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Rajiv Gandhi University of Health Sciences, Karnataka
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III Year Pharm-D Degree Examination – 02-Jan-2020
Time: Three Hours
PHARMACOLOGY –II (RS & RS2)
Q.P. CODE: 2861
Your answers should be specific to the questions asked
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Draw neat, labeled diagrams wherever necessary
Max. Marks: 70 Marks
LONG ESSAYS (answer any two) 2 x 10 = 20 Marks
- What are aminoglycoside antibiotics? Write the mechanism of action, adverse reactions and therapeutic uses of streptomycin. (2+3+3+2)
- Describe the steps involved in recombinant DNA technology. Add a note on their pharmaceutical applications. (7+3)
- Classify anti-leprotic drugs with examples. Write the mechanism of action, adverse effects and therapeutic uses of dapsone. Add note on different forms of leprosy. (3+4+3)
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SHORT ESSAYS (answer any six) 6 x 5 = 30 Marks
- Write mechanism of action, adverse effects and therapeutic uses of warfarin.
- Enlist diuretics acting on ascending and descending loop of Henle. Write their adverse effects and therapeutic use.
- Write the mechanism of action, adverse effects and uses of vincristine.
- Write the mechanism of action and uses of ampicillin.
- Describe the signal transduction pathway of MAPK kinases.
- What is RNA processing? Write the importance of tRNA and mRNA?
- Explain the process of cell cycle regulation.
- Write sources, mechanism of action and therapeutic uses of streptokinase and urokinase.
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SHORT ANSWERS 10 x 2 = 20 Marks
- Name four fibrinolytic agents.
- Mention four uses of thiazide diuretics.
- Mention any four blood schizonticides.
- What are probiotics? Give examples.
- Write uses of Glucocorticoids as immunosuppressants.
- Mode of action of Tetracyclines.
- Define therapeutic index.
- Explain the term chronic toxicity.
- Mention stages of mitosis.
- Name the types of gene therapies.
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