Download RGUHS M.Pharm 1st Year 2020 5112 Advanced Pharmaceutical Analysis Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) M.Pharm (Master of Pharmacy) 1st Year (First Semester) 2020 5112 Advanced Pharmaceutical Analysis Previous Question Paper

Rajiv Gandhi University of Health Sciences
First Semester M. Pharm Degree Examination - 20-Jan-2020
[Time: 3 Hours]
[Max. Marks: 75]
Advanced Pharmaceutical Analysis
Q.P. CODE: 5112
Your answers should be specific to the questions asked.
Draw neat, labeled diagrams wherever necessary.
LONG ESSAY (Answer any Three)
3 X 10 = 30 Marks
1.
Explain the principle and procedure involved in the assay of any one official drug each as per
IP for the following methods
a) Non-aqueous titrations b) potentiometric titrations
2.
Explain the principle and applications of the following reagents
a) Methyl -2 benzthiazolinone hydrazine(MBTH)
b) Para-dimethyl ?amino benzaldehyde (PDAB)
3.
Explain the the principle and procedure involved in quantitative estimation of drugs containing
following functional groups/Element.
a) Carboxyl group b) Halogen group
4.
Describe in detail the biological assay of Adsorbed Diphtheria vaccine.
SHORT ESSAY (Answer any Nine)
9 X 5 = 45 Marks
5.
Describe analysis of any one drug by RP-HPLC.
6.
Explain in brief analysis of any one drug by UV-extinction method.
7.
Explain the principle and applications of 2, 6 Dichloroquinone chlorimide in drug analysis?
8.
Write the procedure and applications of 1, 2 ? napthaquinone-4-sulfonate in drug analysis?
9.
Explain a method for determination of calcium.
10. Explain the principle and procedure of any one method for the estimation of Sodium.
11. Describe in brief biological assay of Oxytocin.
12. Write a brief note on biological assay of Heparin sodium IP.
13. Classify residual solvents and describe their permissible limits in drug products.
14. Write a brief note on potential sources of elemental impurities.
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