Download Hemwati Nandan Bahuguna Uttarakhand Medical Education University (HNBUMU) Medical Entrance Exam 2020 Jan Physiology Question Paper With Answer Previous Question Paper With Solution
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
10. Cell bodies of the neurons which carry taste sensation from the anterior 2/3
rd
of the
tongue are located in:
a. Trigeminal nerve ganglion
b. Geniculate ganglion
c. Otic ganglion
d. Superior cervical ganglion
11. Respiratory centre is situated in:
a. Medulla oblongata
b. Spinal cord
c. Midbrain
d. Hypothalamus
12. Sensations of pain from teeth and temperature are carried by
a. Corticospinal tract
b. Corticobulbar tract
c. Lateral spinothalamic tract
d. Ventral spinothalamic tract
13. Group B fibers are present in:
a. Intrafusal fibers of the muscle spindle
b. Golgi tendon apparatus
c. Autoonomic preganglionic fibers
d. Spinothalamic tracts
14. Lesions within the basal ganglia produce the following signs except:
a. Hypotonia
b. Tremor
c. Hemiballismus
d. Athetosis
15. In conn?s disease, there is an excess of:
a. Adrenaline
b. Aldosterone
c. Cortisol
d. Noradrenaline
16. Which of the following hormones is released from the posterior pituitary?
a. ACTH
b. Antidiuretic hormone
c. Growth hormone
d. Luetinizing hormone
17. Which of the following is associated with a low concentration of ionized calcium in
the serum?
a. Hypothyroidism
b. Osteogenesis imperfecta
c. Paget's disease of the bone
d. Tetany
18. Which hormone is released when serum calcium decreases
a. Parathormone
b. Calcitonin
c. Thyroxine
d. Adrenaline
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
10. Cell bodies of the neurons which carry taste sensation from the anterior 2/3
rd
of the
tongue are located in:
a. Trigeminal nerve ganglion
b. Geniculate ganglion
c. Otic ganglion
d. Superior cervical ganglion
11. Respiratory centre is situated in:
a. Medulla oblongata
b. Spinal cord
c. Midbrain
d. Hypothalamus
12. Sensations of pain from teeth and temperature are carried by
a. Corticospinal tract
b. Corticobulbar tract
c. Lateral spinothalamic tract
d. Ventral spinothalamic tract
13. Group B fibers are present in:
a. Intrafusal fibers of the muscle spindle
b. Golgi tendon apparatus
c. Autoonomic preganglionic fibers
d. Spinothalamic tracts
14. Lesions within the basal ganglia produce the following signs except:
a. Hypotonia
b. Tremor
c. Hemiballismus
d. Athetosis
15. In conn?s disease, there is an excess of:
a. Adrenaline
b. Aldosterone
c. Cortisol
d. Noradrenaline
16. Which of the following hormones is released from the posterior pituitary?
a. ACTH
b. Antidiuretic hormone
c. Growth hormone
d. Luetinizing hormone
17. Which of the following is associated with a low concentration of ionized calcium in
the serum?
a. Hypothyroidism
b. Osteogenesis imperfecta
c. Paget's disease of the bone
d. Tetany
18. Which hormone is released when serum calcium decreases
a. Parathormone
b. Calcitonin
c. Thyroxine
d. Adrenaline
19. Due fear which of the following hormones increases rapidly :
a. Growth hormones
b. Epinephrine
c. Corticosteroid
d. Thyroid hormone
20. A child with stunted growth with a stuffed ? belly, and short stature with mental
retardation is suffering from the deficiency of which of the following:
a. Thyroxine
b. Growth hormone
c. Rickets
d. Parathyroid
21. Trousseau?s sign and chovstek?s sings are positive in:
a. Hyperparathyroidism
b. Hypothyroidism
c. Hypoparathyroidism
d. Hyperthyroidism
22. In jaundice, there is an unconjugated hyperbilirubinemia which is most likely due to
a. Hepatitis
b. Cirrhosis
c. Obstruction of bile canaliculi
d. Increased break down of red cells
23. Histamine stiumlate the secretion of:
a. Gastrin by stomach
b. Pancreatic enzymes
c. HCL by stomach
d. Amylase by salivary gland
24. The most important function of hydrochloric acid in the stomach is:
a. Destruction of bacteria
b. Neutralization of chyme
c. Activation of pepsinogen
d. Stimulation of pancreatic secretion
25. Pancreas produce:
a. Pepsinogen
b. Chymotrypsinogen
c. Hydrochloric acid
d. All of the above
26. Intrinsic factor, which helps in absorption of Vit. B
12
is produced by :
a. Parietal cells of stomach
b. Chief cells of stomach
c. Beta cells of pancreas
d. Goblet cells
27. Maximum secretory glands in stomach are:
a. Fundic glands
b. Pyloric glands
c. Gastric glands
d. Brunner's glands
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
10. Cell bodies of the neurons which carry taste sensation from the anterior 2/3
rd
of the
tongue are located in:
a. Trigeminal nerve ganglion
b. Geniculate ganglion
c. Otic ganglion
d. Superior cervical ganglion
11. Respiratory centre is situated in:
a. Medulla oblongata
b. Spinal cord
c. Midbrain
d. Hypothalamus
12. Sensations of pain from teeth and temperature are carried by
a. Corticospinal tract
b. Corticobulbar tract
c. Lateral spinothalamic tract
d. Ventral spinothalamic tract
13. Group B fibers are present in:
a. Intrafusal fibers of the muscle spindle
b. Golgi tendon apparatus
c. Autoonomic preganglionic fibers
d. Spinothalamic tracts
14. Lesions within the basal ganglia produce the following signs except:
a. Hypotonia
b. Tremor
c. Hemiballismus
d. Athetosis
15. In conn?s disease, there is an excess of:
a. Adrenaline
b. Aldosterone
c. Cortisol
d. Noradrenaline
16. Which of the following hormones is released from the posterior pituitary?
a. ACTH
b. Antidiuretic hormone
c. Growth hormone
d. Luetinizing hormone
17. Which of the following is associated with a low concentration of ionized calcium in
the serum?
a. Hypothyroidism
b. Osteogenesis imperfecta
c. Paget's disease of the bone
d. Tetany
18. Which hormone is released when serum calcium decreases
a. Parathormone
b. Calcitonin
c. Thyroxine
d. Adrenaline
19. Due fear which of the following hormones increases rapidly :
a. Growth hormones
b. Epinephrine
c. Corticosteroid
d. Thyroid hormone
20. A child with stunted growth with a stuffed ? belly, and short stature with mental
retardation is suffering from the deficiency of which of the following:
a. Thyroxine
b. Growth hormone
c. Rickets
d. Parathyroid
21. Trousseau?s sign and chovstek?s sings are positive in:
a. Hyperparathyroidism
b. Hypothyroidism
c. Hypoparathyroidism
d. Hyperthyroidism
22. In jaundice, there is an unconjugated hyperbilirubinemia which is most likely due to
a. Hepatitis
b. Cirrhosis
c. Obstruction of bile canaliculi
d. Increased break down of red cells
23. Histamine stiumlate the secretion of:
a. Gastrin by stomach
b. Pancreatic enzymes
c. HCL by stomach
d. Amylase by salivary gland
24. The most important function of hydrochloric acid in the stomach is:
a. Destruction of bacteria
b. Neutralization of chyme
c. Activation of pepsinogen
d. Stimulation of pancreatic secretion
25. Pancreas produce:
a. Pepsinogen
b. Chymotrypsinogen
c. Hydrochloric acid
d. All of the above
26. Intrinsic factor, which helps in absorption of Vit. B
12
is produced by :
a. Parietal cells of stomach
b. Chief cells of stomach
c. Beta cells of pancreas
d. Goblet cells
27. Maximum secretory glands in stomach are:
a. Fundic glands
b. Pyloric glands
c. Gastric glands
d. Brunner's glands
28. Which of the following coagulation factors is deficient in classical hemophilia?
a. VIII
b. IX
c. X
d. XII
29. Which of the following is one for a patient on coumarin ( warfarin) therapy:
a. Partial thromboplastin time ( PTT)
b. Prothrombin time (PT)
c. Bleeding time (BT)
d. Capiallary fragility test (CFT)
30. The anticoagulant of choice used in the blood bank is:
a. Calcium oxalate
b. Heparin solution
c. Acid citrate dextrose solution
d. Sodium fluoride
31. To preserve blood for transfusion later:
a. Dilute with equal volume of 0.9% saline
b. Add solution of sodium citrate
c. Add solution of calcium chloride
d. Add fibrinogen
32. T- lymphocytes function to :
a. Antibody production
b. Complement activation
c. Lymphokine production and delayed hypersensitivity
d. Immediate hypersensitivity
33. Haemoglobin is the major buffer in blood, bicarbonate ions diffuses out of
erythrocyte into plasma in exchange of:
a. Potassium
b. Phosphate
c. Carbonic acid
d. Chloride ion
34. The eosinophil count in the peripheral blood smear is increased in:
a. Allergic conditions
b. Anaemia
c. Polycythemia
d. Typhoid fever
35. During exercise:
a. Cerebral blood flow increases if there is increase in systolic blood pressure
b. Body temperature increases
c. Blood flow to muscle increases after 1? minute
d. Lymphatic flow from muscle decrease
36. The percentage of body water is greater in
a. Male than in females
b. Children than in adult
c. Obese than in lean individuals
d. old than in young objects
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
10. Cell bodies of the neurons which carry taste sensation from the anterior 2/3
rd
of the
tongue are located in:
a. Trigeminal nerve ganglion
b. Geniculate ganglion
c. Otic ganglion
d. Superior cervical ganglion
11. Respiratory centre is situated in:
a. Medulla oblongata
b. Spinal cord
c. Midbrain
d. Hypothalamus
12. Sensations of pain from teeth and temperature are carried by
a. Corticospinal tract
b. Corticobulbar tract
c. Lateral spinothalamic tract
d. Ventral spinothalamic tract
13. Group B fibers are present in:
a. Intrafusal fibers of the muscle spindle
b. Golgi tendon apparatus
c. Autoonomic preganglionic fibers
d. Spinothalamic tracts
14. Lesions within the basal ganglia produce the following signs except:
a. Hypotonia
b. Tremor
c. Hemiballismus
d. Athetosis
15. In conn?s disease, there is an excess of:
a. Adrenaline
b. Aldosterone
c. Cortisol
d. Noradrenaline
16. Which of the following hormones is released from the posterior pituitary?
a. ACTH
b. Antidiuretic hormone
c. Growth hormone
d. Luetinizing hormone
17. Which of the following is associated with a low concentration of ionized calcium in
the serum?
a. Hypothyroidism
b. Osteogenesis imperfecta
c. Paget's disease of the bone
d. Tetany
18. Which hormone is released when serum calcium decreases
a. Parathormone
b. Calcitonin
c. Thyroxine
d. Adrenaline
19. Due fear which of the following hormones increases rapidly :
a. Growth hormones
b. Epinephrine
c. Corticosteroid
d. Thyroid hormone
20. A child with stunted growth with a stuffed ? belly, and short stature with mental
retardation is suffering from the deficiency of which of the following:
a. Thyroxine
b. Growth hormone
c. Rickets
d. Parathyroid
21. Trousseau?s sign and chovstek?s sings are positive in:
a. Hyperparathyroidism
b. Hypothyroidism
c. Hypoparathyroidism
d. Hyperthyroidism
22. In jaundice, there is an unconjugated hyperbilirubinemia which is most likely due to
a. Hepatitis
b. Cirrhosis
c. Obstruction of bile canaliculi
d. Increased break down of red cells
23. Histamine stiumlate the secretion of:
a. Gastrin by stomach
b. Pancreatic enzymes
c. HCL by stomach
d. Amylase by salivary gland
24. The most important function of hydrochloric acid in the stomach is:
a. Destruction of bacteria
b. Neutralization of chyme
c. Activation of pepsinogen
d. Stimulation of pancreatic secretion
25. Pancreas produce:
a. Pepsinogen
b. Chymotrypsinogen
c. Hydrochloric acid
d. All of the above
26. Intrinsic factor, which helps in absorption of Vit. B
12
is produced by :
a. Parietal cells of stomach
b. Chief cells of stomach
c. Beta cells of pancreas
d. Goblet cells
27. Maximum secretory glands in stomach are:
a. Fundic glands
b. Pyloric glands
c. Gastric glands
d. Brunner's glands
28. Which of the following coagulation factors is deficient in classical hemophilia?
a. VIII
b. IX
c. X
d. XII
29. Which of the following is one for a patient on coumarin ( warfarin) therapy:
a. Partial thromboplastin time ( PTT)
b. Prothrombin time (PT)
c. Bleeding time (BT)
d. Capiallary fragility test (CFT)
30. The anticoagulant of choice used in the blood bank is:
a. Calcium oxalate
b. Heparin solution
c. Acid citrate dextrose solution
d. Sodium fluoride
31. To preserve blood for transfusion later:
a. Dilute with equal volume of 0.9% saline
b. Add solution of sodium citrate
c. Add solution of calcium chloride
d. Add fibrinogen
32. T- lymphocytes function to :
a. Antibody production
b. Complement activation
c. Lymphokine production and delayed hypersensitivity
d. Immediate hypersensitivity
33. Haemoglobin is the major buffer in blood, bicarbonate ions diffuses out of
erythrocyte into plasma in exchange of:
a. Potassium
b. Phosphate
c. Carbonic acid
d. Chloride ion
34. The eosinophil count in the peripheral blood smear is increased in:
a. Allergic conditions
b. Anaemia
c. Polycythemia
d. Typhoid fever
35. During exercise:
a. Cerebral blood flow increases if there is increase in systolic blood pressure
b. Body temperature increases
c. Blood flow to muscle increases after 1? minute
d. Lymphatic flow from muscle decrease
36. The percentage of body water is greater in
a. Male than in females
b. Children than in adult
c. Obese than in lean individuals
d. old than in young objects
37. Meiotic division of male germ cells commence
a. During intra - uterine life
b. just before birth
c. by around 6 years after birth
d. by around 16 years
38. Primary cause of bleeding disorder in liver damage is due to
a. Decreased level of prothrombin
b. Lack of vitamin K
c. Platelet deficiency
d. Lack of vitamin B
39. T- lymphocytes play a primary role in
a. Production of Antibodies
b. production of lymphokines and delayed hypersensitivity
c. Activation of complement system
d. Immediate Hypersensitivity
40. Gut associated lymphoid tissue ( GALT) is primarily located in-
a. Lamina propria
b. Submucosa
c. Muscularis
d. Serosa
41. Which of the following events DO NOT occur in rods in response to light-
a. Structural changes in rhodopsin
b. Activation of transducin
c. Decreased intracellular cGMP
d. Opening of Na+ channels
42. Calcium ions triggers muscle contraction by binding to :
a. Actin
b. Myosin
c. Troponin
d. Tropomyosin
43. The contractile element in a skeletal muscle is present in:
a. Sarcolemma
b. Sarcoplasm
c. Myofibril
d. Endomysium
44. Contractile element in myofibril is:
a. H band
b. Sarcoplasm
c. Sarcomere
d. A line
45. Skeletal muscles:
a. Contracts when calcium is taken up by sacroplasmic reticulum
b. Contracts when actin and myosin filaments shorten
c. Contraction is initiated by calcium binding to troponin
d. Contraction is initiated by calcium binding to tropomyosin
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Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
10. Cell bodies of the neurons which carry taste sensation from the anterior 2/3
rd
of the
tongue are located in:
a. Trigeminal nerve ganglion
b. Geniculate ganglion
c. Otic ganglion
d. Superior cervical ganglion
11. Respiratory centre is situated in:
a. Medulla oblongata
b. Spinal cord
c. Midbrain
d. Hypothalamus
12. Sensations of pain from teeth and temperature are carried by
a. Corticospinal tract
b. Corticobulbar tract
c. Lateral spinothalamic tract
d. Ventral spinothalamic tract
13. Group B fibers are present in:
a. Intrafusal fibers of the muscle spindle
b. Golgi tendon apparatus
c. Autoonomic preganglionic fibers
d. Spinothalamic tracts
14. Lesions within the basal ganglia produce the following signs except:
a. Hypotonia
b. Tremor
c. Hemiballismus
d. Athetosis
15. In conn?s disease, there is an excess of:
a. Adrenaline
b. Aldosterone
c. Cortisol
d. Noradrenaline
16. Which of the following hormones is released from the posterior pituitary?
a. ACTH
b. Antidiuretic hormone
c. Growth hormone
d. Luetinizing hormone
17. Which of the following is associated with a low concentration of ionized calcium in
the serum?
a. Hypothyroidism
b. Osteogenesis imperfecta
c. Paget's disease of the bone
d. Tetany
18. Which hormone is released when serum calcium decreases
a. Parathormone
b. Calcitonin
c. Thyroxine
d. Adrenaline
19. Due fear which of the following hormones increases rapidly :
a. Growth hormones
b. Epinephrine
c. Corticosteroid
d. Thyroid hormone
20. A child with stunted growth with a stuffed ? belly, and short stature with mental
retardation is suffering from the deficiency of which of the following:
a. Thyroxine
b. Growth hormone
c. Rickets
d. Parathyroid
21. Trousseau?s sign and chovstek?s sings are positive in:
a. Hyperparathyroidism
b. Hypothyroidism
c. Hypoparathyroidism
d. Hyperthyroidism
22. In jaundice, there is an unconjugated hyperbilirubinemia which is most likely due to
a. Hepatitis
b. Cirrhosis
c. Obstruction of bile canaliculi
d. Increased break down of red cells
23. Histamine stiumlate the secretion of:
a. Gastrin by stomach
b. Pancreatic enzymes
c. HCL by stomach
d. Amylase by salivary gland
24. The most important function of hydrochloric acid in the stomach is:
a. Destruction of bacteria
b. Neutralization of chyme
c. Activation of pepsinogen
d. Stimulation of pancreatic secretion
25. Pancreas produce:
a. Pepsinogen
b. Chymotrypsinogen
c. Hydrochloric acid
d. All of the above
26. Intrinsic factor, which helps in absorption of Vit. B
12
is produced by :
a. Parietal cells of stomach
b. Chief cells of stomach
c. Beta cells of pancreas
d. Goblet cells
27. Maximum secretory glands in stomach are:
a. Fundic glands
b. Pyloric glands
c. Gastric glands
d. Brunner's glands
28. Which of the following coagulation factors is deficient in classical hemophilia?
a. VIII
b. IX
c. X
d. XII
29. Which of the following is one for a patient on coumarin ( warfarin) therapy:
a. Partial thromboplastin time ( PTT)
b. Prothrombin time (PT)
c. Bleeding time (BT)
d. Capiallary fragility test (CFT)
30. The anticoagulant of choice used in the blood bank is:
a. Calcium oxalate
b. Heparin solution
c. Acid citrate dextrose solution
d. Sodium fluoride
31. To preserve blood for transfusion later:
a. Dilute with equal volume of 0.9% saline
b. Add solution of sodium citrate
c. Add solution of calcium chloride
d. Add fibrinogen
32. T- lymphocytes function to :
a. Antibody production
b. Complement activation
c. Lymphokine production and delayed hypersensitivity
d. Immediate hypersensitivity
33. Haemoglobin is the major buffer in blood, bicarbonate ions diffuses out of
erythrocyte into plasma in exchange of:
a. Potassium
b. Phosphate
c. Carbonic acid
d. Chloride ion
34. The eosinophil count in the peripheral blood smear is increased in:
a. Allergic conditions
b. Anaemia
c. Polycythemia
d. Typhoid fever
35. During exercise:
a. Cerebral blood flow increases if there is increase in systolic blood pressure
b. Body temperature increases
c. Blood flow to muscle increases after 1? minute
d. Lymphatic flow from muscle decrease
36. The percentage of body water is greater in
a. Male than in females
b. Children than in adult
c. Obese than in lean individuals
d. old than in young objects
37. Meiotic division of male germ cells commence
a. During intra - uterine life
b. just before birth
c. by around 6 years after birth
d. by around 16 years
38. Primary cause of bleeding disorder in liver damage is due to
a. Decreased level of prothrombin
b. Lack of vitamin K
c. Platelet deficiency
d. Lack of vitamin B
39. T- lymphocytes play a primary role in
a. Production of Antibodies
b. production of lymphokines and delayed hypersensitivity
c. Activation of complement system
d. Immediate Hypersensitivity
40. Gut associated lymphoid tissue ( GALT) is primarily located in-
a. Lamina propria
b. Submucosa
c. Muscularis
d. Serosa
41. Which of the following events DO NOT occur in rods in response to light-
a. Structural changes in rhodopsin
b. Activation of transducin
c. Decreased intracellular cGMP
d. Opening of Na+ channels
42. Calcium ions triggers muscle contraction by binding to :
a. Actin
b. Myosin
c. Troponin
d. Tropomyosin
43. The contractile element in a skeletal muscle is present in:
a. Sarcolemma
b. Sarcoplasm
c. Myofibril
d. Endomysium
44. Contractile element in myofibril is:
a. H band
b. Sarcoplasm
c. Sarcomere
d. A line
45. Skeletal muscles:
a. Contracts when calcium is taken up by sacroplasmic reticulum
b. Contracts when actin and myosin filaments shorten
c. Contraction is initiated by calcium binding to troponin
d. Contraction is initiated by calcium binding to tropomyosin
46. The following electrodes are used to detect the muscle activity without pain:
a. Surface electrode
b. Round electrode
c. Hook electrode
d. Needle electrode
47. Rigor mortis results after death is due to
a. Failure of acetylcholine to diffuse
b. Failure of ATP supply
c. Failure of break down of calcium bridges
d. None of the above
48. A decrease in the urine output is called :
a. Dysuria
b. Nocturia
c. Oliguria
d. Plyuria
49. In osmotic diurestis there is:
a. Increase in renal blood flow
b. Increase in glomerular filtration rate
c. Increase in NaCl concentration in urine
d. Decrease in reabsorption of Na Cl
50. Test for estimating kidney function is:
a. Serum creatinine
b. Serum phosphatase
c. Inulin test
d. Insulin test
51. Carbonic anhydrase in the kidney tubular cells is known to be associated with:
a. Urea
b. Chloride
c. Bicarbonate ion
d. Carbohydrate
52. Renin is released from the kidney in all except:
a. Sympathetic stimulation
b. Decrease in the concentration of sodium ions in the proximal tubules
c. Decrease in the concentration of sodium ions in the distal tubules
d. Fall in the BP
53. The kidney secrete all of the following hormones except:
a. Renin
b. Erythropoietin
c. Vasopressin
d. 1,2,5 Dihydroxy cholecalciferol
54. The glomerular filtration rate of the human kidney may be determined by
measuring the plasma clearance of:
a. PAH
b. Urea
c. Inulin
d. Glucose
FirstRanker.com - FirstRanker's Choice
Hemwati Nandan Bahuguna Uttarakhand Medical
Education University
Administrative?Block,?Govt.?Doon?Medical?College?Campus,?Dehrakhas,??
Patel?Nagar,?Dehradun???248001?
Phone:?0135???2723323?Fax:? 0135???2723323?
Website: www.hnbumu.ac.in? E?mail:?info.hnbumu@gmail.com
Ph.D. ENTRANCE EXAMINATION - 2020
Subject? :??Physiology? ? ? ??????????? Duration:?01:30?Hrs.?
Date?? :??06.01.2020? ? ??????????? Place:?Dehradun?
Max?Marks:?60?? ?
?
Student?Name:??????Invigilator?Name:??
?
Signature:???????Signature:?
?
?
1. The first heart sound is produced by the:
a. Closure of the aortic and pulmonary valves
b. Opening of the aortic and pulmonary valves
c. Closure of the mitral and tricuspid valves
d. Opening of the mitral and tricuspid valves
2. Parasympathetic stimulation of heart causes:
a. SA node decreases firing
b. Increased AV node excitability
c. Decreased ventricular contraction
d. Tachycardia
3. Normally, the rate of the heart beat in a human is determined by :
a. The bundle of His
b. All cardiac muscle
c. The sinoatrial node
d. The cervical ganglion
4. The ventricular repolarization in ECG is best seen in:
a. "P" wave
b. "Q" wave
c. "R" wave
d. "T" wave
5. Cardiac output is not affected by :
a. Heart rate
b. Peripheral resistance
c. Systolic blood pressure
d. Venous return
6. All the heart valves are open during which stage of cardiac cycle :
a. Systolic ejection
b. Isovolumetric relaxation
c. Isovolumetric contraction
d. None of the above
7. Increased functional demand on the heart produces increased size of the
myocardium by :
a. Hyperplasia
b. Hypertrophy
c. Fatty infiltration
d. Increased amounts of fibrous connective tissue
8. Hunger centre of brain is:
a. Hypothalamus
b. Stria nigra
c. Frontal lobe
d. Temporal lobe
9. Pain sensation from the lateral extremities is transmitted by :
a. Spino thalmamic tract
b. Dorsal column
c. Corticospinal tract
d. Spinocerebellar tract
10. Cell bodies of the neurons which carry taste sensation from the anterior 2/3
rd
of the
tongue are located in:
a. Trigeminal nerve ganglion
b. Geniculate ganglion
c. Otic ganglion
d. Superior cervical ganglion
11. Respiratory centre is situated in:
a. Medulla oblongata
b. Spinal cord
c. Midbrain
d. Hypothalamus
12. Sensations of pain from teeth and temperature are carried by
a. Corticospinal tract
b. Corticobulbar tract
c. Lateral spinothalamic tract
d. Ventral spinothalamic tract
13. Group B fibers are present in:
a. Intrafusal fibers of the muscle spindle
b. Golgi tendon apparatus
c. Autoonomic preganglionic fibers
d. Spinothalamic tracts
14. Lesions within the basal ganglia produce the following signs except:
a. Hypotonia
b. Tremor
c. Hemiballismus
d. Athetosis
15. In conn?s disease, there is an excess of:
a. Adrenaline
b. Aldosterone
c. Cortisol
d. Noradrenaline
16. Which of the following hormones is released from the posterior pituitary?
a. ACTH
b. Antidiuretic hormone
c. Growth hormone
d. Luetinizing hormone
17. Which of the following is associated with a low concentration of ionized calcium in
the serum?
a. Hypothyroidism
b. Osteogenesis imperfecta
c. Paget's disease of the bone
d. Tetany
18. Which hormone is released when serum calcium decreases
a. Parathormone
b. Calcitonin
c. Thyroxine
d. Adrenaline
19. Due fear which of the following hormones increases rapidly :
a. Growth hormones
b. Epinephrine
c. Corticosteroid
d. Thyroid hormone
20. A child with stunted growth with a stuffed ? belly, and short stature with mental
retardation is suffering from the deficiency of which of the following:
a. Thyroxine
b. Growth hormone
c. Rickets
d. Parathyroid
21. Trousseau?s sign and chovstek?s sings are positive in:
a. Hyperparathyroidism
b. Hypothyroidism
c. Hypoparathyroidism
d. Hyperthyroidism
22. In jaundice, there is an unconjugated hyperbilirubinemia which is most likely due to
a. Hepatitis
b. Cirrhosis
c. Obstruction of bile canaliculi
d. Increased break down of red cells
23. Histamine stiumlate the secretion of:
a. Gastrin by stomach
b. Pancreatic enzymes
c. HCL by stomach
d. Amylase by salivary gland
24. The most important function of hydrochloric acid in the stomach is:
a. Destruction of bacteria
b. Neutralization of chyme
c. Activation of pepsinogen
d. Stimulation of pancreatic secretion
25. Pancreas produce:
a. Pepsinogen
b. Chymotrypsinogen
c. Hydrochloric acid
d. All of the above
26. Intrinsic factor, which helps in absorption of Vit. B
12
is produced by :
a. Parietal cells of stomach
b. Chief cells of stomach
c. Beta cells of pancreas
d. Goblet cells
27. Maximum secretory glands in stomach are:
a. Fundic glands
b. Pyloric glands
c. Gastric glands
d. Brunner's glands
28. Which of the following coagulation factors is deficient in classical hemophilia?
a. VIII
b. IX
c. X
d. XII
29. Which of the following is one for a patient on coumarin ( warfarin) therapy:
a. Partial thromboplastin time ( PTT)
b. Prothrombin time (PT)
c. Bleeding time (BT)
d. Capiallary fragility test (CFT)
30. The anticoagulant of choice used in the blood bank is:
a. Calcium oxalate
b. Heparin solution
c. Acid citrate dextrose solution
d. Sodium fluoride
31. To preserve blood for transfusion later:
a. Dilute with equal volume of 0.9% saline
b. Add solution of sodium citrate
c. Add solution of calcium chloride
d. Add fibrinogen
32. T- lymphocytes function to :
a. Antibody production
b. Complement activation
c. Lymphokine production and delayed hypersensitivity
d. Immediate hypersensitivity
33. Haemoglobin is the major buffer in blood, bicarbonate ions diffuses out of
erythrocyte into plasma in exchange of:
a. Potassium
b. Phosphate
c. Carbonic acid
d. Chloride ion
34. The eosinophil count in the peripheral blood smear is increased in:
a. Allergic conditions
b. Anaemia
c. Polycythemia
d. Typhoid fever
35. During exercise:
a. Cerebral blood flow increases if there is increase in systolic blood pressure
b. Body temperature increases
c. Blood flow to muscle increases after 1? minute
d. Lymphatic flow from muscle decrease
36. The percentage of body water is greater in
a. Male than in females
b. Children than in adult
c. Obese than in lean individuals
d. old than in young objects
37. Meiotic division of male germ cells commence
a. During intra - uterine life
b. just before birth
c. by around 6 years after birth
d. by around 16 years
38. Primary cause of bleeding disorder in liver damage is due to
a. Decreased level of prothrombin
b. Lack of vitamin K
c. Platelet deficiency
d. Lack of vitamin B
39. T- lymphocytes play a primary role in
a. Production of Antibodies
b. production of lymphokines and delayed hypersensitivity
c. Activation of complement system
d. Immediate Hypersensitivity
40. Gut associated lymphoid tissue ( GALT) is primarily located in-
a. Lamina propria
b. Submucosa
c. Muscularis
d. Serosa
41. Which of the following events DO NOT occur in rods in response to light-
a. Structural changes in rhodopsin
b. Activation of transducin
c. Decreased intracellular cGMP
d. Opening of Na+ channels
42. Calcium ions triggers muscle contraction by binding to :
a. Actin
b. Myosin
c. Troponin
d. Tropomyosin
43. The contractile element in a skeletal muscle is present in:
a. Sarcolemma
b. Sarcoplasm
c. Myofibril
d. Endomysium
44. Contractile element in myofibril is:
a. H band
b. Sarcoplasm
c. Sarcomere
d. A line
45. Skeletal muscles:
a. Contracts when calcium is taken up by sacroplasmic reticulum
b. Contracts when actin and myosin filaments shorten
c. Contraction is initiated by calcium binding to troponin
d. Contraction is initiated by calcium binding to tropomyosin
46. The following electrodes are used to detect the muscle activity without pain:
a. Surface electrode
b. Round electrode
c. Hook electrode
d. Needle electrode
47. Rigor mortis results after death is due to
a. Failure of acetylcholine to diffuse
b. Failure of ATP supply
c. Failure of break down of calcium bridges
d. None of the above
48. A decrease in the urine output is called :
a. Dysuria
b. Nocturia
c. Oliguria
d. Plyuria
49. In osmotic diurestis there is:
a. Increase in renal blood flow
b. Increase in glomerular filtration rate
c. Increase in NaCl concentration in urine
d. Decrease in reabsorption of Na Cl
50. Test for estimating kidney function is:
a. Serum creatinine
b. Serum phosphatase
c. Inulin test
d. Insulin test
51. Carbonic anhydrase in the kidney tubular cells is known to be associated with:
a. Urea
b. Chloride
c. Bicarbonate ion
d. Carbohydrate
52. Renin is released from the kidney in all except:
a. Sympathetic stimulation
b. Decrease in the concentration of sodium ions in the proximal tubules
c. Decrease in the concentration of sodium ions in the distal tubules
d. Fall in the BP
53. The kidney secrete all of the following hormones except:
a. Renin
b. Erythropoietin
c. Vasopressin
d. 1,2,5 Dihydroxy cholecalciferol
54. The glomerular filtration rate of the human kidney may be determined by
measuring the plasma clearance of:
a. PAH
b. Urea
c. Inulin
d. Glucose
55. Brush border is seen in:
a. Bowman's capsule
b. Proximal convoluted tubule
c. Distal convoluted tubule
d. Loop of Henle
56. During inspiration when the diaphragm contracts, the intrapleural pressure
becomes:
a. More negative
b. Less negative
c. Positive
d. Equal to the intra alveolar pressure
57. A decrease in the arterial PO
2
is seen in:
a. Decrease in hemoglobin concentration of arterial blood
b. Paralysis of inspiratory muscles
c. Sluggish blood flow
d. High altitudes
58.The major sign of hypoventilationis:
a. Cyanosis
b. Dysponoea
c. Hypercapnia
d. Hypoxia
59. Most effective method of assessing breathing is by measuring:
a. Tidal volume
b. Respiratory rate
c. Alveolar ventilation
d. FEV 1
60. The volume of gas in the lungs at the end of normal expiration is
a. Expirratory reserve volume
b. Functional residual capacity
c. Residual volume
d. Inspiratory reserve volume
?
*********************************?
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This post was last modified on 21 September 2020