Download KUHS (Kerala University of Health Sciences) MBBS (Bachelor of Medicine and Bachelor of Surgery) 2019 August 2nd Year 201001 Pharmacology Paper I Previous Question Paper
Second Professional MBBS Degree Supplementary Examinations
July 2019
Pharmacology - Paper I
Time: 2 Hours Max Marks: 40
? Answer all questions
? Draw diagrams wherever necessary
Essays: (2x6=12)
1. Classify antiepileptic drugs. Describe the mechanism of action and adverse effects of
phenytoin (2+2+2)
2. Read the clinical problem and answer the following question:
An elderly male aged 70 years was brought to the outpatient department with
complaints of difficulty in passing urine, poor stream & post void dribbling. Examination
revealed that he had benign prostatic hypertrophy (BPH) and his BP was 160/ 100 mm
of Hg. (2+2+2).
? What drug will you prescribe to take care of both BPH & hypertension
? Explain the mechanism of action of the drug in this patient
? What do you understand by ?first dose effect? of Prazosin
Short Notes: (5x3=15)
3. First pass metabolism
4. Furosemide
5. Fibrinolytic drugs
6. Calcium channel blockers
7. Atypical antipsychotic agents
Write the Pharmacological basis for the use of: (3x1=3)
8. Levodopa and carbidopa combination in Parkinson?s disease
9. Fomepizole in methanol poisoning
10. Combination of adrenaline with lignocaine in infiltration local anesthesia
Write two uses and two adverse effects of the following drugs: (3x1=3)
11. Clonidine
12. Allopurinol
13. Diazepam
Choose the appropriate drug and Justify: (2x1=2)
14. Montelukast / Salbutamol in acute bronchial asthma
15. Thiazides / Spironolactone in patients using Lisinopril
Name the following (Two examples for each): (5x1=5)
16. Transdermal patch
17. Microsomal enzyme inducers
18. Drugs for open angle glaucoma
19. Cardio selective beta blocker
20. Plasma expanders
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This post was last modified on 26 March 2020