3 X 10 = 30 Marks
- Write an essay on Anticancer agents.
- What do you understand by Gene therapy? Explain in detail and discuss its clinical applications and recent advances.
- Discuss the stereochemistry and nomenclature of steroids and elucidate the structure of Testosterone.
- Elucidate the structure of Reserpine and confirm by its synthesis.
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SHORT ESSAY (Answer any Nine) 9 X 5 = 45 Marks
- Explain stereochemistry and nomenclature of alkaloids.
- Write a note on macrolide antibiotics.
- Elucidate the structure of cortisone.
- Discuss principle and method of RNA and DNA estimation.
- Give the structure and uses of the active constituents (at least 3) from a) Salacia reticulata b) Phyllanthus niruri c) Swertia chirata d) Curcuma longa
- How do 1HNMR, 13CNMR, IR and MS spectroscopy help in the characterization of Flavanoids?
- Write a note on Hybridoma technology.
- Discuss the isolation, biological activity and stereochemistry of Ephedrine.
- Write a note on newly developed cardiovascular drugs from natural origin.
- How would you differentiate the structure of steroids and alkaloids on the basis of IR?
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