DU MPhil PhD in Bio Physics
Topic: BIOPHY MPHIL S2
1) A freely available web search engine to access full text of scholarly literature in variety of disciplines is:
[Question ID = 875]
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1. Wikipedia [Option ID = 3494]2. Google scholar [Option ID = 3495]
3. Shodhganga [Option ID = 3496]
4. ResearchGate [Option ID = 3497]
Correct Answer :
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Google scholar [Option ID = 3495]2) ICMR, a body involved in the management of biomedical research is:
[Question ID = 876]
1. Indian Council of Medical Research [Option ID = 3498]
2. International Council of Medical Research [Option ID = 3499]
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3. Indian Committee for Medical Research [Option ID = 3500]4. International Collaborative for Medical Research [Option ID = 3501]
Correct Answer :
Indian Council of Medical Research [Option ID = 3498]
3) Plagiarism refers to:
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[Question ID = 877]1. presenting someone else's ideas, thoughts, work as your own [Option ID = 3502]
2. illegally using the patented information for economic gains [Option ID = 3503]
3. not following ethical guidelines during research involving human subjects [Option ID = 3504]
4. not following ethical guidelines during research involving animals [Option ID = 3505]
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Correct Answer :presenting someone else's ideas, thoughts, work as your own [Option ID = 3502]
4) The set of precautions required to be followed in laboratory facilities when working with different biological agents are
called Biosafety levels. Currently how many levels are defined:
[Question ID = 878]
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1. 10 [Option ID = 3506]2. 4 [Option ID = 3507]
3. 5 [Option ID = 3508]
4. 11 [Option ID = 3509]
Correct Answer :
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4 [Option ID = 3507]5) Identify the correct order of a research project:
HYPOTHESIS (A), INFERENCES (B), EXPERIMENTATION (C), QUESTION (D), DATA ANALYSIS (E)
[Question ID = 879]
1. ADCBE [Option ID = 3510]
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2. DACEB [Option ID = 3511]3. ADCEB [Option ID = 3512]
4. DACBE [Option ID = 3513]
Correct Answer :
ADCEB [Option ID = 3512]
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6) Type I error in statistical hypothesis testing is?[Question ID = 880]
1. Acceptance of a test that produces false negative results [Option ID = 3514]
2. Acceptance of a test that produces false positive results [Option ID = 3515]
3. Acceptance of a test that has poor reproducibility [Option ID = 3516]
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4. Acceptance of a test that has poor precision [Option ID = 3517]Correct Answer :
Acceptance of a test that produces false positive results [Option ID = 3515]
7) If a series of 21 values are ordered in ascending order, the median would be
[Question ID = 881]
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1. The 11th value in the ordered series [Option ID = 3518]2. The mean between the 10th and 11th values [Option ID = 3519]
3. The mean between the 11th and 12thvalues [Option ID = 3520]
4. The 10th value in the ordered series [Option ID = 3521]
Correct Answer :
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The 11th value in the ordered series [Option ID = 3518]8) Which of the following is not a measure of central tendency?
[Question ID = 882]
1. Percentile [Option ID = 3522]
2. Quartile [Option ID = 3523]
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3. Standard deviation [Option ID = 3524]4. Mode [Option ID = 3525]
Correct Answer :
Standard deviation [Option ID = 3524]
9) Which one of these statistics is unaffected by outliers?
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[Question ID = 883]1. Mean [Option ID = 3526]
2. Interquartile range [Option ID = 3527]
3. Standard deviation [Option ID = 3528]
4. Range [Option ID = 3529]
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Correct Answer :Interquartile range [Option ID = 3527]
10) If 101 values are arranged in descending order, middle value will be
[Question ID = 884]
1. Arithmetic Mean [Option ID = 3530]
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2. Median [Option ID = 3531]3. 50th percentile [Option ID = 3532]
4. 51st percentile [Option ID = 3533]
Correct Answer :
Median [Option ID = 3531]
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11) Standard deviation is the measure of[Question ID = 885]
1. Chance [Option ID = 3534]
2. Central tendency [Option ID = 3535]
3. Deviation from mean value [Option ID = 3536]
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4. None [Option ID = 3537]Correct Answer :
Deviation from mean value [Option ID = 3536]
12) Strong correlation is signified by a correlation coefficient of:
[Question ID = 886]
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1. 0[Option ID = 3538]
2. 1
[Option ID = 3539]
3. > 1
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[Option ID = 3540]4. < 1
[Option ID = 3541]
Correct Answer :
1
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[Option ID = 3539]13) Mean, Medium and Mode are
[Question ID = 887]
1. Measure of dispersion [Option ID = 3542]
2. Measure association between two variables [Option ID = 3543]
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3. Test of significance [Option ID = 3544]4. Measure of central tendency [Option ID = 3545]
Correct Answer :
Measure of central tendency [Option ID = 3545]
14) Sample size depends on
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[Question ID = 888]1. Type of problem investigated
[Option ID = 3546]
2. Resources available
[Option ID = 3547]
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3. Required precision[Option ID = 3548]
4. All of these
[Option ID = 3549]
Correct Answer :
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All of these[Option ID = 3549]
15) When data is classified according to the magnitude it is called
[Question ID = 889]
1. Chronological data [Option ID = 3550]
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2. Qualitative data [Option ID = 3551]3. Quantitative data [Option ID = 3552]
4. Continuous data. [Option ID = 3553]
Correct Answer :
Quantitative data [Option ID = 3552]
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16) Continuous variables are represented by[Question ID = 890]
1. Histogram [Option ID = 3554]
2. Line diagram [Option ID = 3555]
3. Bar diagram [Option ID = 3556]
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4. Pie Chart. [Option ID = 3557]Correct Answer :
Histogram [Option ID = 3554]
17) Which statement is WRONG about BLAST
[Question ID = 891]
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1. It is a sequence database search tool [Option ID = 3558]2. It can be also used as an sequence alignment tool [Option ID = 3559]
3. Recently it is mostly used as a genome assembly tool [Option ID = 3560]
4. Homologous sequences can also be searched using it [Option ID = 3561]
Correct Answer :
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Recently it is mostly used as a genome assembly tool [Option ID = 3560]18) Ramachandran map is
[Question ID = 892]
1. A plot between Dihedral angles of side chains [Option ID = 3562]
2. A plot between psi and phi angles made between carbon backbone and side chains of an amino acid [Option ID = 3563]
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3. A plot between two Dihedral angles named as psi and phi [Option ID = 3564]4. A plot between phosphor diester bonds of C alpha chain [Option ID = 3565]
Correct Answer :
A plot between two Dihedral angles named as psi and phi [Option ID = 3564]
19) Which is NOT true for size exclusion chromatography?
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[Question ID = 893]1. The salt will first elute from the column while the protein will be retained [Option ID = 3566]
2. Separation of different compounds occurs according to their size/ hydrodynamic volume [Option ID = 3567]
3. It is based on the principle how efficiently the proteins penetrate the pores of the stationary phase [Option ID = 3568]
4. When size exclusion chromatography is performed using aqueous solvents, it is called gel filtration [Option ID = 3569]
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Correct Answer :When size exclusion chromatography is performed using aqueous solvents, it is called gel filtration [Option ID = 3569]
20) The branch of study dealing with Interaction of matter with Electromagnetic waves is called:
[Question ID = 894]
1. Spectroscopy [Option ID = 3570]
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2. Electromagnetism [Option ID = 3571]3. Radioactivity [Option ID = 3572]
4. Thermodynamics [Option ID = 3573]
Correct Answer :
Spectroscopy [Option ID = 3570]
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21) COVID19 is an infectious disease caused by a virus belonging to the family of:[Question ID = 895]
1. Influenza virus [Option ID = 3574]
2. Ebola virus [Option ID = 3575]
3. Corona virus [Option ID = 3576]
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4. Herpes Virus [Option ID = 3577]Correct Answer :
Corona virus [Option ID = 3576]
22) CD4 Surface marker is found in
[Question ID = 896]
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1. helper T cells [Option ID = 3578]2. cytotoxic T cells [Option ID = 3579]
3. neuronal cells [Option ID = 3580]
4. muscle cells [Option ID = 3581]
Correct Answer :
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helper T cells [Option ID = 3578]23) pI is routinely used to resolve proteins in which technique of electrophoresis:
[Question ID = 897]
1. SDS gel [Option ID = 3582]
2. Isoelectric focusing [Option ID = 3583]
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3. Native gel [Option ID = 3584]4. Acrylamide gel [Option ID = 3585]
Correct Answer :
Isoelectric focusing [Option ID = 3583]
24) Which is WRONG about the function of cyclins
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[Question ID = 898]1. They induce mitosis [Option ID = 3586]
2. with their periodic accumulation they control entry into M phase. [Option ID = 3587]
3. They function to induce meiosis [Option ID = 3588]
4. with their periodic destruction control exit from M phase. [Option ID = 3589]
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Correct Answer :They function to induce meiosis [Option ID = 3588]
25) ATP biosynthesis by utilization of the H+ gradient occurs in
[Question ID = 899]
1. Across the outer membrane of mitochondria and across the inner membrane of chloroplast [Option ID = 3590]
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2. Across the inner membrane of mitochondria and across the thylakoid membrane of chloroplast [Option ID = 3591]3. Within the matrix of mitochondria and across the inner membrane of chloroplast [Option ID = 3592]
4. Within the matrix of mitochondria and within the stroma of chloroplast [Option ID = 3593]
Correct Answer :
Across the inner membrane of mitochondria and across the thylakoid membrane of chloroplast [Option ID = 3591]
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26) Which of the following is a second messenger?[Question ID = 900]
1. Linear AMP [Option ID = 3594]
2. Diacylglycerol [Option ID = 3595]
3. Acetic Acid [Option ID = 3596]
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4. Phosphatidyl inositol [Option ID = 3597]Correct Answer :
Diacylglycerol [Option ID = 3595]
27) Sequence comparison of the following molecules is routinely used in phylogenetic identification and classification of
organisms:
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[Question ID = 901]1. 28S rRNA [Option ID = 3598]
2. 60S rRNA [Option ID = 3599]
3. 32S rRNA [Option ID = 3600]
4. 16S rRNA [Option ID = 3601]
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Correct Answer :16S rRNA [Option ID = 3601]
28) The human BRCA1 gene has been shown to be linked to the following cancers:
[Question ID = 902]
1. Breast cancer [Option ID = 3602]
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2. Lung cancer [Option ID = 3603]3. Prostrate cancer [Option ID = 3604]
4. Blood cancer [Option ID = 3605]
Correct Answer :
Breast cancer [Option ID = 3602]
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29) Liposomes are spherical vesicles commonly used for drug transport. They are made of[Question ID = 903]
1. Lipid monolayer [Option ID = 3606]
2. Lipid bilayer [Option ID = 3607]
3. Lipid multilayer [Option ID = 3608]
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4. Lipid monolayer with carbohydrate insertions [Option ID = 3609]Correct Answer :
Lipid bilayer [Option ID = 3607]
30) Which of the following will have the longest wavelength?
[Question ID = 904]
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1. Xrays [Option ID = 3610]2. Ultra Violet light [Option ID = 3611]
3. Infra Red radiations [Option ID = 3612]
4. Microwaves [Option ID = 3613]
Correct Answer :
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Microwaves [Option ID = 3613]31) Transmembrane proteins have sequences containing
[Question ID = 905]
1. Mostly serine and threonine which are embedded in membrane [Option ID = 3614]
2. Polar residues which are required for embedding in the membrane [Option ID = 3615]
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3. Hydrophilic residues which are embedded in membrane [Option ID = 3616]4. Hydrophobic residues which are embedded in membrane [Option ID = 3617]
Correct Answer :
Hydrophobic residues which are embedded in membrane [Option ID = 3617]
32) A coding region of a gene consists of 738 base pairs counting from start to stop codon. Calculate the number of peptide
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bonds of the protein coded from this gene. Five disulfide bonds are also present in the protein.[Question ID = 906]
1. 243 [Option ID = 3618]
2. 245 [Option ID = 3619]
3. 244 [Option ID = 3620]
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4. 246 [Option ID = 3621]Correct Answer :
244 [Option ID = 3620]
33) Paralogs are genes
[Question ID = 907]
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1. Which are originated due to gene duplication [Option ID = 3622]2. Which are originated due to speciation [Option ID = 3623]
3. Which are originated due to repliction fork slippage [Option ID = 3624]
4. Which doesn't show similarity with any other gene [Option ID = 3625]
Correct Answer :
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Which are originated due to gene duplication [Option ID = 3622]34) Which concentration of ethanol is utilized for disinfection?
[Question ID = 908]
1. 90% ethanol [Option ID = 3626]
2. 70% ethanol [Option ID = 3627]
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3. 50% ethanol [Option ID = 3628]4. 30% ethanol [Option ID = 3629]
Correct Answer :
70% ethanol [Option ID = 3627]
35) All of the following is NOT a primary databases
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[Question ID = 909]1. PDB [Option ID = 3630]
2. GeneBank [Option ID = 3631]
3. ENA [Option ID = 3632]
4. SWISSPROT [Option ID = 3633]
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Correct Answer :SWISSPROT [Option ID = 3633]
36) The computational methodology that tries to find the site of interaction between two molecules is called
[Question ID = 910]
1. Molecular matching [Option ID = 3634]
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2. Molecular docking [Option ID = 3635]3. Molecular fitting [Option ID = 3636]
4. Molecular affinity checking [Option ID = 3637]
Correct Answer :
Molecular docking [Option ID = 3635]
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37) White blood cells which are phagocytic in nature are[Question ID = 911]
1. Neutrophils and lymphocytes
[Option ID = 3638]
2. Neutrophils and macrophages
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[Option ID = 3639]3. Lymphocytes and macrophages
[Option ID = 3640]
4. Eosinophils and lymphocytes
[Option ID = 3641]
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Correct Answer :Lymphocytes and macrophages
[Option ID = 3640]
38) Which of the following is best method for long term storage of microbial samples
[Question ID = 912]
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1. lyophillization [Option ID = 3642]2. storage in a refrigerator in an agar plate [Option ID = 3643]
3. storage on a petriplate at room temperature [Option ID = 3644]
4. Storage in a freezer at 10degC [Option ID = 3645]
Correct Answer :
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lyophillization [Option ID = 3642]39) Ubiquitin is a
[Question ID = 913]
1. Protease [Option ID = 3646]
2. Component of the electron transport system [Option ID = 3647]
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3. Protein that tags another protein for proteolysis [Option ID = 3648]4. Protein kinase [Option ID = 3649]
Correct Answer :
Protein that tags another protein for proteolysis [Option ID = 3648]
40) Final common pathway for oxidation of carbohydrates, lipids and proteins is
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[Question ID = 914]1. Krebs cycle [Option ID = 3650]
2. Glycolysis [Option ID = 3651]
3. Pentose phosphate pathway [Option ID = 3652]
4. Electron transport chain [Option ID = 3653]
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Correct Answer :Electron transport chain [Option ID = 3653]
41) Migration of cancerous cells from the site of origin to other parts of the body forming secondary tumor is called
[Question ID = 915]
1. metastasis [Option ID = 3654]
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2. mitosis [Option ID = 3655]3. diapedesis [Option ID = 3656]
4. proliferation [Option ID = 3657]
Correct Answer :
metastasis [Option ID = 3654]
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42) The total number of triplet codons that code for an amino acid in human beings is[Question ID = 916]
1. 62 [Option ID = 3658]
2. 64 [Option ID = 3659]
3. 61 [Option ID = 3660]
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4. 66 [Option ID = 3661]Correct Answer :
61 [Option ID = 3660]
43) Which of the following is the best combination if one wishes to align more divergent sequences?
[Question ID = 917]
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1. Higher PAM or Lower BLOSUM [Option ID = 3662]2. Higher PAM or Higher BLOSUM [Option ID = 3663]
3. Lower PAM or Higher BLOSUM [Option ID = 3664]
4. Lower PAM or Lower BLOSUM [Option ID = 3665]
Correct Answer :
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Higher PAM or Lower BLOSUM [Option ID = 3662]44) Transmembrane proteins have sequences containing
[Question ID = 918]
1. Mostly serine and threonine which are embedded in membrane [Option ID = 3666]
2. Polar residues which are required for embedding in the membrane [Option ID = 3667]
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3. Hydrophilic residues which are embedded in membrane [Option ID = 3668]4. Hydrophobic residues which are embedded in membrane [Option ID = 3669]
Correct Answer :
Hydrophobic residues which are embedded in membrane [Option ID = 3669]
45) A competitive inhibitor
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[Question ID = 919]1. Is structural analogue of the substrate [Option ID = 3670]
2. Is structural analogue of the active site of the enzyme [Option ID = 3671]
3. Binds to a site other than active site of the enzyme [Option ID = 3672]
4. Is not at all related to the substrate [Option ID = 3673]
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Correct Answer :Is structural analogue of the substrate [Option ID = 3670]
46) Protein degradation inside cell is different from protein digestion because
[Question ID = 920]
1. Both require different cofactors [Option ID = 3674]
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2. Both processes are meant for maintaining protein quality [Option ID = 3675]3. Both processes require different signal sequences on all proteins [Option ID = 3676]
4. Degradation is for quality control and requires energy but digestion does not require energy [Option ID = 3677]
Correct Answer :
Degradation is for quality control and requires energy but digestion does not require energy [Option ID = 3677]
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47) If halflife of a radioactive material is 20 minutes, how much of a 1gm sample would be left after 60 minutes?[Question ID = 921]
1. 1.00 gm [Option ID = 3678]
2. 0.50 gm [Option ID = 3679]
3. 0.25 gm [Option ID = 3680]
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4. 0.125 gm [Option ID = 3681]Correct Answer :
0.125 gm [Option ID = 3681]
48) The two helical strands of DNA are held together by
[Question ID = 922]
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1. Covalent bonds [Option ID = 3682]2. Hydrogen bond [Option ID = 3683]
3. Disulphide bond [Option ID = 3684]
4. Phosphodiester bonds [Option ID = 3685]
Correct Answer :
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Hydrogen bond [Option ID = 3683]49) The alternative forms of a gene are known as
[Question ID = 923]
1. isomers [Option ID = 3686]
2. crossovers [Option ID = 3687]
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3. translocations. [Option ID = 3688]4. alleles [Option ID = 3689]
Correct Answer :
alleles [Option ID = 3689]
50) The functional native form of a human antibody exhibits which level of structure
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[Question ID = 924]1. Secondary structure [Option ID = 3690]
2. Tertiary Structure [Option ID = 3691]
3. Quaternary Structure [Option ID = 3692]
4. Primary Structure [Option ID = 3693]
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Correct Answer :Quaternary Structure [Option ID = 3692]