Griseofulvin.
8. Explain chemistry of Oestrogen.

III. Short answers on: (10 x 2 = 20)

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1. Structure and use of Phenformin.
2. Structure and use of minoxidil.
3. SAR of tetracyclines.
4. Mechanism of action of antihyperlipidemic drugs.
5. Write synsis of cisplatin and give its uses.

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6. Insulin preparations.
7. Antithyroid agents.
8. Classify antiarrhythmic agents.
9. Write struct ure of any two antimetabolites.
10. Define Cardiotonic and Vasodilators.

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