Download RGUHS M.Pharm 1st Year 2020 5120 Chemistry Of Natural Products Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 1st Year (First Semester) 2020 5120 Chemistry Of Natural Products Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Semester M. Pharm Degree Examination - 17-Jan-2020
[Time: 3 Hours]
[Max. Marks: 75]
Chemistry of Natural Products
Q.P. CODE: 5120
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3X 10 = 30 Marks
1.
Discuss how new anticancer agents can be developed from natural products as a lead.
2.
What do you understand by Gene therapy? Explain in detail and discuss its clinical applications
and recent advances.
3.
Discuss the stereochemistry and nomenclature of steroids and elucidate the structure of
Testosterone.
4.
Elucidate the structure of Reserpine and confirm by its synthesis.
SHORT ESSAY (Answer any Nine)
9X 5 = 45 Marks
5.
Explain stereochemistry and nomenclature of alkaloids.
6.
Write note macrolide antibiotics.
7.
Elucidate the structure of cortisone.
8.
Discuss principle and method of RNA and DNA estimation.
9.
Give the structure and uses of the active constituents (at least 3) from a) Salacia reticulate
b) Phyllanthus niruri c) Swertia chirata d) Curmuma longa
10. How do 1HNMR, 13CNMR, IR and MS spectroscopy help in the characterization of Flavanoids?
11. Write a note on Hybridoma technology.
12. Discuss the isolation, biological activity and stereochemistry of Ephedrine.
13. Write a note on newly developed cardiovascular drugs from natural origin.
14. How would you differentiate the structure of steroids and alkaloids on the basis of IR.?
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