Download RGUHS B.Pharm 2020 4th Year-Final Year 2617 Instrumental And Bio Medical Analysis Revised Scheme 3 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) Bachelor of Pharmacy (B.Pharm) 2020 4th Year-Final Year 2617 Instrumental And Bio Medical Analysis Revised Scheme 3 Previous Question Paper

Rajiv Gandhi University of Health Sciences, Karnataka
IV Year B.Pharm Degree Examination ? 07-Jan-2020
Time: Three Hours





Max. Marks: 70 Marks
INSTRUMENTAL & BIO-MEDICAL ANALYSIS
(Revised Scheme ? 3)
Q.P. CODE: 2617
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
1.
What are bonded phase supports? Describe its importance in HPLC. Add a note on different
types of pumps and sample injection systems used in HPLC.
2.
What are the requirements of a potentiometric titration? Explain any one classical
potentiometric titration emphasizing on the electrodes used and methods commonly followed
for determination of titration end - point.
3.
Explain different development and detection techniques used in paper chromatography.
SHORT ESSAYS (Answer any Six)
6 x 5 = 30 Marks
4.
Outline differences between flame emission and atomic absorption spectrometric methods.
Write any two important applications for each of these techniques.
5.
Write the effect of polar and non-polar solvents on absorption spectra of molecules.
6.
Describe the principle of obtaining monochromatic radiations using Gratings with a neat
diagram.
7.
What is process validation? Explain its types.
8.
Justify the statement ? "Fluorimetric methods are said to be sensitive and selective".
9.
What are bulk property HPLC detectors? Explain the construction and working of any one of
them.
10. What is column chromatography? Explain the methodology and the principle involved in column
chromatographic technique.
11. Explain with suitable titration curves, the method to determine end-points in displacement type
of conductometric titrations.
SHORT ANSWERS
10 x 2 = 20 Marks
12. What is E-band? Give an example.
13. What is the scope of derivatization in gas chromatography? Give an example.
14. Write the electrode equation for a potentiometric electrode system comprising of Calomel
electrode and glass electrode in determination of hydrogen ion concentration of the solution.
15. Write any two applications of Nephelo-turbidimetric analysis.
16. What is the HRf? How and for what, compounds HRf is calculated.
17. Write the applications of ion-exchange chromatography.
18. What are dynodes in PMT? How is it different from the cathode present in such detectors?
19. What is the difference between frontal analysis and elution analysis?
20. What is concentration quenching and static quenching?
21. Write the composition and types of paper commonly used in paper chromatographic technique.
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