Download AKTU B-Tech 6th Sem 2015-2016 NBT 603 Bioinformatics Ii Question Paper

Download AKTU (Dr. A.P.J. Abdul Kalam Technical University (AKTU), formerly Uttar Pradesh Technical University (UPTU) B-Tech 6th Semester (Sixth Semester) 2015-2016 NBT 603 Bioinformatics Ii Question Paper

Printed Pages: 3 NBT?603
(Following Paper ID and Roll N 0. to be ?lled in your
Answer Books)
mmNd Illll llll
B..TECH.
Theory Examination (Semester?VI) 2015-16
BIOIN FORMATICS-ll
Time : 3 Hours Max. Marks .' 100
Section-A
1. Attempt all parts. All parts carry equal marks. Write
answer of each part in short. (2 X 10 = 20)
(a) What is genomic sequence annotation? Give some tools
for Gene and ()RF prediction.
(b) What is Microarray? How bioinformatics is applied to
analyse microarray data?
(c) What is machine leaming? Name some machine learning
approaches.
((1) What is a Decision Tree? Give example.
(e) What is computer simulation?
_ 0) RTO.
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(0 Describe the relation between statistics and machine (I) Explain Pharmacodynamics (Ef?cacy & Potency) &
learning. Pharmacokinetics (ADME).
(g) Explain the technique ofDocument clustering. (g) Explain the methods of clustering (Hierarchical and
K-mean).
(h) What is Lipinski's rule of five in insilicb drug
designing? (h) Describe Hidden Markov Model and one of its
application.
(i) What is the diffemce between Parametric and
Non-Parametric tests?
Section-C
(j) Explain Perl? What are Arrays, Hashes in Perl ?
Note : Attempt any two questions from this section.(15><2=30)
Section-B 3. Describe and discuss some molecular biology techniques and
their inference problems solved by the help of bioinformatics.
2. Attempt any ?ve parts. All parts cany equal marks :
?06:50) 4. What is force ?eld in molecular modeling? How is it helpful
. . . . 9
(a) What is simulate d annealing ? 1n study of molecular dynam1c Simulatlon.
(b) How is Arti?cial Neural Network helpful in solving 5- What is in silico drug designing? Explain Ligand and Structure
biological problems? based drug designing.
(0) Discuss and describe the Genetic Algorithm.
(d) Explain Natm?al Language Processing. Discuss its major
areas.
(e) Describe computer simulation techniques and its
types.
12) (3)
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