1)
2)
3)
4)
5)
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
Correct Answer :-
The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The Michaelis-Menten constant Km is
[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
2. Equivalent to the substrate concentration at which V
0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Compensation [Option ID = 11194]
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DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
0
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
7)
8)
9)
10)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
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2)
3)
5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
The high throughput screening [Option ID = 11186]
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
[Question ID = 2826]
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
0
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
0
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
6)
8)
9)
10)
11)
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
All of these [Option ID = 11232]
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
13)
14)
15)
16)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
[Question ID = 2807]
-1
[Option ID = 11226]
2. 1660 - 1770 cm
-1
3. 1915-2025 cm
-1
[Option ID = 11227]
4. 3400 - 3510 cm
[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
-1
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
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2)
3)
4)
5)
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
Correct Answer :-
The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The Michaelis-Menten constant Km is
[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
2. Equivalent to the substrate concentration at which V
0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Compensation [Option ID = 11194]
6)
7)
8)
10)
11)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
Correct Answer :-
All of these [Option ID = 11232]
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
12)
13)
15)
16)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
Correct Answer :-
GTPase [Option ID = 11205]
between
[Question ID = 2807]
1. 2240 -2360 cm
-1
2. 1660 - 1770 cm
-1
[Option ID = 11228]
3. 1915-2025 cm
[Option ID = 11227]
4. 3400 - 3510 cm
-1
[Option ID = 11225]
1660 - 1770 cm
-1
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
4. a base [Option ID = 11276]
Correct Answer :-
Cisplatin acts as an anti-cancer drug by
18)
19)
20)
22)
23)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
3. Formation of GG adducts [Option ID = 11267]
4. Formation of AA adducts [Option ID = 11268]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
A compound that acts as the starting point for drug design [Option ID = 11183]
Canscora decussata is more commonly known as [Question ID = 2824]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
4. amla [Option ID = 11293]
Correct Answer :-
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
[Question ID = 2789]
1. Arginine [Option ID = 11154]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
Correct Answer :-
Lysine [Option ID = 11153]
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
2. absolute refractory period [Option ID = 11117]
3. overshoot [Option ID = 11120]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
[Question ID = 2801]
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
4. Oct4, Sox2, Nanog [Option ID = 11201]
Correct Answer :-
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
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1)
2)
3)
5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
The high throughput screening [Option ID = 11186]
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
[Question ID = 2826]
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
0
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
0
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
6)
8)
9)
10)
11)
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
All of these [Option ID = 11232]
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
13)
14)
15)
16)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
[Question ID = 2807]
-1
[Option ID = 11226]
2. 1660 - 1770 cm
-1
3. 1915-2025 cm
-1
[Option ID = 11227]
4. 3400 - 3510 cm
[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
-1
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
18)
20)
21)
22)
23)
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
3. Formation of GG adducts [Option ID = 11267]
4. Formation of AA adducts [Option ID = 11268]
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
A compound that acts as the starting point for drug design [Option ID = 11183]
Canscora decussata is more commonly known as [Question ID = 2824]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
4. amla [Option ID = 11293]
Correct Answer :-
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
[Question ID = 2789]
1. Arginine [Option ID = 11154]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Correct Answer :-
Lysine [Option ID = 11153]
[Question ID = 2780]
1. spike potential [Option ID = 11119]
2. absolute refractory period [Option ID = 11117]
3. overshoot [Option ID = 11120]
Correct Answer :-
relative refractory period [Option ID = 11118]
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
[Question ID = 2801]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
4. Oct4, Sox2, Nanog [Option ID = 11201]
Correct Answer :-
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
24)
25)
27)
28)
1. 0.13 [Option ID = 11233]
2. 0.39 [Option ID = 11235]
4. 0.26 [Option ID = 11234]
Correct Answer :-
0.26 [Option ID = 11234]
White matter in brain lacks [Question ID = 2825]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
4. Oligodendrocytes [Option ID = 11298]
Correct Answer :-
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
these cells? [Question ID = 2803]
1. there will not be any X chromosome inactivation. [Option ID = 11209]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
Correct Answer :-
the Xist-deleted chromosome will always be active. [Option ID = 11211]
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental
results were obtained:
1. Protein moved more slowly on SDS PAGE
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
3. Mass spectrometric analysis showed that the modification was on serine
The modification that the protein undergoes is likely to be
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
3. Phosphorylation [Option ID = 11149]
4. ADP-ribosylation [Option ID = 11152]
Glycosylation [Option ID = 11150]
Esperamicin is an
[Question ID = 2813]
1. an anti-tumor antibiotic [Option ID = 11251]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
FirstRanker.com - FirstRanker's Choice
1)
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4)
5)
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What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
Correct Answer :-
0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
6)
7)
8)
9)
11)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
11230]
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
All of these [Option ID = 11232]
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
[Question ID = 2787]
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
Correct Answer :-
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
2. nicotinic receptors [Option ID = 11282]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
3. Me too drugs [Option ID = 11192]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
[Question ID = 2802]
12)
13)
14)
16)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
4. GDP kinase [Option ID = 11206]
Correct Answer :-
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
[Question ID = 2807]
1. 2240 -2360 cm
-1
[Option ID = 11226]
-1
[Option ID = 11228]
3. 1915-2025 cm
-1
4. 3400 - 3510 cm
-1
[Option ID = 11225]
Correct Answer :-
-1
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
3. cyclobutane [Option ID = 11261]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
cyclobutene [Option ID = 11262]
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
3. All three protein bands are of ?X? protein [Option ID = 11164]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
[Question ID = 2782]
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
Correct Answer :-
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
3. electrophile [Option ID = 11274]
4. a base [Option ID = 11276]
Correct Answer :-
electrophile [Option ID = 11274]
18)
19)
20)
21)
23)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
4. Formation of AA adducts [Option ID = 11268]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
Canscora decussata is more commonly known as [Question ID = 2824]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
Correct Answer :-
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
1. Arginine [Option ID = 11154]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Lysine [Option ID = 11153]
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
1. spike potential [Option ID = 11119]
3. overshoot [Option ID = 11120]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
relative refractory period [Option ID = 11118]
[Question ID = 2801]
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
Correct Answer :-
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
25)
26)
27)
28)
2. 0.39 [Option ID = 11235]
3. 0.52 [Option ID = 11236]
4. 0.26 [Option ID = 11234]
Correct Answer :-
White matter in brain lacks [Question ID = 2825]
1. Both Axons and Oligodendrocytes [Option ID = 11300]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
Correct Answer :-
Neuronal cell bodies [Option ID = 11299]
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
1. there will not be any X chromosome inactivation. [Option ID = 11209]
2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
the Xist-deleted chromosome will always be active. [Option ID = 11211]
Difference between systemic and glomerular capillaries is
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
4. surface area of glomerular capillary is more [Option ID = 11113]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
results were obtained:
1. Protein moved more slowly on SDS PAGE
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
3. Mass spectrometric analysis showed that the modification was on serine
The modification that the protein undergoes is likely to be
[Question ID = 2788]
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
4. ADP-ribosylation [Option ID = 11152]
Correct Answer :-
Glycosylation [Option ID = 11150]
Esperamicin is an
1. an anti-tumor antibiotic [Option ID = 11251]
2. anti-hypertensive drug [Option ID = 11249]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
30)
31)
32)
33)
Correct Answer :-
an anti-tumor antibiotic [Option ID = 11251]
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
2. x = 5.30g [Option ID = 11237]
3. x = 5.50g [Option ID = 11238]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
Ashwagandha is a natural product with
[Question ID = 2823]
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
4. anti-stress and anti-cancer activity [Option ID = 11289]
Correct Answer :-
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
1. receptor tyrosine kinase [Option ID = 11143]
2. src kinase [Option ID = 11144]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
apoptotic protein [Option ID = 11141]
Radiolabelling of DNA with P
32
radioisotope takes place at
1. phosphodiester bonds [Option ID = 11135]
2. none of these [Option ID = 11136]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
5? end of DNA [Option ID = 11133]
Tendency of cells to form colonies is increased by
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
3. inhibiting extracellular calcium [Option ID = 11129]
4. increasing extracellular calcium [Option ID = 11130]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
1. lactate to acetaldehyde [Option ID = 11246]
2. pyruvate to lactate [Option ID = 11245]
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4)
5)
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What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
Correct Answer :-
0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
6)
7)
8)
9)
11)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
11230]
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
All of these [Option ID = 11232]
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
[Question ID = 2787]
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
Correct Answer :-
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
2. nicotinic receptors [Option ID = 11282]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
3. Me too drugs [Option ID = 11192]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
[Question ID = 2802]
12)
13)
14)
16)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
4. GDP kinase [Option ID = 11206]
Correct Answer :-
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
[Question ID = 2807]
1. 2240 -2360 cm
-1
[Option ID = 11226]
-1
[Option ID = 11228]
3. 1915-2025 cm
-1
4. 3400 - 3510 cm
-1
[Option ID = 11225]
Correct Answer :-
-1
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
3. cyclobutane [Option ID = 11261]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
cyclobutene [Option ID = 11262]
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
3. All three protein bands are of ?X? protein [Option ID = 11164]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
[Question ID = 2782]
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
Correct Answer :-
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
3. electrophile [Option ID = 11274]
4. a base [Option ID = 11276]
Correct Answer :-
electrophile [Option ID = 11274]
18)
19)
20)
21)
23)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
4. Formation of AA adducts [Option ID = 11268]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
Canscora decussata is more commonly known as [Question ID = 2824]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
Correct Answer :-
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
1. Arginine [Option ID = 11154]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Lysine [Option ID = 11153]
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
1. spike potential [Option ID = 11119]
3. overshoot [Option ID = 11120]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
relative refractory period [Option ID = 11118]
[Question ID = 2801]
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
Correct Answer :-
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
25)
26)
27)
28)
2. 0.39 [Option ID = 11235]
3. 0.52 [Option ID = 11236]
4. 0.26 [Option ID = 11234]
Correct Answer :-
White matter in brain lacks [Question ID = 2825]
1. Both Axons and Oligodendrocytes [Option ID = 11300]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
Correct Answer :-
Neuronal cell bodies [Option ID = 11299]
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
1. there will not be any X chromosome inactivation. [Option ID = 11209]
2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
the Xist-deleted chromosome will always be active. [Option ID = 11211]
Difference between systemic and glomerular capillaries is
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
4. surface area of glomerular capillary is more [Option ID = 11113]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
results were obtained:
1. Protein moved more slowly on SDS PAGE
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
3. Mass spectrometric analysis showed that the modification was on serine
The modification that the protein undergoes is likely to be
[Question ID = 2788]
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
4. ADP-ribosylation [Option ID = 11152]
Correct Answer :-
Glycosylation [Option ID = 11150]
Esperamicin is an
1. an anti-tumor antibiotic [Option ID = 11251]
2. anti-hypertensive drug [Option ID = 11249]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
30)
31)
32)
33)
Correct Answer :-
an anti-tumor antibiotic [Option ID = 11251]
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
2. x = 5.30g [Option ID = 11237]
3. x = 5.50g [Option ID = 11238]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
Ashwagandha is a natural product with
[Question ID = 2823]
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
4. anti-stress and anti-cancer activity [Option ID = 11289]
Correct Answer :-
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
1. receptor tyrosine kinase [Option ID = 11143]
2. src kinase [Option ID = 11144]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
apoptotic protein [Option ID = 11141]
Radiolabelling of DNA with P
32
radioisotope takes place at
1. phosphodiester bonds [Option ID = 11135]
2. none of these [Option ID = 11136]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
5? end of DNA [Option ID = 11133]
Tendency of cells to form colonies is increased by
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
3. inhibiting extracellular calcium [Option ID = 11129]
4. increasing extracellular calcium [Option ID = 11130]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
1. lactate to acetaldehyde [Option ID = 11246]
2. pyruvate to lactate [Option ID = 11245]
35)
36)
38)
39)
3. pyruvate to acetaldehyde [Option ID = 11247]
4. acetaldehyde to acetic acid [Option ID = 11248]
pyruvate to lactate [Option ID = 11245]
How many pi molecular orbitals are present in hexatriene?
[Question ID = 2815]
1. 5 [Option ID = 11258]
3. 12 [Option ID = 11260]
4. 6 [Option ID = 11259]
Correct Answer :-
6 [Option ID = 11259]
[Question ID = 2820]
1. 4 [Option ID = 11279]
2. 2 [Option ID = 11277]
3. 3 [Option ID = 11278]
Correct Answer :-
4 [Option ID = 11279]
To determine the stability of protein ?A? under stimulus of hormone to cells, which of the following experiments should be carried
out?
1. Cell should be grown in the presence and absence of hormone. After different time intervals, protein is isolated and fractionated on SDS-PAGE and
western blot performed [Option ID = 11122]
2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present
[Option ID = 11124]
antibodies at different time intervals. [Option ID = 11121]
4. Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc).
Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
Correct Answer :-
etc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
In an experiment to detect DNA methylation in regulatory region of globin gene, which of the following method is recommended?
[Question ID = 2790]
1. PCR amplification and sequencing [Option ID = 11157]
3. Digestion with methylated sensitive restriction enzyme and electrophoresis [Option ID = 11158]
4. Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
Correct Answer :-
Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
[Question ID = 2804]
1. This a case of pseudo-genes [Option ID = 11215]
2. This is a case of pseudo-dominance [Option ID = 11216]
3. This is due to high rate of mutation [Option ID = 11214]
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5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
The high throughput screening [Option ID = 11186]
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
[Question ID = 2826]
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
0
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
0
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
6)
8)
9)
10)
11)
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
All of these [Option ID = 11232]
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
13)
14)
15)
16)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
[Question ID = 2807]
-1
[Option ID = 11226]
2. 1660 - 1770 cm
-1
3. 1915-2025 cm
-1
[Option ID = 11227]
4. 3400 - 3510 cm
[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
-1
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
18)
20)
21)
22)
23)
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
3. Formation of GG adducts [Option ID = 11267]
4. Formation of AA adducts [Option ID = 11268]
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
A compound that acts as the starting point for drug design [Option ID = 11183]
Canscora decussata is more commonly known as [Question ID = 2824]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
4. amla [Option ID = 11293]
Correct Answer :-
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
[Question ID = 2789]
1. Arginine [Option ID = 11154]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Correct Answer :-
Lysine [Option ID = 11153]
[Question ID = 2780]
1. spike potential [Option ID = 11119]
2. absolute refractory period [Option ID = 11117]
3. overshoot [Option ID = 11120]
Correct Answer :-
relative refractory period [Option ID = 11118]
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
[Question ID = 2801]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
4. Oct4, Sox2, Nanog [Option ID = 11201]
Correct Answer :-
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
24)
25)
27)
28)
1. 0.13 [Option ID = 11233]
2. 0.39 [Option ID = 11235]
4. 0.26 [Option ID = 11234]
Correct Answer :-
0.26 [Option ID = 11234]
White matter in brain lacks [Question ID = 2825]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
4. Oligodendrocytes [Option ID = 11298]
Correct Answer :-
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
these cells? [Question ID = 2803]
1. there will not be any X chromosome inactivation. [Option ID = 11209]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
Correct Answer :-
the Xist-deleted chromosome will always be active. [Option ID = 11211]
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental
results were obtained:
1. Protein moved more slowly on SDS PAGE
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
3. Mass spectrometric analysis showed that the modification was on serine
The modification that the protein undergoes is likely to be
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
3. Phosphorylation [Option ID = 11149]
4. ADP-ribosylation [Option ID = 11152]
Glycosylation [Option ID = 11150]
Esperamicin is an
[Question ID = 2813]
1. an anti-tumor antibiotic [Option ID = 11251]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
29)
30)
32)
33)
34)
Correct Answer :-
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
1. x = 6.00g [Option ID = 11240]
2. x = 5.30g [Option ID = 11237]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
x = 5.75g [Option ID = 11239]
Ashwagandha is a natural product with
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
3. the property of preventing amoebic infections [Option ID = 11291]
4. anti-stress and anti-cancer activity [Option ID = 11289]
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
[Question ID = 2786]
1. receptor tyrosine kinase [Option ID = 11143]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
Correct Answer :-
apoptotic protein [Option ID = 11141]
32
radioisotope takes place at
[Question ID = 2784]
1. phosphodiester bonds [Option ID = 11135]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
Correct Answer :-
5? end of DNA [Option ID = 11133]
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
2. inhibiting intracellular calcium [Option ID = 11131]
3. inhibiting extracellular calcium [Option ID = 11129]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
The enzyme lactate dehydrogenase converts [Question ID = 2812]
1. lactate to acetaldehyde [Option ID = 11246]
35)
36)
37)
38)
3. pyruvate to acetaldehyde [Option ID = 11247]
4. acetaldehyde to acetic acid [Option ID = 11248]
Correct Answer :-
pyruvate to lactate [Option ID = 11245]
[Question ID = 2815]
1. 5 [Option ID = 11258]
2. 4 [Option ID = 11257]
3. 12 [Option ID = 11260]
Correct Answer :-
6 [Option ID = 11259]
How many molecular orbitals are formed by combining 4 atomic orbitals?
[Question ID = 2820]
2. 2 [Option ID = 11277]
3. 3 [Option ID = 11278]
4. 8 [Option ID = 11280]
Correct Answer :-
To determine the stability of protein ?A? under stimulus of hormone to cells, which of the following experiments should be carried
out?
[Question ID = 2781]
1. Cell should be grown in the presence and absence of hormone. After different time intervals, protein is isolated and fractionated on SDS-PAGE and
2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present
[Option ID = 11124]
3. Extract total protein from the cell. In one tube add hormone and in another tube add buffer. Carry out western blotting for the protein A, using specific
antibodies at different time intervals. [Option ID = 11121]
Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
Correct Answer :-
Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs
etc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
[Question ID = 2790]
1. PCR amplification and sequencing [Option ID = 11157]
2. Restriction enzyme digestion and southern hybridization [Option ID = 11160]
3. Digestion with methylated sensitive restriction enzyme and electrophoresis [Option ID = 11158]
Correct Answer :-
Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
In a population from a recently discovered island in the Indian ocean, most of the people were of blood group O. This indicates that
[Question ID = 2804]
2. This is a case of pseudo-dominance [Option ID = 11216]
3. This is due to high rate of mutation [Option ID = 11214]
4. Blood group O is a truly dominant allele [Option ID = 11213]
40)
42)
43)
44)
45)
This is a case of pseudo-dominance [Option ID = 11216]
Which phospholipid inhibits the release of Cytochrome c from the mitochondria?
[Question ID = 2785]
1. Cardiolipin [Option ID = 11139]
3. Phosphatidyl choline [Option ID = 11138]
4. None of these [Option ID = 11140]
Correct Answer :-
Cardiolipin [Option ID = 11139]
[Question ID = 2800]
1. IL-1 [Option ID = 11199]
2. IL-17 [Option ID = 11200]
3. IL-10 [Option ID = 11197]
Correct Answer :-
IL-17 [Option ID = 11200]
Which of the following is true, if carbonyl (C=O) group of i
th
[Question ID = 2806]
1. n=4 is a ?- helix [Option ID = 11222]
2. n=3 is an alpha helix [Option ID = 11223]
3. n=2, peptide degenerates to a non chiral, 2, 2
helical ribbon [Option ID = 11221]
4. n=5 is a 3.6
13
helix [Option ID = 11224]
n=2, peptide degenerates to a non chiral, 2, 2
7
helical ribbon [Option ID = 11221]
Which of the following is NOT a part of the primary proteins structure?
1. The disulphide linkages [Option ID = 11174]
2. The amino acid sequences [Option ID = 11173]
3. The conformation of the polypeptide backbone [Option ID = 11176]
4. The planar nature of the amide linkage [Option ID = 11175]
The disulphide linkages [Option ID = 11174]
Which of the following metal ions is used for the treatment of arthritis?
[Question ID = 2818]
1. Magnesium [Option ID = 11272]
3. Gold [Option ID = 11271]
4. Silver [Option ID = 11269]
Correct Answer :-
Gold [Option ID = 11271]
[Question ID = 2814]
FirstRanker.com - FirstRanker's Choice
1)
2)
4)
5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
0
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
7)
8)
9)
10)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
12)
13)
14)
15)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
Correct Answer :-
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
1. 2240 -2360 cm
-1
[Option ID = 11226]
2. 1660 - 1770 cm
[Option ID = 11228]
3. 1915-2025 cm
-1
[Option ID = 11227]
-1
[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
4. a base [Option ID = 11276]
Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
19)
20)
21)
22)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
3. Formation of GG adducts [Option ID = 11267]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
A compound that acts as the starting point for drug design [Option ID = 11183]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
4. amla [Option ID = 11293]
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
[Question ID = 2789]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Correct Answer :-
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
1. spike potential [Option ID = 11119]
2. absolute refractory period [Option ID = 11117]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
relative refractory period [Option ID = 11118]
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
4. Oct4, Sox2, Nanog [Option ID = 11201]
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
24)
26)
27)
28)
1. 0.13 [Option ID = 11233]
3. 0.52 [Option ID = 11236]
4. 0.26 [Option ID = 11234]
Correct Answer :-
0.26 [Option ID = 11234]
1. Both Axons and Oligodendrocytes [Option ID = 11300]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
4. Oligodendrocytes [Option ID = 11298]
Neuronal cell bodies [Option ID = 11299]
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
these cells? [Question ID = 2803]
2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
Correct Answer :-
Difference between systemic and glomerular capillaries is
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
4. surface area of glomerular capillary is more [Option ID = 11113]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental
1. Protein moved more slowly on SDS PAGE
3. Mass spectrometric analysis showed that the modification was on serine
[Question ID = 2788]
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
3. Phosphorylation [Option ID = 11149]
Correct Answer :-
Glycosylation [Option ID = 11150]
Esperamicin is an
[Question ID = 2813]
2. anti-hypertensive drug [Option ID = 11249]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
29)
31)
32)
33)
34)
an anti-tumor antibiotic [Option ID = 11251]
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
1. x = 6.00g [Option ID = 11240]
3. x = 5.50g [Option ID = 11238]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
x = 5.75g [Option ID = 11239]
[Question ID = 2823]
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
3. the property of preventing amoebic infections [Option ID = 11291]
Correct Answer :-
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
[Question ID = 2786]
2. src kinase [Option ID = 11144]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
Correct Answer :-
Radiolabelling of DNA with P
32
radioisotope takes place at
[Question ID = 2784]
2. none of these [Option ID = 11136]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
Correct Answer :-
Tendency of cells to form colonies is increased by
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
2. inhibiting intracellular calcium [Option ID = 11131]
4. increasing extracellular calcium [Option ID = 11130]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
The enzyme lactate dehydrogenase converts [Question ID = 2812]
2. pyruvate to lactate [Option ID = 11245]
35)
36)
37)
39)
3. pyruvate to acetaldehyde [Option ID = 11247]
4. acetaldehyde to acetic acid [Option ID = 11248]
Correct Answer :-
How many pi molecular orbitals are present in hexatriene?
[Question ID = 2815]
1. 5 [Option ID = 11258]
2. 4 [Option ID = 11257]
4. 6 [Option ID = 11259]
Correct Answer :-
6 [Option ID = 11259]
How many molecular orbitals are formed by combining 4 atomic orbitals?
1. 4 [Option ID = 11279]
2. 2 [Option ID = 11277]
3. 3 [Option ID = 11278]
4. 8 [Option ID = 11280]
4 [Option ID = 11279]
To determine the stability of protein ?A? under stimulus of hormone to cells, which of the following experiments should be carried
out?
[Question ID = 2781]
western blot performed [Option ID = 11122]
2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present
[Option ID = 11124]
3. Extract total protein from the cell. In one tube add hormone and in another tube add buffer. Carry out western blotting for the protein A, using specific
4. Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc).
Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
Correct Answer :-
Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs
In an experiment to detect DNA methylation in regulatory region of globin gene, which of the following method is recommended?
[Question ID = 2790]
1. PCR amplification and sequencing [Option ID = 11157]
2. Restriction enzyme digestion and southern hybridization [Option ID = 11160]
4. Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
Correct Answer :-
Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
In a population from a recently discovered island in the Indian ocean, most of the people were of blood group O. This indicates that
1. This a case of pseudo-genes [Option ID = 11215]
2. This is a case of pseudo-dominance [Option ID = 11216]
3. This is due to high rate of mutation [Option ID = 11214]
4. Blood group O is a truly dominant allele [Option ID = 11213]
41)
42)
43)
44)
Correct Answer :-
This is a case of pseudo-dominance [Option ID = 11216]
Which phospholipid inhibits the release of Cytochrome c from the mitochondria?
[Question ID = 2785]
2. Phosphatidyl serine [Option ID = 11137]
3. Phosphatidyl choline [Option ID = 11138]
4. None of these [Option ID = 11140]
Correct Answer :-
Which cytokine is primarily responsible for auto immune response?
[Question ID = 2800]
1. IL-1 [Option ID = 11199]
2. IL-17 [Option ID = 11200]
4. IL-5 [Option ID = 11198]
Correct Answer :-
IL-17 [Option ID = 11200]
Which of the following is true, if carbonyl (C=O) group of i
residue in a polypeptide chain hydrogen bonds with i+n residue, where
[Question ID = 2806]
1. n=4 is a ?- helix [Option ID = 11222]
2. n=3 is an alpha helix [Option ID = 11223]
7
helical ribbon [Option ID = 11221]
4. n=5 is a 3.6
13
Correct Answer :-
n=2, peptide degenerates to a non chiral, 2, 2
7
helical ribbon [Option ID = 11221]
[Question ID = 2794]
1. The disulphide linkages [Option ID = 11174]
2. The amino acid sequences [Option ID = 11173]
3. The conformation of the polypeptide backbone [Option ID = 11176]
Correct Answer :-
The disulphide linkages [Option ID = 11174]
Which of the following metal ions is used for the treatment of arthritis?
[Question ID = 2818]
2. Copper [Option ID = 11270]
3. Gold [Option ID = 11271]
4. Silver [Option ID = 11269]
Correct Answer :-
Which of the following statements is correct?
[Question ID = 2814]
46)
47)
49)
50)
1. DNA polymerase is DNA alkylator [Option ID = 11256]
2. Netropsin is a major groove binder [Option ID = 11255]
4. Ethidium bromide intercalates with DNA [Option ID = 11254]
Correct Answer :-
Ethidium bromide intercalates with DNA [Option ID = 11254]
Which of the following statements is false about the NMR experiment?
1. The energy required to flip the spin of a system is in the infrared region of the electromagnetic spectrum [Option ID = 11165]
2. The energy difference between two spin states depends on the strength of the magnetic field [Option ID = 11166]
3. When energy absorption occurs, the nuclei are said to be in resonance with the electromagnetic radiation [Option ID = 11167]
4. When a proton is aligned with the magnetic field, its energy is lower than when its is aligned against the magnetic field [Option ID = 11168]
The energy required to flip the spin of a system is in the infrared region of the electromagnetic spectrum [Option ID = 11165]
Which of the following compounds has the most de-shielded proton?
[Question ID = 2793]
1. CH
I [Option ID = 11170]
2. CH
3
F [Option ID = 11172]
3
Cl [Option ID = 11169]
4. CH
3
Correct Answer :-
CH
3
F [Option ID = 11172]
[Question ID = 2822]
1. C
2
axis of symmetry [Option ID = 11286]
3
axis of symmetry [Option ID = 11285]
3. S
2
4. Center of symmetry [Option ID = 11288]
Correct Answer :-
C
3
Which of these can not pass through the glomerular capillaries under normal condition?
[Question ID = 2777]
1. Albumin [Option ID = 11108]
2. Water [Option ID = 11105]
4. Potassium [Option ID = 11107]
Correct Answer :-
Albumin [Option ID = 11108]
Benzotriazole contains [Question ID = 2811]
2. three nitrogen atoms [Option ID = 11243]
3. three nitro groups [Option ID = 11244]
4. two oxygen and one nitrogen atom [Option ID = 11242]
Correct Answer :-
FirstRanker.com - FirstRanker's Choice
2)
3)
4)
5)
--- Content provided by FirstRanker.com ---
DU PhD In Biomedcal SciencesTopic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
--- Content provided by FirstRanker.com ---
2. 5% [Option ID = 11109]3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
--- Content provided by FirstRanker.com ---
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
--- Content provided by FirstRanker.com ---
4. Multi-screening [Option ID = 11187]Correct Answer :-
The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
--- Content provided by FirstRanker.com ---
1. The association of two or more peptide chain [Option ID = 11177]2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
--- Content provided by FirstRanker.com ---
The association of two or more peptide chain [Option ID = 11177]The Michaelis-Menten constant Km is
[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is one half of Vmax [Option ID = 11303]2. Equivalent to the substrate concentration at which V
0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
--- Content provided by FirstRanker.com ---
Correct Answer :-Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
--- Content provided by FirstRanker.com ---
[Question ID = 2799]1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
--- Content provided by FirstRanker.com ---
Correct Answer :-Compensation [Option ID = 11194]
FirstRanker.com - FirstRanker's Choice
1)
2)
--- Content provided by FirstRanker.com ---
3)4)
5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
--- Content provided by FirstRanker.com ---
What fraction of total blood volume is present in the capillaries at any given time?[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
--- Content provided by FirstRanker.com ---
4. 15% [Option ID = 11111]Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
--- Content provided by FirstRanker.com ---
1. The high throughput screening [Option ID = 11186]2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
--- Content provided by FirstRanker.com ---
The high throughput screening [Option ID = 11186]What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
--- Content provided by FirstRanker.com ---
3. Partial denaturation [Option ID = 11179]4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
--- Content provided by FirstRanker.com ---
[Question ID = 2826]1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
--- Content provided by FirstRanker.com ---
4. Equivalent to the substrate concentration at which V0
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
--- Content provided by FirstRanker.com ---
2. Compensation [Option ID = 11194]3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
--- Content provided by FirstRanker.com ---
6)7)
8)
9)
10)
--- Content provided by FirstRanker.com ---
11)The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
--- Content provided by FirstRanker.com ---
11230]2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
--- Content provided by FirstRanker.com ---
All of these [Option ID = 11232]The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
--- Content provided by FirstRanker.com ---
3. each ? and ? pair can assume two different conformation [Option ID = 11218]4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
--- Content provided by FirstRanker.com ---
[Question ID = 2787]1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
--- Content provided by FirstRanker.com ---
Correct Answer :-inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
--- Content provided by FirstRanker.com ---
2. nicotinic receptors [Option ID = 11282]3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
--- Content provided by FirstRanker.com ---
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discoveryof a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
--- Content provided by FirstRanker.com ---
3. Me too drugs [Option ID = 11192]4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
--- Content provided by FirstRanker.com ---
[Question ID = 2802]FirstRanker.com - FirstRanker's Choice
1)
2)
3)
--- Content provided by FirstRanker.com ---
4)5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
--- Content provided by FirstRanker.com ---
[Question ID = 2778]1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
--- Content provided by FirstRanker.com ---
Correct Answer :-5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
--- Content provided by FirstRanker.com ---
2. Robotic testing [Option ID = 11185]3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
The high throughput screening [Option ID = 11186]
--- Content provided by FirstRanker.com ---
What does quaternary structure of a protein involve?[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
--- Content provided by FirstRanker.com ---
4. Random coil alternating with alpha helix [Option ID = 11180]Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
[Question ID = 2826]
--- Content provided by FirstRanker.com ---
1. Equivalent to the substrate concentration at which V0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is equal to Vmax [Option ID = 11301]3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is one half of Vmax [Option ID = 11303]The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
--- Content provided by FirstRanker.com ---
3. Binary correction [Option ID = 11196]4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
6)
--- Content provided by FirstRanker.com ---
7)8)
9)
10)
11)
--- Content provided by FirstRanker.com ---
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nucleardistances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
--- Content provided by FirstRanker.com ---
2. All of these [Option ID = 11232]3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
All of these [Option ID = 11232]
--- Content provided by FirstRanker.com ---
The Ramachandran plot illustrates the fact that[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
--- Content provided by FirstRanker.com ---
4. each ? and ? pair can assume any conformation [Option ID = 11220]Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
--- Content provided by FirstRanker.com ---
1. none of these [Option ID = 11148]2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
--- Content provided by FirstRanker.com ---
inhibits receptor tyrosine kinase activation [Option ID = 11145]Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
--- Content provided by FirstRanker.com ---
3. muscarinic receptors [Option ID = 11281]4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
--- Content provided by FirstRanker.com ---
of a complex structure which is likely to be different from other previously discovered?[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
--- Content provided by FirstRanker.com ---
4. Combinatorial chemistry [Option ID = 11189]Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
--- Content provided by FirstRanker.com ---
12)13)
14)
15)
16)
--- Content provided by FirstRanker.com ---
17)1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
--- Content provided by FirstRanker.com ---
Correct Answer :-GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
[Question ID = 2807]
--- Content provided by FirstRanker.com ---
1. 2240 -2360 cm-1
[Option ID = 11226]
2. 1660 - 1770 cm
-1
--- Content provided by FirstRanker.com ---
[Option ID = 11228]3. 1915-2025 cm
-1
[Option ID = 11227]
4. 3400 - 3510 cm
--- Content provided by FirstRanker.com ---
-1[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
-1
--- Content provided by FirstRanker.com ---
[Option ID = 11228]Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
--- Content provided by FirstRanker.com ---
4. cyclobutene [Option ID = 11262]Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
--- Content provided by FirstRanker.com ---
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [QuestionID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
--- Content provided by FirstRanker.com ---
4. Degradation product of Protein ?X? [Option ID = 11163]Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
--- Content provided by FirstRanker.com ---
1. All these condition [Option ID = 11128]2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
--- Content provided by FirstRanker.com ---
only lactose is present [Option ID = 11127]Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
--- Content provided by FirstRanker.com ---
4. a base [Option ID = 11276]Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
FirstRanker.com - FirstRanker's Choice
--- Content provided by FirstRanker.com ---
1)2)
3)
4)
5)
--- Content provided by FirstRanker.com ---
DU PhD In Biomedcal SciencesTopic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
--- Content provided by FirstRanker.com ---
2. 5% [Option ID = 11109]3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
--- Content provided by FirstRanker.com ---
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
--- Content provided by FirstRanker.com ---
4. Multi-screening [Option ID = 11187]Correct Answer :-
The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
--- Content provided by FirstRanker.com ---
1. The association of two or more peptide chain [Option ID = 11177]2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
--- Content provided by FirstRanker.com ---
The association of two or more peptide chain [Option ID = 11177]The Michaelis-Menten constant Km is
[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is one half of Vmax [Option ID = 11303]2. Equivalent to the substrate concentration at which V
0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
--- Content provided by FirstRanker.com ---
Correct Answer :-Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
--- Content provided by FirstRanker.com ---
[Question ID = 2799]1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
--- Content provided by FirstRanker.com ---
Correct Answer :-Compensation [Option ID = 11194]
6)
7)
8)
--- Content provided by FirstRanker.com ---
9)10)
11)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
--- Content provided by FirstRanker.com ---
[Question ID = 2808]1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
--- Content provided by FirstRanker.com ---
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]Correct Answer :-
All of these [Option ID = 11232]
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
--- Content provided by FirstRanker.com ---
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
--- Content provided by FirstRanker.com ---
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
--- Content provided by FirstRanker.com ---
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
--- Content provided by FirstRanker.com ---
[Question ID = 2821]1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
--- Content provided by FirstRanker.com ---
Correct Answer :-GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
--- Content provided by FirstRanker.com ---
1. Screening plant extract [Option ID = 11191]2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Screening plant extract [Option ID = 11191]Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
12)
13)
--- Content provided by FirstRanker.com ---
14)15)
16)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
--- Content provided by FirstRanker.com ---
2. GTPase [Option ID = 11205]3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
Correct Answer :-
GTPase [Option ID = 11205]
--- Content provided by FirstRanker.com ---
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peakbetween
[Question ID = 2807]
1. 2240 -2360 cm
-1
--- Content provided by FirstRanker.com ---
[Option ID = 11226]2. 1660 - 1770 cm
-1
[Option ID = 11228]
3. 1915-2025 cm
--- Content provided by FirstRanker.com ---
-1[Option ID = 11227]
4. 3400 - 3510 cm
-1
[Option ID = 11225]
--- Content provided by FirstRanker.com ---
Correct Answer :-1660 - 1770 cm
-1
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
--- Content provided by FirstRanker.com ---
1. methyl cyclopropane [Option ID = 11263]2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
--- Content provided by FirstRanker.com ---
cyclobutene [Option ID = 11262]Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
--- Content provided by FirstRanker.com ---
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
--- Content provided by FirstRanker.com ---
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
--- Content provided by FirstRanker.com ---
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]4. only lactose is present [Option ID = 11127]
Correct Answer :-
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
--- Content provided by FirstRanker.com ---
1. nucleophile [Option ID = 11273]2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
4. a base [Option ID = 11276]
Correct Answer :-
--- Content provided by FirstRanker.com ---
electrophile [Option ID = 11274]Cisplatin acts as an anti-cancer drug by
18)
19)
20)
--- Content provided by FirstRanker.com ---
21)22)
23)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
--- Content provided by FirstRanker.com ---
2. Formation of hydroxyl radicals [Option ID = 11266]3. Formation of GG adducts [Option ID = 11267]
4. Formation of AA adducts [Option ID = 11268]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
--- Content provided by FirstRanker.com ---
What you mean by a lead compound in drug discovery? [Question ID = 2796]1. A compound that acts as the starting point for drug design [Option ID = 11183]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
--- Content provided by FirstRanker.com ---
Correct Answer :-A compound that acts as the starting point for drug design [Option ID = 11183]
Canscora decussata is more commonly known as [Question ID = 2824]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
--- Content provided by FirstRanker.com ---
3. bel [Option ID = 11296]4. amla [Option ID = 11293]
Correct Answer :-
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
--- Content provided by FirstRanker.com ---
involved in acetylation?[Question ID = 2789]
1. Arginine [Option ID = 11154]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
--- Content provided by FirstRanker.com ---
4. Lysine [Option ID = 11153]Correct Answer :-
Lysine [Option ID = 11153]
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
--- Content provided by FirstRanker.com ---
1. spike potential [Option ID = 11119]2. absolute refractory period [Option ID = 11117]
3. overshoot [Option ID = 11120]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
--- Content provided by FirstRanker.com ---
relative refractory period [Option ID = 11118]Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
[Question ID = 2801]
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
--- Content provided by FirstRanker.com ---
3. Oct4, Sox2, CDX2 [Option ID = 11202]4. Oct4, Sox2, Nanog [Option ID = 11201]
Correct Answer :-
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
--- Content provided by FirstRanker.com ---
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]FirstRanker.com - FirstRanker's Choice
1)
2)
3)
--- Content provided by FirstRanker.com ---
4)5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
--- Content provided by FirstRanker.com ---
[Question ID = 2778]1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
--- Content provided by FirstRanker.com ---
Correct Answer :-5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
--- Content provided by FirstRanker.com ---
2. Robotic testing [Option ID = 11185]3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
The high throughput screening [Option ID = 11186]
--- Content provided by FirstRanker.com ---
What does quaternary structure of a protein involve?[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
--- Content provided by FirstRanker.com ---
4. Random coil alternating with alpha helix [Option ID = 11180]Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
[Question ID = 2826]
--- Content provided by FirstRanker.com ---
1. Equivalent to the substrate concentration at which V0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is equal to Vmax [Option ID = 11301]3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is one half of Vmax [Option ID = 11303]The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
--- Content provided by FirstRanker.com ---
3. Binary correction [Option ID = 11196]4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
6)
--- Content provided by FirstRanker.com ---
7)8)
9)
10)
11)
--- Content provided by FirstRanker.com ---
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nucleardistances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
--- Content provided by FirstRanker.com ---
2. All of these [Option ID = 11232]3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
All of these [Option ID = 11232]
--- Content provided by FirstRanker.com ---
The Ramachandran plot illustrates the fact that[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
--- Content provided by FirstRanker.com ---
4. each ? and ? pair can assume any conformation [Option ID = 11220]Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
--- Content provided by FirstRanker.com ---
1. none of these [Option ID = 11148]2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
--- Content provided by FirstRanker.com ---
inhibits receptor tyrosine kinase activation [Option ID = 11145]Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
--- Content provided by FirstRanker.com ---
3. muscarinic receptors [Option ID = 11281]4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
--- Content provided by FirstRanker.com ---
of a complex structure which is likely to be different from other previously discovered?[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
--- Content provided by FirstRanker.com ---
4. Combinatorial chemistry [Option ID = 11189]Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
--- Content provided by FirstRanker.com ---
12)13)
14)
15)
16)
--- Content provided by FirstRanker.com ---
17)1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
--- Content provided by FirstRanker.com ---
Correct Answer :-GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
[Question ID = 2807]
--- Content provided by FirstRanker.com ---
1. 2240 -2360 cm-1
[Option ID = 11226]
2. 1660 - 1770 cm
-1
--- Content provided by FirstRanker.com ---
[Option ID = 11228]3. 1915-2025 cm
-1
[Option ID = 11227]
4. 3400 - 3510 cm
--- Content provided by FirstRanker.com ---
-1[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
-1
--- Content provided by FirstRanker.com ---
[Option ID = 11228]Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
--- Content provided by FirstRanker.com ---
4. cyclobutene [Option ID = 11262]Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
--- Content provided by FirstRanker.com ---
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [QuestionID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
--- Content provided by FirstRanker.com ---
4. Degradation product of Protein ?X? [Option ID = 11163]Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
--- Content provided by FirstRanker.com ---
1. All these condition [Option ID = 11128]2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
--- Content provided by FirstRanker.com ---
only lactose is present [Option ID = 11127]Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
--- Content provided by FirstRanker.com ---
4. a base [Option ID = 11276]Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
18)
--- Content provided by FirstRanker.com ---
19)20)
21)
22)
23)
--- Content provided by FirstRanker.com ---
[Question ID = 2817]1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
3. Formation of GG adducts [Option ID = 11267]
4. Formation of AA adducts [Option ID = 11268]
--- Content provided by FirstRanker.com ---
Correct Answer :-Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
--- Content provided by FirstRanker.com ---
3. A drug containing the element lead [Option ID = 11181]4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
A compound that acts as the starting point for drug design [Option ID = 11183]
Canscora decussata is more commonly known as [Question ID = 2824]
--- Content provided by FirstRanker.com ---
1. shankhpushpi [Option ID = 11295]2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
4. amla [Option ID = 11293]
Correct Answer :-
--- Content provided by FirstRanker.com ---
shankhpushpi [Option ID = 11295]Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
[Question ID = 2789]
1. Arginine [Option ID = 11154]
--- Content provided by FirstRanker.com ---
2. Asparagine [Option ID = 11155]3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Correct Answer :-
Lysine [Option ID = 11153]
--- Content provided by FirstRanker.com ---
A stronger than normal stimulus can cause excitation of nerve or muscle during[Question ID = 2780]
1. spike potential [Option ID = 11119]
2. absolute refractory period [Option ID = 11117]
3. overshoot [Option ID = 11120]
--- Content provided by FirstRanker.com ---
4. relative refractory period [Option ID = 11118]Correct Answer :-
relative refractory period [Option ID = 11118]
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
[Question ID = 2801]
--- Content provided by FirstRanker.com ---
1. Sox2, CDX2, Nanog [Option ID = 11204]2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
4. Oct4, Sox2, Nanog [Option ID = 11201]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Oct4, Sox2, Nanog [Option ID = 11201]Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
24)
25)
--- Content provided by FirstRanker.com ---
26)27)
28)
1. 0.13 [Option ID = 11233]
2. 0.39 [Option ID = 11235]
--- Content provided by FirstRanker.com ---
3. 0.52 [Option ID = 11236]4. 0.26 [Option ID = 11234]
Correct Answer :-
0.26 [Option ID = 11234]
White matter in brain lacks [Question ID = 2825]
--- Content provided by FirstRanker.com ---
1. Both Axons and Oligodendrocytes [Option ID = 11300]2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
4. Oligodendrocytes [Option ID = 11298]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Neuronal cell bodies [Option ID = 11299]Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
these cells? [Question ID = 2803]
1. there will not be any X chromosome inactivation. [Option ID = 11209]
--- Content provided by FirstRanker.com ---
2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
Correct Answer :-
the Xist-deleted chromosome will always be active. [Option ID = 11211]
--- Content provided by FirstRanker.com ---
Difference between systemic and glomerular capillaries is[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
--- Content provided by FirstRanker.com ---
4. surface area of glomerular capillary is more [Option ID = 11113]Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental
results were obtained:
--- Content provided by FirstRanker.com ---
1. Protein moved more slowly on SDS PAGE
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
--- Content provided by FirstRanker.com ---
3. Mass spectrometric analysis showed that the modification was on serine
The modification that the protein undergoes is likely to be
--- Content provided by FirstRanker.com ---
[Question ID = 2788]1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
3. Phosphorylation [Option ID = 11149]
4. ADP-ribosylation [Option ID = 11152]
--- Content provided by FirstRanker.com ---
Correct Answer :-Glycosylation [Option ID = 11150]
Esperamicin is an
[Question ID = 2813]
1. an anti-tumor antibiotic [Option ID = 11251]
--- Content provided by FirstRanker.com ---
2. anti-hypertensive drug [Option ID = 11249]3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
FirstRanker.com - FirstRanker's Choice
1)
--- Content provided by FirstRanker.com ---
2)3)
4)
5)
DU PhD In Biomedcal Sciences
--- Content provided by FirstRanker.com ---
Topic:- DU_J18_PHD_BIOSCI_Topic01What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
--- Content provided by FirstRanker.com ---
3. 20% [Option ID = 11110]4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
--- Content provided by FirstRanker.com ---
[Question ID = 2797]1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
--- Content provided by FirstRanker.com ---
Correct Answer :-The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
--- Content provided by FirstRanker.com ---
2. The complete three-dimensional conformation [Option ID = 11178]3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
--- Content provided by FirstRanker.com ---
The Michaelis-Menten constant Km is[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
--- Content provided by FirstRanker.com ---
2. Equivalent to the substrate concentration at which V0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is one fourth Vmax [Option ID = 11304]4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Equivalent to the substrate concentration at which V0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
--- Content provided by FirstRanker.com ---
1. Voltage adjustment [Option ID = 11195]2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Compensation [Option ID = 11194]6)
7)
8)
9)
--- Content provided by FirstRanker.com ---
10)11)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
--- Content provided by FirstRanker.com ---
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =11230]
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
--- Content provided by FirstRanker.com ---
Correct Answer :-All of these [Option ID = 11232]
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
--- Content provided by FirstRanker.com ---
2. the peptide bond is non-planar [Option ID = 11217]3. each ? and ? pair can assume two different conformation [Option ID = 11218]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
--- Content provided by FirstRanker.com ---
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture[Question ID = 2787]
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
--- Content provided by FirstRanker.com ---
4. activate receptor tyrosine kinase [Option ID = 11146]Correct Answer :-
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
--- Content provided by FirstRanker.com ---
1. serotonin receptors [Option ID = 11283]2. nicotinic receptors [Option ID = 11282]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
--- Content provided by FirstRanker.com ---
GABA alpha receptors [Option ID = 11284]There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
--- Content provided by FirstRanker.com ---
2. Database mining [Option ID = 11190]3. Me too drugs [Option ID = 11192]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
--- Content provided by FirstRanker.com ---
Alpha subunit of heterotrimeric G-protein functions as[Question ID = 2802]
12)
13)
14)
--- Content provided by FirstRanker.com ---
15)16)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
--- Content provided by FirstRanker.com ---
3. cGMP-specific phosphodiesterase [Option ID = 11207]4. GDP kinase [Option ID = 11206]
Correct Answer :-
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
--- Content provided by FirstRanker.com ---
between[Question ID = 2807]
1. 2240 -2360 cm
-1
[Option ID = 11226]
--- Content provided by FirstRanker.com ---
2. 1660 - 1770 cm-1
[Option ID = 11228]
3. 1915-2025 cm
-1
--- Content provided by FirstRanker.com ---
[Option ID = 11227]4. 3400 - 3510 cm
-1
[Option ID = 11225]
Correct Answer :-
--- Content provided by FirstRanker.com ---
1660 - 1770 cm-1
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
--- Content provided by FirstRanker.com ---
2. none of these [Option ID = 11264]3. cyclobutane [Option ID = 11261]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
cyclobutene [Option ID = 11262]
--- Content provided by FirstRanker.com ---
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitatedcomplex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
--- Content provided by FirstRanker.com ---
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]3. All three protein bands are of ?X? protein [Option ID = 11164]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
--- Content provided by FirstRanker.com ---
Under which of the following conditions Lac operon will be functional?[Question ID = 2782]
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
--- Content provided by FirstRanker.com ---
4. only lactose is present [Option ID = 11127]Correct Answer :-
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
--- Content provided by FirstRanker.com ---
2. a protic acid [Option ID = 11275]3. electrophile [Option ID = 11274]
4. a base [Option ID = 11276]
Correct Answer :-
electrophile [Option ID = 11274]
--- Content provided by FirstRanker.com ---
Cisplatin acts as an anti-cancer drug by18)
19)
20)
21)
--- Content provided by FirstRanker.com ---
22)23)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
--- Content provided by FirstRanker.com ---
3. Formation of GG adducts [Option ID = 11267]4. Formation of AA adducts [Option ID = 11268]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
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1. A compound that acts as the starting point for drug design [Option ID = 11183]2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
--- Content provided by FirstRanker.com ---
A compound that acts as the starting point for drug design [Option ID = 11183]Canscora decussata is more commonly known as [Question ID = 2824]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
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4. amla [Option ID = 11293]Correct Answer :-
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
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[Question ID = 2789]1. Arginine [Option ID = 11154]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
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Correct Answer :-Lysine [Option ID = 11153]
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
1. spike potential [Option ID = 11119]
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2. absolute refractory period [Option ID = 11117]3. overshoot [Option ID = 11120]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
relative refractory period [Option ID = 11118]
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Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?[Question ID = 2801]
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
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4. Oct4, Sox2, Nanog [Option ID = 11201]Correct Answer :-
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
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24)25)
26)
27)
28)
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1. 0.13 [Option ID = 11233]2. 0.39 [Option ID = 11235]
3. 0.52 [Option ID = 11236]
4. 0.26 [Option ID = 11234]
Correct Answer :-
--- Content provided by FirstRanker.com ---
0.26 [Option ID = 11234]White matter in brain lacks [Question ID = 2825]
1. Both Axons and Oligodendrocytes [Option ID = 11300]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
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4. Oligodendrocytes [Option ID = 11298]Correct Answer :-
Neuronal cell bodies [Option ID = 11299]
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
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these cells? [Question ID = 2803]1. there will not be any X chromosome inactivation. [Option ID = 11209]
2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
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Correct Answer :-the Xist-deleted chromosome will always be active. [Option ID = 11211]
Difference between systemic and glomerular capillaries is
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
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2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
4. surface area of glomerular capillary is more [Option ID = 11113]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
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A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimentalresults were obtained:
1. Protein moved more slowly on SDS PAGE
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2. Isoelectric Focusing (IEF) showed that there was no change in the PI
3. Mass spectrometric analysis showed that the modification was on serine
--- Content provided by FirstRanker.com ---
The modification that the protein undergoes is likely to be
[Question ID = 2788]
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
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3. Phosphorylation [Option ID = 11149]4. ADP-ribosylation [Option ID = 11152]
Correct Answer :-
Glycosylation [Option ID = 11150]
Esperamicin is an
--- Content provided by FirstRanker.com ---
[Question ID = 2813]1. an anti-tumor antibiotic [Option ID = 11251]
2. anti-hypertensive drug [Option ID = 11249]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
--- Content provided by FirstRanker.com ---
29)30)
31)
32)
33)
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34)Correct Answer :-
an anti-tumor antibiotic [Option ID = 11251]
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
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1. x = 6.00g [Option ID = 11240]2. x = 5.30g [Option ID = 11237]
3. x = 5.50g [Option ID = 11238]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
--- Content provided by FirstRanker.com ---
x = 5.75g [Option ID = 11239]Ashwagandha is a natural product with
[Question ID = 2823]
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
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3. the property of preventing amoebic infections [Option ID = 11291]4. anti-stress and anti-cancer activity [Option ID = 11289]
Correct Answer :-
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
--- Content provided by FirstRanker.com ---
[Question ID = 2786]1. receptor tyrosine kinase [Option ID = 11143]
2. src kinase [Option ID = 11144]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
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Correct Answer :-apoptotic protein [Option ID = 11141]
Radiolabelling of DNA with P
32
radioisotope takes place at
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[Question ID = 2784]1. phosphodiester bonds [Option ID = 11135]
2. none of these [Option ID = 11136]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
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Correct Answer :-5? end of DNA [Option ID = 11133]
Tendency of cells to form colonies is increased by
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
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2. inhibiting intracellular calcium [Option ID = 11131]3. inhibiting extracellular calcium [Option ID = 11129]
4. increasing extracellular calcium [Option ID = 11130]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
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The enzyme lactate dehydrogenase converts [Question ID = 2812]1. lactate to acetaldehyde [Option ID = 11246]
2. pyruvate to lactate [Option ID = 11245]
FirstRanker.com - FirstRanker's Choice
1)
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2)3)
4)
5)
DU PhD In Biomedcal Sciences
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Topic:- DU_J18_PHD_BIOSCI_Topic01What fraction of total blood volume is present in the capillaries at any given time?
[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
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3. 20% [Option ID = 11110]4. 15% [Option ID = 11111]
Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
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[Question ID = 2797]1. The high throughput screening [Option ID = 11186]
2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
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Correct Answer :-The high throughput screening [Option ID = 11186]
What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
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2. The complete three-dimensional conformation [Option ID = 11178]3. Partial denaturation [Option ID = 11179]
4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
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The Michaelis-Menten constant Km is[Question ID = 2826]
1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
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2. Equivalent to the substrate concentration at which V0
is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
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is one fourth Vmax [Option ID = 11304]4. Equivalent to the substrate concentration at which V
0
is one third V max [Option ID = 11302]
Correct Answer :-
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Equivalent to the substrate concentration at which V0
is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
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1. Voltage adjustment [Option ID = 11195]2. Compensation [Option ID = 11194]
3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Compensation [Option ID = 11194]6)
7)
8)
9)
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10)11)
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
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1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =11230]
2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
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Correct Answer :-All of these [Option ID = 11232]
The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
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2. the peptide bond is non-planar [Option ID = 11217]3. each ? and ? pair can assume two different conformation [Option ID = 11218]
4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
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Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture[Question ID = 2787]
1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
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4. activate receptor tyrosine kinase [Option ID = 11146]Correct Answer :-
inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
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1. serotonin receptors [Option ID = 11283]2. nicotinic receptors [Option ID = 11282]
3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
--- Content provided by FirstRanker.com ---
GABA alpha receptors [Option ID = 11284]There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
of a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
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2. Database mining [Option ID = 11190]3. Me too drugs [Option ID = 11192]
4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
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Alpha subunit of heterotrimeric G-protein functions as[Question ID = 2802]
12)
13)
14)
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15)16)
17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
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3. cGMP-specific phosphodiesterase [Option ID = 11207]4. GDP kinase [Option ID = 11206]
Correct Answer :-
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
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between[Question ID = 2807]
1. 2240 -2360 cm
-1
[Option ID = 11226]
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2. 1660 - 1770 cm-1
[Option ID = 11228]
3. 1915-2025 cm
-1
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[Option ID = 11227]4. 3400 - 3510 cm
-1
[Option ID = 11225]
Correct Answer :-
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1660 - 1770 cm-1
[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
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2. none of these [Option ID = 11264]3. cyclobutane [Option ID = 11261]
4. cyclobutene [Option ID = 11262]
Correct Answer :-
cyclobutene [Option ID = 11262]
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Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitatedcomplex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
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2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]3. All three protein bands are of ?X? protein [Option ID = 11164]
4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
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Under which of the following conditions Lac operon will be functional?[Question ID = 2782]
1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
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4. only lactose is present [Option ID = 11127]Correct Answer :-
only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
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2. a protic acid [Option ID = 11275]3. electrophile [Option ID = 11274]
4. a base [Option ID = 11276]
Correct Answer :-
electrophile [Option ID = 11274]
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Cisplatin acts as an anti-cancer drug by18)
19)
20)
21)
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22)23)
[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
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3. Formation of GG adducts [Option ID = 11267]4. Formation of AA adducts [Option ID = 11268]
Correct Answer :-
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
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1. A compound that acts as the starting point for drug design [Option ID = 11183]2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
--- Content provided by FirstRanker.com ---
A compound that acts as the starting point for drug design [Option ID = 11183]Canscora decussata is more commonly known as [Question ID = 2824]
1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
--- Content provided by FirstRanker.com ---
4. amla [Option ID = 11293]Correct Answer :-
shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
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[Question ID = 2789]1. Arginine [Option ID = 11154]
2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
--- Content provided by FirstRanker.com ---
Correct Answer :-Lysine [Option ID = 11153]
A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
1. spike potential [Option ID = 11119]
--- Content provided by FirstRanker.com ---
2. absolute refractory period [Option ID = 11117]3. overshoot [Option ID = 11120]
4. relative refractory period [Option ID = 11118]
Correct Answer :-
relative refractory period [Option ID = 11118]
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Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?[Question ID = 2801]
1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
--- Content provided by FirstRanker.com ---
4. Oct4, Sox2, Nanog [Option ID = 11201]Correct Answer :-
Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
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24)25)
26)
27)
28)
--- Content provided by FirstRanker.com ---
1. 0.13 [Option ID = 11233]2. 0.39 [Option ID = 11235]
3. 0.52 [Option ID = 11236]
4. 0.26 [Option ID = 11234]
Correct Answer :-
--- Content provided by FirstRanker.com ---
0.26 [Option ID = 11234]White matter in brain lacks [Question ID = 2825]
1. Both Axons and Oligodendrocytes [Option ID = 11300]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
--- Content provided by FirstRanker.com ---
4. Oligodendrocytes [Option ID = 11298]Correct Answer :-
Neuronal cell bodies [Option ID = 11299]
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
--- Content provided by FirstRanker.com ---
these cells? [Question ID = 2803]1. there will not be any X chromosome inactivation. [Option ID = 11209]
2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
--- Content provided by FirstRanker.com ---
Correct Answer :-the Xist-deleted chromosome will always be active. [Option ID = 11211]
Difference between systemic and glomerular capillaries is
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
--- Content provided by FirstRanker.com ---
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
4. surface area of glomerular capillary is more [Option ID = 11113]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
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A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimentalresults were obtained:
1. Protein moved more slowly on SDS PAGE
--- Content provided by FirstRanker.com ---
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
3. Mass spectrometric analysis showed that the modification was on serine
--- Content provided by FirstRanker.com ---
The modification that the protein undergoes is likely to be
[Question ID = 2788]
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
--- Content provided by FirstRanker.com ---
3. Phosphorylation [Option ID = 11149]4. ADP-ribosylation [Option ID = 11152]
Correct Answer :-
Glycosylation [Option ID = 11150]
Esperamicin is an
--- Content provided by FirstRanker.com ---
[Question ID = 2813]1. an anti-tumor antibiotic [Option ID = 11251]
2. anti-hypertensive drug [Option ID = 11249]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
--- Content provided by FirstRanker.com ---
29)30)
31)
32)
33)
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34)Correct Answer :-
an anti-tumor antibiotic [Option ID = 11251]
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
--- Content provided by FirstRanker.com ---
1. x = 6.00g [Option ID = 11240]2. x = 5.30g [Option ID = 11237]
3. x = 5.50g [Option ID = 11238]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
--- Content provided by FirstRanker.com ---
x = 5.75g [Option ID = 11239]Ashwagandha is a natural product with
[Question ID = 2823]
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
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3. the property of preventing amoebic infections [Option ID = 11291]4. anti-stress and anti-cancer activity [Option ID = 11289]
Correct Answer :-
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
--- Content provided by FirstRanker.com ---
[Question ID = 2786]1. receptor tyrosine kinase [Option ID = 11143]
2. src kinase [Option ID = 11144]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
--- Content provided by FirstRanker.com ---
Correct Answer :-apoptotic protein [Option ID = 11141]
Radiolabelling of DNA with P
32
radioisotope takes place at
--- Content provided by FirstRanker.com ---
[Question ID = 2784]1. phosphodiester bonds [Option ID = 11135]
2. none of these [Option ID = 11136]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
--- Content provided by FirstRanker.com ---
Correct Answer :-5? end of DNA [Option ID = 11133]
Tendency of cells to form colonies is increased by
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
--- Content provided by FirstRanker.com ---
2. inhibiting intracellular calcium [Option ID = 11131]3. inhibiting extracellular calcium [Option ID = 11129]
4. increasing extracellular calcium [Option ID = 11130]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
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The enzyme lactate dehydrogenase converts [Question ID = 2812]1. lactate to acetaldehyde [Option ID = 11246]
2. pyruvate to lactate [Option ID = 11245]
35)
36)
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37)38)
39)
3. pyruvate to acetaldehyde [Option ID = 11247]
4. acetaldehyde to acetic acid [Option ID = 11248]
--- Content provided by FirstRanker.com ---
Correct Answer :-pyruvate to lactate [Option ID = 11245]
How many pi molecular orbitals are present in hexatriene?
[Question ID = 2815]
1. 5 [Option ID = 11258]
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2. 4 [Option ID = 11257]3. 12 [Option ID = 11260]
4. 6 [Option ID = 11259]
Correct Answer :-
6 [Option ID = 11259]
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How many molecular orbitals are formed by combining 4 atomic orbitals?[Question ID = 2820]
1. 4 [Option ID = 11279]
2. 2 [Option ID = 11277]
3. 3 [Option ID = 11278]
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4. 8 [Option ID = 11280]Correct Answer :-
4 [Option ID = 11279]
To determine the stability of protein ?A? under stimulus of hormone to cells, which of the following experiments should be carried
out?
--- Content provided by FirstRanker.com ---
[Question ID = 2781]1. Cell should be grown in the presence and absence of hormone. After different time intervals, protein is isolated and fractionated on SDS-PAGE and
western blot performed [Option ID = 11122]
2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present
[Option ID = 11124]
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3. Extract total protein from the cell. In one tube add hormone and in another tube add buffer. Carry out western blotting for the protein A, using specificantibodies at different time intervals. [Option ID = 11121]
4. Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc).
Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrsetc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
In an experiment to detect DNA methylation in regulatory region of globin gene, which of the following method is recommended?
[Question ID = 2790]
1. PCR amplification and sequencing [Option ID = 11157]
--- Content provided by FirstRanker.com ---
2. Restriction enzyme digestion and southern hybridization [Option ID = 11160]3. Digestion with methylated sensitive restriction enzyme and electrophoresis [Option ID = 11158]
4. Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
Correct Answer :-
Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
--- Content provided by FirstRanker.com ---
In a population from a recently discovered island in the Indian ocean, most of the people were of blood group O. This indicates that[Question ID = 2804]
1. This a case of pseudo-genes [Option ID = 11215]
2. This is a case of pseudo-dominance [Option ID = 11216]
3. This is due to high rate of mutation [Option ID = 11214]
--- Content provided by FirstRanker.com ---
4. Blood group O is a truly dominant allele [Option ID = 11213]FirstRanker.com - FirstRanker's Choice
1)
2)
3)
--- Content provided by FirstRanker.com ---
4)5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
What fraction of total blood volume is present in the capillaries at any given time?
--- Content provided by FirstRanker.com ---
[Question ID = 2778]1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
4. 15% [Option ID = 11111]
--- Content provided by FirstRanker.com ---
Correct Answer :-5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
1. The high throughput screening [Option ID = 11186]
--- Content provided by FirstRanker.com ---
2. Robotic testing [Option ID = 11185]3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
The high throughput screening [Option ID = 11186]
--- Content provided by FirstRanker.com ---
What does quaternary structure of a protein involve?[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
3. Partial denaturation [Option ID = 11179]
--- Content provided by FirstRanker.com ---
4. Random coil alternating with alpha helix [Option ID = 11180]Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
[Question ID = 2826]
--- Content provided by FirstRanker.com ---
1. Equivalent to the substrate concentration at which V0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is equal to Vmax [Option ID = 11301]3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
4. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
0
--- Content provided by FirstRanker.com ---
is one half of Vmax [Option ID = 11303]The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
2. Compensation [Option ID = 11194]
--- Content provided by FirstRanker.com ---
3. Binary correction [Option ID = 11196]4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
6)
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7)8)
9)
10)
11)
--- Content provided by FirstRanker.com ---
The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nucleardistances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
11230]
--- Content provided by FirstRanker.com ---
2. All of these [Option ID = 11232]3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
All of these [Option ID = 11232]
--- Content provided by FirstRanker.com ---
The Ramachandran plot illustrates the fact that[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
3. each ? and ? pair can assume two different conformation [Option ID = 11218]
--- Content provided by FirstRanker.com ---
4. each ? and ? pair can assume any conformation [Option ID = 11220]Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
[Question ID = 2787]
--- Content provided by FirstRanker.com ---
1. none of these [Option ID = 11148]2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
Correct Answer :-
--- Content provided by FirstRanker.com ---
inhibits receptor tyrosine kinase activation [Option ID = 11145]Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
2. nicotinic receptors [Option ID = 11282]
--- Content provided by FirstRanker.com ---
3. muscarinic receptors [Option ID = 11281]4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery
--- Content provided by FirstRanker.com ---
of a complex structure which is likely to be different from other previously discovered?[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
3. Me too drugs [Option ID = 11192]
--- Content provided by FirstRanker.com ---
4. Combinatorial chemistry [Option ID = 11189]Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
[Question ID = 2802]
--- Content provided by FirstRanker.com ---
12)13)
14)
15)
16)
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17)1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
4. GDP kinase [Option ID = 11206]
--- Content provided by FirstRanker.com ---
Correct Answer :-GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
[Question ID = 2807]
--- Content provided by FirstRanker.com ---
1. 2240 -2360 cm-1
[Option ID = 11226]
2. 1660 - 1770 cm
-1
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[Option ID = 11228]3. 1915-2025 cm
-1
[Option ID = 11227]
4. 3400 - 3510 cm
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-1[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
-1
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[Option ID = 11228]Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
3. cyclobutane [Option ID = 11261]
--- Content provided by FirstRanker.com ---
4. cyclobutene [Option ID = 11262]Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), then
--- Content provided by FirstRanker.com ---
probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [QuestionID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
3. All three protein bands are of ?X? protein [Option ID = 11164]
--- Content provided by FirstRanker.com ---
4. Degradation product of Protein ?X? [Option ID = 11163]Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
[Question ID = 2782]
--- Content provided by FirstRanker.com ---
1. All these condition [Option ID = 11128]2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
Correct Answer :-
--- Content provided by FirstRanker.com ---
only lactose is present [Option ID = 11127]Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
3. electrophile [Option ID = 11274]
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4. a base [Option ID = 11276]Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
18)
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19)20)
21)
22)
23)
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[Question ID = 2817]1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
3. Formation of GG adducts [Option ID = 11267]
4. Formation of AA adducts [Option ID = 11268]
--- Content provided by FirstRanker.com ---
Correct Answer :-Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
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3. A drug containing the element lead [Option ID = 11181]4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
A compound that acts as the starting point for drug design [Option ID = 11183]
Canscora decussata is more commonly known as [Question ID = 2824]
--- Content provided by FirstRanker.com ---
1. shankhpushpi [Option ID = 11295]2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
4. amla [Option ID = 11293]
Correct Answer :-
--- Content provided by FirstRanker.com ---
shankhpushpi [Option ID = 11295]Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
[Question ID = 2789]
1. Arginine [Option ID = 11154]
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2. Asparagine [Option ID = 11155]3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Correct Answer :-
Lysine [Option ID = 11153]
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A stronger than normal stimulus can cause excitation of nerve or muscle during[Question ID = 2780]
1. spike potential [Option ID = 11119]
2. absolute refractory period [Option ID = 11117]
3. overshoot [Option ID = 11120]
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4. relative refractory period [Option ID = 11118]Correct Answer :-
relative refractory period [Option ID = 11118]
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
[Question ID = 2801]
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1. Sox2, CDX2, Nanog [Option ID = 11204]2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
4. Oct4, Sox2, Nanog [Option ID = 11201]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Oct4, Sox2, Nanog [Option ID = 11201]Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
24)
25)
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26)27)
28)
1. 0.13 [Option ID = 11233]
2. 0.39 [Option ID = 11235]
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3. 0.52 [Option ID = 11236]4. 0.26 [Option ID = 11234]
Correct Answer :-
0.26 [Option ID = 11234]
White matter in brain lacks [Question ID = 2825]
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1. Both Axons and Oligodendrocytes [Option ID = 11300]2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
4. Oligodendrocytes [Option ID = 11298]
Correct Answer :-
--- Content provided by FirstRanker.com ---
Neuronal cell bodies [Option ID = 11299]Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
these cells? [Question ID = 2803]
1. there will not be any X chromosome inactivation. [Option ID = 11209]
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2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
Correct Answer :-
the Xist-deleted chromosome will always be active. [Option ID = 11211]
--- Content provided by FirstRanker.com ---
Difference between systemic and glomerular capillaries is[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
3. filtration rate is low in Glomerular capillaries [Option ID = 11115]
--- Content provided by FirstRanker.com ---
4. surface area of glomerular capillary is more [Option ID = 11113]Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental
results were obtained:
--- Content provided by FirstRanker.com ---
1. Protein moved more slowly on SDS PAGE
2. Isoelectric Focusing (IEF) showed that there was no change in the PI
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3. Mass spectrometric analysis showed that the modification was on serine
The modification that the protein undergoes is likely to be
--- Content provided by FirstRanker.com ---
[Question ID = 2788]1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
3. Phosphorylation [Option ID = 11149]
4. ADP-ribosylation [Option ID = 11152]
--- Content provided by FirstRanker.com ---
Correct Answer :-Glycosylation [Option ID = 11150]
Esperamicin is an
[Question ID = 2813]
1. an anti-tumor antibiotic [Option ID = 11251]
--- Content provided by FirstRanker.com ---
2. anti-hypertensive drug [Option ID = 11249]3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
29)
30)
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31)32)
33)
34)
Correct Answer :-
--- Content provided by FirstRanker.com ---
an anti-tumor antibiotic [Option ID = 11251]5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
1. x = 6.00g [Option ID = 11240]
2. x = 5.30g [Option ID = 11237]
--- Content provided by FirstRanker.com ---
3. x = 5.50g [Option ID = 11238]4. x = 5.75g [Option ID = 11239]
Correct Answer :-
x = 5.75g [Option ID = 11239]
Ashwagandha is a natural product with
--- Content provided by FirstRanker.com ---
[Question ID = 2823]1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
3. the property of preventing amoebic infections [Option ID = 11291]
4. anti-stress and anti-cancer activity [Option ID = 11289]
--- Content provided by FirstRanker.com ---
Correct Answer :-anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
[Question ID = 2786]
1. receptor tyrosine kinase [Option ID = 11143]
--- Content provided by FirstRanker.com ---
2. src kinase [Option ID = 11144]3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
Correct Answer :-
apoptotic protein [Option ID = 11141]
--- Content provided by FirstRanker.com ---
Radiolabelling of DNA with P32
radioisotope takes place at
[Question ID = 2784]
1. phosphodiester bonds [Option ID = 11135]
--- Content provided by FirstRanker.com ---
2. none of these [Option ID = 11136]3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
Correct Answer :-
5? end of DNA [Option ID = 11133]
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Tendency of cells to form colonies is increased by[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
2. inhibiting intracellular calcium [Option ID = 11131]
3. inhibiting extracellular calcium [Option ID = 11129]
--- Content provided by FirstRanker.com ---
4. increasing extracellular calcium [Option ID = 11130]Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
The enzyme lactate dehydrogenase converts [Question ID = 2812]
1. lactate to acetaldehyde [Option ID = 11246]
--- Content provided by FirstRanker.com ---
2. pyruvate to lactate [Option ID = 11245]35)
36)
37)
38)
--- Content provided by FirstRanker.com ---
39)3. pyruvate to acetaldehyde [Option ID = 11247]
4. acetaldehyde to acetic acid [Option ID = 11248]
Correct Answer :-
pyruvate to lactate [Option ID = 11245]
--- Content provided by FirstRanker.com ---
How many pi molecular orbitals are present in hexatriene?[Question ID = 2815]
1. 5 [Option ID = 11258]
2. 4 [Option ID = 11257]
3. 12 [Option ID = 11260]
--- Content provided by FirstRanker.com ---
4. 6 [Option ID = 11259]Correct Answer :-
6 [Option ID = 11259]
How many molecular orbitals are formed by combining 4 atomic orbitals?
[Question ID = 2820]
--- Content provided by FirstRanker.com ---
1. 4 [Option ID = 11279]2. 2 [Option ID = 11277]
3. 3 [Option ID = 11278]
4. 8 [Option ID = 11280]
Correct Answer :-
--- Content provided by FirstRanker.com ---
4 [Option ID = 11279]To determine the stability of protein ?A? under stimulus of hormone to cells, which of the following experiments should be carried
out?
[Question ID = 2781]
1. Cell should be grown in the presence and absence of hormone. After different time intervals, protein is isolated and fractionated on SDS-PAGE and
--- Content provided by FirstRanker.com ---
western blot performed [Option ID = 11122]2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present
[Option ID = 11124]
3. Extract total protein from the cell. In one tube add hormone and in another tube add buffer. Carry out western blotting for the protein A, using specific
antibodies at different time intervals. [Option ID = 11121]
--- Content provided by FirstRanker.com ---
4. Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc).Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
Correct Answer :-
Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs
etc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
--- Content provided by FirstRanker.com ---
In an experiment to detect DNA methylation in regulatory region of globin gene, which of the following method is recommended?[Question ID = 2790]
1. PCR amplification and sequencing [Option ID = 11157]
2. Restriction enzyme digestion and southern hybridization [Option ID = 11160]
3. Digestion with methylated sensitive restriction enzyme and electrophoresis [Option ID = 11158]
--- Content provided by FirstRanker.com ---
4. Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]Correct Answer :-
Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
In a population from a recently discovered island in the Indian ocean, most of the people were of blood group O. This indicates that
[Question ID = 2804]
--- Content provided by FirstRanker.com ---
1. This a case of pseudo-genes [Option ID = 11215]2. This is a case of pseudo-dominance [Option ID = 11216]
3. This is due to high rate of mutation [Option ID = 11214]
4. Blood group O is a truly dominant allele [Option ID = 11213]
40)
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41)42)
43)
44)
45)
--- Content provided by FirstRanker.com ---
Correct Answer :-This is a case of pseudo-dominance [Option ID = 11216]
Which phospholipid inhibits the release of Cytochrome c from the mitochondria?
[Question ID = 2785]
1. Cardiolipin [Option ID = 11139]
--- Content provided by FirstRanker.com ---
2. Phosphatidyl serine [Option ID = 11137]3. Phosphatidyl choline [Option ID = 11138]
4. None of these [Option ID = 11140]
Correct Answer :-
Cardiolipin [Option ID = 11139]
--- Content provided by FirstRanker.com ---
Which cytokine is primarily responsible for auto immune response?[Question ID = 2800]
1. IL-1 [Option ID = 11199]
2. IL-17 [Option ID = 11200]
3. IL-10 [Option ID = 11197]
--- Content provided by FirstRanker.com ---
4. IL-5 [Option ID = 11198]Correct Answer :-
IL-17 [Option ID = 11200]
Which of the following is true, if carbonyl (C=O) group of i
th
--- Content provided by FirstRanker.com ---
residue in a polypeptide chain hydrogen bonds with i+n residue, where[Question ID = 2806]
1. n=4 is a ?- helix [Option ID = 11222]
2. n=3 is an alpha helix [Option ID = 11223]
3. n=2, peptide degenerates to a non chiral, 2, 2
--- Content provided by FirstRanker.com ---
7helical ribbon [Option ID = 11221]
4. n=5 is a 3.6
13
helix [Option ID = 11224]
--- Content provided by FirstRanker.com ---
Correct Answer :-n=2, peptide degenerates to a non chiral, 2, 2
7
helical ribbon [Option ID = 11221]
Which of the following is NOT a part of the primary proteins structure?
--- Content provided by FirstRanker.com ---
[Question ID = 2794]1. The disulphide linkages [Option ID = 11174]
2. The amino acid sequences [Option ID = 11173]
3. The conformation of the polypeptide backbone [Option ID = 11176]
4. The planar nature of the amide linkage [Option ID = 11175]
--- Content provided by FirstRanker.com ---
Correct Answer :-The disulphide linkages [Option ID = 11174]
Which of the following metal ions is used for the treatment of arthritis?
[Question ID = 2818]
1. Magnesium [Option ID = 11272]
--- Content provided by FirstRanker.com ---
2. Copper [Option ID = 11270]3. Gold [Option ID = 11271]
4. Silver [Option ID = 11269]
Correct Answer :-
Gold [Option ID = 11271]
--- Content provided by FirstRanker.com ---
Which of the following statements is correct?[Question ID = 2814]
FirstRanker.com - FirstRanker's Choice
1)
2)
--- Content provided by FirstRanker.com ---
3)4)
5)
DU PhD In Biomedcal Sciences
Topic:- DU_J18_PHD_BIOSCI_Topic01
--- Content provided by FirstRanker.com ---
What fraction of total blood volume is present in the capillaries at any given time?[Question ID = 2778]
1. 25% [Option ID = 11112]
2. 5% [Option ID = 11109]
3. 20% [Option ID = 11110]
--- Content provided by FirstRanker.com ---
4. 15% [Option ID = 11111]Correct Answer :-
5% [Option ID = 11109]
What is the term used for the automated in vitro testing of large number of compounds using genetically modified cells?
[Question ID = 2797]
--- Content provided by FirstRanker.com ---
1. The high throughput screening [Option ID = 11186]2. Robotic testing [Option ID = 11185]
3. Nanotechnology [Option ID = 11188]
4. Multi-screening [Option ID = 11187]
Correct Answer :-
--- Content provided by FirstRanker.com ---
The high throughput screening [Option ID = 11186]What does quaternary structure of a protein involve?
[Question ID = 2795]
1. The association of two or more peptide chain [Option ID = 11177]
2. The complete three-dimensional conformation [Option ID = 11178]
--- Content provided by FirstRanker.com ---
3. Partial denaturation [Option ID = 11179]4. Random coil alternating with alpha helix [Option ID = 11180]
Correct Answer :-
The association of two or more peptide chain [Option ID = 11177]
The Michaelis-Menten constant Km is
--- Content provided by FirstRanker.com ---
[Question ID = 2826]1. Equivalent to the substrate concentration at which V
0
is one half of Vmax [Option ID = 11303]
2. Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is equal to Vmax [Option ID = 11301]
3. Equivalent to the substrate concentration at which V
0
is one fourth Vmax [Option ID = 11304]
--- Content provided by FirstRanker.com ---
4. Equivalent to the substrate concentration at which V0
is one third V max [Option ID = 11302]
Correct Answer :-
Equivalent to the substrate concentration at which V
--- Content provided by FirstRanker.com ---
0is one half of Vmax [Option ID = 11303]
The process of correcting bleed over of one flourochrome into the emission spectra of the other flourochrome is called
[Question ID = 2799]
1. Voltage adjustment [Option ID = 11195]
--- Content provided by FirstRanker.com ---
2. Compensation [Option ID = 11194]3. Binary correction [Option ID = 11196]
4. Gating [Option ID = 11193]
Correct Answer :-
Compensation [Option ID = 11194]
--- Content provided by FirstRanker.com ---
6)7)
8)
9)
10)
--- Content provided by FirstRanker.com ---
11)The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear
distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?
[Question ID = 2808]
1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID =
--- Content provided by FirstRanker.com ---
11230]2. All of these [Option ID = 11232]
3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
Correct Answer :-
--- Content provided by FirstRanker.com ---
All of these [Option ID = 11232]The Ramachandran plot illustrates the fact that
[Question ID = 2805]
1. the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
2. the peptide bond is non-planar [Option ID = 11217]
--- Content provided by FirstRanker.com ---
3. each ? and ? pair can assume two different conformation [Option ID = 11218]4. each ? and ? pair can assume any conformation [Option ID = 11220]
Correct Answer :-
the conformation in which both ? and ? are 0 is prohibited [Option ID = 11219]
Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture
--- Content provided by FirstRanker.com ---
[Question ID = 2787]1. none of these [Option ID = 11148]
2. initiate receptor dimerization [Option ID = 11147]
3. inhibits receptor tyrosine kinase activation [Option ID = 11145]
4. activate receptor tyrosine kinase [Option ID = 11146]
--- Content provided by FirstRanker.com ---
Correct Answer :-inhibits receptor tyrosine kinase activation [Option ID = 11145]
Benzodiazepine receptors are also known as
[Question ID = 2821]
1. serotonin receptors [Option ID = 11283]
--- Content provided by FirstRanker.com ---
2. nicotinic receptors [Option ID = 11282]3. muscarinic receptors [Option ID = 11281]
4. GABA alpha receptors [Option ID = 11284]
Correct Answer :-
GABA alpha receptors [Option ID = 11284]
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There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discoveryof a complex structure which is likely to be different from other previously discovered?
[Question ID = 2798]
1. Screening plant extract [Option ID = 11191]
2. Database mining [Option ID = 11190]
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3. Me too drugs [Option ID = 11192]4. Combinatorial chemistry [Option ID = 11189]
Correct Answer :-
Screening plant extract [Option ID = 11191]
Alpha subunit of heterotrimeric G-protein functions as
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[Question ID = 2802]12)
13)
14)
15)
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16)17)
1. cAMP-specific phosphodiesterase [Option ID = 11208]
2. GTPase [Option ID = 11205]
3. cGMP-specific phosphodiesterase [Option ID = 11207]
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4. GDP kinase [Option ID = 11206]Correct Answer :-
GTPase [Option ID = 11205]
Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak
between
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[Question ID = 2807]1. 2240 -2360 cm
-1
[Option ID = 11226]
2. 1660 - 1770 cm
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-1[Option ID = 11228]
3. 1915-2025 cm
-1
[Option ID = 11227]
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4. 3400 - 3510 cm-1
[Option ID = 11225]
Correct Answer :-
1660 - 1770 cm
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-1[Option ID = 11228]
Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]
1. methyl cyclopropane [Option ID = 11263]
2. none of these [Option ID = 11264]
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3. cyclobutane [Option ID = 11261]4. cyclobutene [Option ID = 11262]
Correct Answer :-
cyclobutene [Option ID = 11262]
Protein lysates were immunoprecipitated with antibody against human ?X?. Which was raised in mouse. Immunoprecipitated
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complex was subjected to SDS-PAGE, following with western blotting with antibodies to human ?X? antibody (raised in mouse), thenprobed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question
ID = 2791]
1. One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
2. One band is ?X? protein, other two bands are non specific [Option ID = 11161]
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3. All three protein bands are of ?X? protein [Option ID = 11164]4. Degradation product of Protein ?X? [Option ID = 11163]
Correct Answer :-
One band is ?X? protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
Under which of the following conditions Lac operon will be functional?
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[Question ID = 2782]1. All these condition [Option ID = 11128]
2. When lactose and glucose both are present in the media [Option ID = 11126]
3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
4. only lactose is present [Option ID = 11127]
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Correct Answer :-only lactose is present [Option ID = 11127]
Sulphur trioxide is a [Question ID = 2819]
1. nucleophile [Option ID = 11273]
2. a protic acid [Option ID = 11275]
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3. electrophile [Option ID = 11274]4. a base [Option ID = 11276]
Correct Answer :-
electrophile [Option ID = 11274]
Cisplatin acts as an anti-cancer drug by
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18)19)
20)
21)
22)
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23)[Question ID = 2817]
1. DNA Cleavage [Option ID = 11265]
2. Formation of hydroxyl radicals [Option ID = 11266]
3. Formation of GG adducts [Option ID = 11267]
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4. Formation of AA adducts [Option ID = 11268]Correct Answer :-
Formation of GG adducts [Option ID = 11267]
What you mean by a lead compound in drug discovery? [Question ID = 2796]
1. A compound that acts as the starting point for drug design [Option ID = 11183]
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2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]3. A drug containing the element lead [Option ID = 11181]
4. A leading drug in a particular area of medicine [Option ID = 11182]
Correct Answer :-
A compound that acts as the starting point for drug design [Option ID = 11183]
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Canscora decussata is more commonly known as [Question ID = 2824]1. shankhpushpi [Option ID = 11295]
2. hibiscus [Option ID = 11294]
3. bel [Option ID = 11296]
4. amla [Option ID = 11293]
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Correct Answer :-shankhpushpi [Option ID = 11295]
Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is
involved in acetylation?
[Question ID = 2789]
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1. Arginine [Option ID = 11154]2. Asparagine [Option ID = 11155]
3. Histidine [Option ID = 11156]
4. Lysine [Option ID = 11153]
Correct Answer :-
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Lysine [Option ID = 11153]A stronger than normal stimulus can cause excitation of nerve or muscle during
[Question ID = 2780]
1. spike potential [Option ID = 11119]
2. absolute refractory period [Option ID = 11117]
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3. overshoot [Option ID = 11120]4. relative refractory period [Option ID = 11118]
Correct Answer :-
relative refractory period [Option ID = 11118]
Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?
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[Question ID = 2801]1. Sox2, CDX2, Nanog [Option ID = 11204]
2. Oct4, CDX2, Nanog [Option ID = 11203]
3. Oct4, Sox2, CDX2 [Option ID = 11202]
4. Oct4, Sox2, Nanog [Option ID = 11201]
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Correct Answer :-Oct4, Sox2, Nanog [Option ID = 11201]
Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of Tl-
208 will remain unchanged after 9.3 minutes? [Question ID = 2809]
24)
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25)26)
27)
28)
1. 0.13 [Option ID = 11233]
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2. 0.39 [Option ID = 11235]3. 0.52 [Option ID = 11236]
4. 0.26 [Option ID = 11234]
Correct Answer :-
0.26 [Option ID = 11234]
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White matter in brain lacks [Question ID = 2825]1. Both Axons and Oligodendrocytes [Option ID = 11300]
2. Axons [Option ID = 11297]
3. Neuronal cell bodies [Option ID = 11299]
4. Oligodendrocytes [Option ID = 11298]
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Correct Answer :-Neuronal cell bodies [Option ID = 11299]
Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage
compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in
these cells? [Question ID = 2803]
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1. there will not be any X chromosome inactivation. [Option ID = 11209]2. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
3. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
4. the Xist-deleted chromosome will always be active. [Option ID = 11211]
Correct Answer :-
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the Xist-deleted chromosome will always be active. [Option ID = 11211]Difference between systemic and glomerular capillaries is
[Question ID = 2779]
1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
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3. filtration rate is low in Glomerular capillaries [Option ID = 11115]4. surface area of glomerular capillary is more [Option ID = 11113]
Correct Answer :-
blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental
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results were obtained:1. Protein moved more slowly on SDS PAGE
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2. Isoelectric Focusing (IEF) showed that there was no change in the PI3. Mass spectrometric analysis showed that the modification was on serine
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The modification that the protein undergoes is likely to be[Question ID = 2788]
1. Ubiquitination [Option ID = 11151]
2. Glycosylation [Option ID = 11150]
3. Phosphorylation [Option ID = 11149]
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4. ADP-ribosylation [Option ID = 11152]Correct Answer :-
Glycosylation [Option ID = 11150]
Esperamicin is an
[Question ID = 2813]
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1. an anti-tumor antibiotic [Option ID = 11251]2. anti-hypertensive drug [Option ID = 11249]
3. anti-hypercholesterolemic drug [Option ID = 11250]
4. anti- HIV drug [Option ID = 11252]
29)
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30)31)
32)
33)
34)
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Correct Answer :-an anti-tumor antibiotic [Option ID = 11251]
5g of benzaldehyde will yield x g of benzoic acid upon oxidation
[Question ID = 2810]
1. x = 6.00g [Option ID = 11240]
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2. x = 5.30g [Option ID = 11237]3. x = 5.50g [Option ID = 11238]
4. x = 5.75g [Option ID = 11239]
Correct Answer :-
x = 5.75g [Option ID = 11239]
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Ashwagandha is a natural product with[Question ID = 2823]
1. none of these [Option ID = 11292]
2. the property of preventing gastric ulcers [Option ID = 11290]
3. the property of preventing amoebic infections [Option ID = 11291]
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4. anti-stress and anti-cancer activity [Option ID = 11289]Correct Answer :-
anti-stress and anti-cancer activity [Option ID = 11289]
BH3 domain containing protein is
[Question ID = 2786]
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1. receptor tyrosine kinase [Option ID = 11143]2. src kinase [Option ID = 11144]
3. apoptotic protein [Option ID = 11141]
4. anti-apoptotic protein [Option ID = 11142]
Correct Answer :-
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apoptotic protein [Option ID = 11141]Radiolabelling of DNA with P
32
radioisotope takes place at
[Question ID = 2784]
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1. phosphodiester bonds [Option ID = 11135]2. none of these [Option ID = 11136]
3. 3? end of DNA [Option ID = 11134]
4. 5? end of DNA [Option ID = 11133]
Correct Answer :-
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5? end of DNA [Option ID = 11133]Tendency of cells to form colonies is increased by
[Question ID = 2783]
1. incubation with calcium chelators [Option ID = 11132]
2. inhibiting intracellular calcium [Option ID = 11131]
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3. inhibiting extracellular calcium [Option ID = 11129]4. increasing extracellular calcium [Option ID = 11130]
Correct Answer :-
increasing extracellular calcium [Option ID = 11130]
The enzyme lactate dehydrogenase converts [Question ID = 2812]
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1. lactate to acetaldehyde [Option ID = 11246]2. pyruvate to lactate [Option ID = 11245]
35)
36)
37)
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38)39)
3. pyruvate to acetaldehyde [Option ID = 11247]
4. acetaldehyde to acetic acid [Option ID = 11248]
Correct Answer :-
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pyruvate to lactate [Option ID = 11245]How many pi molecular orbitals are present in hexatriene?
[Question ID = 2815]
1. 5 [Option ID = 11258]
2. 4 [Option ID = 11257]
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3. 12 [Option ID = 11260]4. 6 [Option ID = 11259]
Correct Answer :-
6 [Option ID = 11259]
How many molecular orbitals are formed by combining 4 atomic orbitals?
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[Question ID = 2820]1. 4 [Option ID = 11279]
2. 2 [Option ID = 11277]
3. 3 [Option ID = 11278]
4. 8 [Option ID = 11280]
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Correct Answer :-4 [Option ID = 11279]
To determine the stability of protein ?A? under stimulus of hormone to cells, which of the following experiments should be carried
out?
[Question ID = 2781]
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1. Cell should be grown in the presence and absence of hormone. After different time intervals, protein is isolated and fractionated on SDS-PAGE andwestern blot performed [Option ID = 11122]
2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present
[Option ID = 11124]
3. Extract total protein from the cell. In one tube add hormone and in another tube add buffer. Carry out western blotting for the protein A, using specific
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antibodies at different time intervals. [Option ID = 11121]4. Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc).
Isolate the total protein and do western blot for the protein A. [Option ID = 11123]
Correct Answer :-
Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs
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etc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]In an experiment to detect DNA methylation in regulatory region of globin gene, which of the following method is recommended?
[Question ID = 2790]
1. PCR amplification and sequencing [Option ID = 11157]
2. Restriction enzyme digestion and southern hybridization [Option ID = 11160]
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3. Digestion with methylated sensitive restriction enzyme and electrophoresis [Option ID = 11158]4. Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
Correct Answer :-
Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]
In a population from a recently discovered island in the Indian ocean, most of the people were of blood group O. This indicates that
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[Question ID = 2804]1. This a case of pseudo-genes [Option ID = 11215]
2. This is a case of pseudo-dominance [Option ID = 11216]
3. This is due to high rate of mutation [Option ID = 11214]
4. Blood group O is a truly dominant allele [Option ID = 11213]
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40)41)
42)
43)
44)
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45)Correct Answer :-
This is a case of pseudo-dominance [Option ID = 11216]
Which phospholipid inhibits the release of Cytochrome c from the mitochondria?
[Question ID = 2785]
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1. Cardiolipin [Option ID = 11139]2. Phosphatidyl serine [Option ID = 11137]
3. Phosphatidyl choline [Option ID = 11138]
4. None of these [Option ID = 11140]
Correct Answer :-
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Cardiolipin [Option ID = 11139]Which cytokine is primarily responsible for auto immune response?
[Question ID = 2800]
1. IL-1 [Option ID = 11199]
2. IL-17 [Option ID = 11200]
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3. IL-10 [Option ID = 11197]4. IL-5 [Option ID = 11198]
Correct Answer :-
IL-17 [Option ID = 11200]
Which of the following is true, if carbonyl (C=O) group of i
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thresidue in a polypeptide chain hydrogen bonds with i+n residue, where
[Question ID = 2806]
1. n=4 is a ?- helix [Option ID = 11222]
2. n=3 is an alpha helix [Option ID = 11223]
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3. n=2, peptide degenerates to a non chiral, 2, 27
helical ribbon [Option ID = 11221]
4. n=5 is a 3.6
13
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helix [Option ID = 11224]Correct Answer :-
n=2, peptide degenerates to a non chiral, 2, 2
7
helical ribbon [Option ID = 11221]
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Which of the following is NOT a part of the primary proteins structure?[Question ID = 2794]
1. The disulphide linkages [Option ID = 11174]
2. The amino acid sequences [Option ID = 11173]
3. The conformation of the polypeptide backbone [Option ID = 11176]
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4. The planar nature of the amide linkage [Option ID = 11175]Correct Answer :-
The disulphide linkages [Option ID = 11174]
Which of the following metal ions is used for the treatment of arthritis?
[Question ID = 2818]
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1. Magnesium [Option ID = 11272]2. Copper [Option ID = 11270]
3. Gold [Option ID = 11271]
4. Silver [Option ID = 11269]
Correct Answer :-
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Gold [Option ID = 11271]Which of the following statements is correct?
[Question ID = 2814]
46)
47)
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48)49)
50)
1. DNA polymerase is DNA alkylator [Option ID = 11256]
2. Netropsin is a major groove binder [Option ID = 11255]
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3. Ethidium bromide is a minor groove binder [Option ID = 11253]4. Ethidium bromide intercalates with DNA [Option ID = 11254]
Correct Answer :-
Ethidium bromide intercalates with DNA [Option ID = 11254]
Which of the following statements is false about the NMR experiment?
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[Question ID = 2792]1. The energy required to flip the spin of a system is in the infrared region of the electromagnetic spectrum [Option ID = 11165]
2. The energy difference between two spin states depends on the strength of the magnetic field [Option ID = 11166]
3. When energy absorption occurs, the nuclei are said to be in resonance with the electromagnetic radiation [Option ID = 11167]
4. When a proton is aligned with the magnetic field, its energy is lower than when its is aligned against the magnetic field [Option ID = 11168]
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Correct Answer :-The energy required to flip the spin of a system is in the infrared region of the electromagnetic spectrum [Option ID = 11165]
Which of the following compounds has the most de-shielded proton?
[Question ID = 2793]
1. CH
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3I [Option ID = 11170]
2. CH
3
F [Option ID = 11172]
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3. CH3
Cl [Option ID = 11169]
4. CH
3
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Br [Option ID = 11171]Correct Answer :-
CH
3
F [Option ID = 11172]
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Which of the following symmetry element is present in chloroform?[Question ID = 2822]
1. C
2
axis of symmetry [Option ID = 11286]
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2. C3
axis of symmetry [Option ID = 11285]
3. S
2
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axis of symmetry [Option ID = 11287]4. Center of symmetry [Option ID = 11288]
Correct Answer :-
C
3
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axis of symmetry [Option ID = 11285]Which of these can not pass through the glomerular capillaries under normal condition?
[Question ID = 2777]
1. Albumin [Option ID = 11108]
2. Water [Option ID = 11105]
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3. Sodium [Option ID = 11106]4. Potassium [Option ID = 11107]
Correct Answer :-
Albumin [Option ID = 11108]
Benzotriazole contains [Question ID = 2811]
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1. two nitrogen and one oxygen atom [Option ID = 11241]2. three nitrogen atoms [Option ID = 11243]
3. three nitro groups [Option ID = 11244]
4. two oxygen and one nitrogen atom [Option ID = 11242]
Correct Answer :-
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three nitrogen atoms [Option ID = 11243]FirstRanker.com - FirstRanker's Choice