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Download DUET Master 2018 DU PhD In Biomedcal Sciences Question Paper With Answer Key

Download DUET (Delhi University Entrance Test conducted by the NTA) 2018 DU PhD In Biomedcal Sciences Question Paper With Solution Key

This post was last modified on 29 January 2020

DUET Last 10 Years 2011-2021 Question Papers With Answer Key || Delhi University Entrance Test conducted by the NTA


Topic:- DU_J18_PHD_BIOSCI_Topic01

DU PhD In Biomedical Sciences

  1. 1) What fraction of total blood volume is present in the capillaries at any given time?

    --- Content provided by‍ FirstRanker.com ---

    [Question ID = 2778]

    1. 25% [Option ID = 11112]
    2. 5% [Option ID = 11109]
    3. 20% [Option ID = 11110]
    4. 15% [Option ID = 11111]
    5. --- Content provided by​ FirstRanker.com ---

    Correct Answer :-

    5% [Option ID = 11109]

  2. 2) What is the term used for the automated in vitro testing of a large number of compounds using genetically modified cells?

    [Question ID = 2797]

    --- Content provided by FirstRanker.com ---

    1. The high throughput screening [Option ID = 11186]
    2. Robotic testing [Option ID = 11185]
    3. Nanotechnology [Option ID = 11188]
    4. Multi-screening [Option ID = 11187]

    Correct Answer :-

    --- Content provided by FirstRanker.com ---

    The high throughput screening [Option ID = 11186]

  3. 3) What does quaternary structure of a protein involve?

    [Question ID = 2795]

    1. The association of two or more peptide chains [Option ID = 11177]
    2. --- Content provided by FirstRanker.com ---

    3. The complete three-dimensional conformation [Option ID = 11178]
    4. Partial denaturation [Option ID = 11179]
    5. Random coil alternating with alpha helix [Option ID = 11180]

    Correct Answer :-

    The association of two or more peptide chains [Option ID = 11177]

    --- Content provided by‍ FirstRanker.com ---

  4. 4) The Michaelis-Menten constant Km is

    [Question ID = 2826]

    1. Equivalent to the substrate concentration at which Vo is one half of Vmax [Option ID = 11303]
    2. Equivalent to the substrate concentration at which Vo is equal to Vmax [Option ID = 11301]
    3. --- Content provided by⁠ FirstRanker.com ---

    4. Equivalent to the substrate concentration at which Vo is one fourth Vmax [Option ID = 11304]
    5. Equivalent to the substrate concentration at which Vo is one third V max [Option ID = 11302]

    Correct Answer :-

    Equivalent to the substrate concentration at which Vo is one half of Vmax [Option ID = 11303]

  5. --- Content provided by⁠ FirstRanker.com ---

  6. 5) The process of correcting bleed over of one fluorochrome into the emission spectra of the other fluorochrome is called

    [Question ID = 2799]

    1. Voltage adjustment [Option ID = 11195]
    2. Compensation [Option ID = 11194]
    3. Binary correction [Option ID = 11196]
    4. --- Content provided by​ FirstRanker.com ---

    5. Gating [Option ID = 11193]

    Correct Answer :-

    Compensation [Option ID = 11194]

  7. 6) The time-scale for an electronic transition is much shorter than for vibrational transitions, it can be assumed that inter-nuclear distances will not change during the transition. Which of the statement/s correctly represent the Fluorescence phenomena?

    --- Content provided by⁠ FirstRanker.com ---

    [Question ID = 2808]

    1. Measurement of the fluorescence from a large number of molecules, following a short pulse excitation, will show an exponential decay [Option ID = 11230]
    2. All of these [Option ID = 11232]
    3. Fluorescence lifetime is the average time that an electron spends in the excited state before a photon is emitted [Option ID = 11229]
    4. Fluorescence lifetime is given by the 1/e point of the decay [Option ID = 11231]
    5. --- Content provided by⁠ FirstRanker.com ---

    Correct Answer :-

    All of these [Option ID = 11232]

  8. 7) The Ramachandran plot illustrates the fact that

    [Question ID = 2805]

    --- Content provided by FirstRanker.com ---

    1. the conformation in which both f and ? are 0 is prohibited [Option ID = 11219]
    2. the peptide bond is non-planar [Option ID = 11217]
    3. each f and ? pair can assume two different conformations [Option ID = 11218]
    4. each f and ? pair can assume any conformation [Option ID = 11220]

    Correct Answer :-

    --- Content provided by FirstRanker.com ---

    the conformation in which both f and ? are 0 is prohibited [Option ID = 11219]

  9. 8) Incubating antibodies against the ligand of receptor tyrosine kinase in live cell culture

    [Question ID = 2787]

    1. none of these [Option ID = 11148]
    2. --- Content provided by⁠ FirstRanker.com ---

    3. initiate receptor dimerization [Option ID = 11147]
    4. inhibits receptor tyrosine kinase activation [Option ID = 11145]
    5. activate receptor tyrosine kinase [Option ID = 11146]

    Correct Answer :-

    inhibits receptor tyrosine kinase activation [Option ID = 11145]

    --- Content provided by‌ FirstRanker.com ---

  10. 9) Benzodiazepine receptors are also known as

    [Question ID = 2821]

    1. serotonin receptors [Option ID = 11283]
    2. nicotinic receptors [Option ID = 11282]
    3. --- Content provided by​ FirstRanker.com ---

    4. muscarinic receptors [Option ID = 11281]
    5. GABA alpha receptors [Option ID = 11284]

    Correct Answer :-

    GABA alpha receptors [Option ID = 11284]

  11. --- Content provided by​ FirstRanker.com ---

  12. 10) There are several sources and methods for discovering new compounds, which of the following is most likely to lead to the discovery of a complex structure which is likely to be different from other previously discovered?

    [Question ID = 2798]

    1. Screening plant extract [Option ID = 11191]
    2. Database mining [Option ID = 11190]
    3. Me too drugs [Option ID = 11192]
    4. --- Content provided by FirstRanker.com ---

    5. Combinatorial chemistry [Option ID = 11189]

    Correct Answer :-

    Screening plant extract [Option ID = 11191]

  13. 11) Alpha subunit of heterotrimeric G-protein functions as

    --- Content provided by FirstRanker.com ---

    [Question ID = 2802]

    1. cAMP-specific phosphodiesterase [Option ID = 11208]
    2. GTPase [Option ID = 11205]
    3. cGMP-specific phosphodiesterase [Option ID = 11207]
    4. GDP kinase [Option ID = 11206]
    5. --- Content provided by​ FirstRanker.com ---

    Correct Answer :-

    GTPase [Option ID = 11205]

  14. 12) Infrared spectroscopy is one of the best diagnostic tools for analysis of carbonyl groups having a strong C=O absorption peak between

    [Question ID = 2807]

    --- Content provided by‍ FirstRanker.com ---

    1. 2240 -2360 cm?¹ [Option ID = 11226]
    2. 1660 - 1770 cm?¹ [Option ID = 11228]
    3. 1915-2025 cm?¹ [Option ID = 11227]
    4. 3400 - 3510 cm?¹ [Option ID = 11225]

    Correct Answer :-

    --- Content provided by‌ FirstRanker.com ---

    1660-1770 cm?¹ [Option ID = 11228]

  15. 13) Butadiene changes to the one of the following molecules in the presence of heat [Question ID = 2816]

    1. methyl cyclopropane [Option ID = 11263]
    2. none of these [Option ID = 11264]
    3. --- Content provided by FirstRanker.com ---

    4. cyclobutane [Option ID = 11261]
    5. cyclobutene [Option ID = 11262]

    Correct Answer :-

    cyclobutene [Option ID = 11262]

  16. --- Content provided by⁠ FirstRanker.com ---

  17. 14) Protein lysates were immunoprecipitated with antibody against human "X", which was raised in mouse. Immunoprecipitated complex was subjected to SDS-PAGE, following with western blotting with antibodies to human "X" antibody (raised in mouse), then probed with HRP conjugated secondary antibody to mouse, results in appearance of three distinct protein bands. This indicates [Question ID = 2791]

    1. One band is "X" protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]
    2. One band is "X" protein, other two bands are non-specific [Option ID = 11161]
    3. All three protein bands are of "X" protein [Option ID = 11164]
    4. Degradation product of Protein "X" [Option ID = 11163]
    5. --- Content provided by⁠ FirstRanker.com ---

    Correct Answer :-

    One band is "X" protein and other two protein bands are IgG H chain, and IgG L chain [Option ID = 11162]

  18. 15) Under which of the following conditions Lac operon will be functional?

    [Question ID = 2782]

    --- Content provided by​ FirstRanker.com ---

    1. All these conditions [Option ID = 11128]
    2. When lactose and glucose both are present in the media [Option ID = 11126]
    3. When glucose + lactose + galactose are provided in the medium together [Option ID = 11125]
    4. only lactose is present [Option ID = 11127]

    Correct Answer :-

    --- Content provided by⁠ FirstRanker.com ---

    only lactose is present [Option ID = 11127]

  19. 16) Sulphur trioxide is a [Question ID = 2819]

    1. nucleophile [Option ID = 11273]
    2. a protic acid [Option ID = 11275]
    3. --- Content provided by‌ FirstRanker.com ---

    4. electrophile [Option ID = 11274]
    5. a base [Option ID = 11276]

    Correct Answer :-

    electrophile [Option ID = 11274]

  20. --- Content provided by​ FirstRanker.com ---

  21. 17) Cisplatin acts as an anti-cancer drug by

    [Question ID = 2817]

    1. DNA Cleavage [Option ID = 11265]
    2. Formation of hydroxyl radicals [Option ID = 11266]
    3. Formation of GG adducts [Option ID = 11267]
    4. --- Content provided by⁠ FirstRanker.com ---

    5. Formation of AA adducts [Option ID = 11268]

    Correct Answer :-

    Formation of GG adducts [Option ID = 11267]

  22. 18) What you mean by a lead compound in drug discovery? [Question ID = 2796]

    --- Content provided by‌ FirstRanker.com ---

    1. A compound that acts as the starting point for drug design [Option ID = 11183]
    2. A drug which is normally the first to be prescribed for a particular ailment [Option ID = 11184]
    3. A drug containing the element lead [Option ID = 11181]
    4. A leading drug in a particular area of medicine [Option ID = 11182]

    Correct Answer :-

    --- Content provided by​ FirstRanker.com ---

    A compound that acts as the starting point for drug design [Option ID = 11183]

  23. 19) Canscora decussata is more commonly known as [Question ID = 2824]

    1. shankhpushpi [Option ID = 11295]
    2. hibiscus [Option ID = 11294]
    3. --- Content provided by⁠ FirstRanker.com ---

    4. bel [Option ID = 11296]
    5. amla [Option ID = 11293]

    Correct Answer :-

    shankhpushpi [Option ID = 11295]

  24. --- Content provided by FirstRanker.com ---

  25. 20) Histone deacetylase (HDAC) catalysis the removal of acetyl group from N-terminal of histones. Which amino acid of histone is involved in acetylation?

    [Question ID = 2789]

    1. Arginine [Option ID = 11154]
    2. Asparagine [Option ID = 11155]
    3. Histidine [Option ID = 11156]
    4. --- Content provided by​ FirstRanker.com ---

    5. Lysine [Option ID = 11153]

    Correct Answer :-

    Lysine [Option ID = 11153]

  26. 21) A stronger than normal stimulus can cause excitation of nerve or muscle during

    --- Content provided by‍ FirstRanker.com ---

    [Question ID = 2780]

    1. spike potential [Option ID = 11119]
    2. absolute refractory period [Option ID = 11117]
    3. overshoot [Option ID = 11120]
    4. relative refractory period [Option ID = 11118]
    5. --- Content provided by‍ FirstRanker.com ---

    Correct Answer :-

    relative refractory period [Option ID = 11118]

  27. 22) Pluripotency in the cell is maintained by three transcription factors. Which one of the following is correct?

    [Question ID = 2801]

    --- Content provided by⁠ FirstRanker.com ---

    1. Sox2, CDX2, Nanog [Option ID = 11204]
    2. Oct4, CDX2, Nanog [Option ID = 11203]
    3. Oct4, Sox2, CDX2 [Option ID = 11202]
    4. Oct4, Sox2, Nanog [Option ID = 11201]

    Correct Answer :-

    --- Content provided by‍ FirstRanker.com ---

    Oct4, Sox2, Nanog [Option ID = 11201]

  28. 23) Thallium-208 has a half life of 3.1 minutes and decays by beta emission to form a stable isotope. What mass of a 2.08 g sample of TI- 208 will remain unchanged after 9.3 minutes? [Question ID = 2809]

    1. 0.13 [Option ID = 11233]
    2. 0.39 [Option ID = 11235]
    3. --- Content provided by‍ FirstRanker.com ---

    4. 0.52 [Option ID = 11236]
    5. 0.26 [Option ID = 11234]

    Correct Answer :-

    0.26 [Option ID = 11234]

  29. --- Content provided by FirstRanker.com ---

  30. 24) White matter in brain lacks [Question ID = 2825]

    1. Both Axons and Oligodendrocytes [Option ID = 11300]
    2. Axons [Option ID = 11297]
    3. Neuronal cell bodies [Option ID = 11299]
    4. Oligodendrocytes [Option ID = 11298]
    5. --- Content provided by‍ FirstRanker.com ---

    Correct Answer :-

    Neuronal cell bodies [Option ID = 11299]

  31. 25) Xist is a non-coding RNA mapping on the X chromosome in the mouse, and is necessary for X chromosome inactivation and dosage compensation. An XX cell, has a deletion of the Xist locus in one of the X chromosomes. What is the pattern of X-inactivation you expect in these cells? [Question ID = 2803]

    1. there will not be any X chromosome inactivation. [Option ID = 11209]
    2. --- Content provided by‍ FirstRanker.com ---

    3. it will be random, either the deleted or the normal X chromosome will be inactivated. [Option ID = 11212]
    4. the Xist-deleted chromosome will always be inactivated. [Option ID = 11210]
    5. the Xist-deleted chromosome will always be active. [Option ID = 11211]

    Correct Answer :-

    the Xist-deleted chromosome will always be active. [Option ID = 11211]

    --- Content provided by​ FirstRanker.com ---

  32. 26) Difference between systemic and glomerular capillaries is

    [Question ID = 2779]

    1. blood pressure in systemic capillary is higher than glomerular [Option ID = 11114]
    2. blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]
    3. --- Content provided by‍ FirstRanker.com ---

    4. filtration rate is low in Glomerular capillaries [Option ID = 11115]
    5. surface area of glomerular capillary is more [Option ID = 11113]

    Correct Answer :-

    blood pressure in Glomerular capillaries is higher than systemic capillary [Option ID = 11116]

  33. --- Content provided by​ FirstRanker.com ---

  34. 27) A protein undergoes posttranslational modification. In an experiment to identify the nature of modification, following experimental results were obtained:

    1. Protein moved more slowly on SDS PAGE
    2. Isoelectric Focusing (IEF) showed that there was no change in the PI
    3. Mass spectrometric analysis showed that the modification was on serine

    The modification that the protein undergoes is likely to be

    --- Content provided by‌ FirstRanker.com ---

    [Question ID = 2788]

    1. Ubiquitination [Option ID = 11151]
    2. Glycosylation [Option ID = 11150]
    3. Phosphorylation [Option ID = 11149]
    4. ADP-ribosylation [Option ID = 11152]
    5. --- Content provided by‌ FirstRanker.com ---

    Correct Answer :-

    Glycosylation [Option ID = 11150]

  35. 28) Esperamicin is an

    [Question ID = 2813]

    --- Content provided by‌ FirstRanker.com ---

    1. an anti-tumor antibiotic [Option ID = 11251]
    2. anti-hypertensive drug [Option ID = 11249]
    3. anti-hypercholesterolemic drug [Option ID = 11250]
    4. anti- HIV drug [Option ID = 11252]

    Correct Answer :-

    --- Content provided by FirstRanker.com ---

    an anti-tumor antibiotic [Option ID = 11251]

  36. 29) 5g of benzaldehyde will yield x g of benzoic acid upon oxidation

    [Question ID = 2810]

    1. x = 6.00g [Option ID = 11240]
    2. --- Content provided by​ FirstRanker.com ---

    3. x = 5.30g [Option ID = 11237]
    4. x = 5.50g [Option ID = 11238]
    5. x = 5.75g [Option ID = 11239]

    Correct Answer :-

    x = 5.75g [Option ID = 11239]

    --- Content provided by‌ FirstRanker.com ---

  37. 30) Ashwagandha is a natural product with

    [Question ID = 2823]

    1. none of these [Option ID = 11292]
    2. the property of preventing gastric ulcers [Option ID = 11290]
    3. --- Content provided by⁠ FirstRanker.com ---

    4. the property of preventing amoebic infections [Option ID = 11291]
    5. anti-stress and anti-cancer activity [Option ID = 11289]

    Correct Answer :-

    anti-stress and anti-cancer activity [Option ID = 11289]

  38. --- Content provided by⁠ FirstRanker.com ---

  39. 31) BH3 domain containing protein is

    [Question ID = 2786]

    1. receptor tyrosine kinase [Option ID = 11143]
    2. src kinase [Option ID = 11144]
    3. apoptotic protein [Option ID = 11141]
    4. --- Content provided by‍ FirstRanker.com ---

    5. anti-apoptotic protein [Option ID = 11142]

    Correct Answer :-

    apoptotic protein [Option ID = 11141]

  40. 32) Radiolabelling of DNA with P32 radioisotope takes place at

    --- Content provided by‌ FirstRanker.com ---

    [Question ID = 2784]

    1. phosphodiester bonds [Option ID = 11135]
    2. none of these [Option ID = 11136]
    3. 3' end of DNA [Option ID = 11134]
    4. 5' end of DNA [Option ID = 11133]
    5. --- Content provided by​ FirstRanker.com ---

    Correct Answer :-

    5' end of DNA [Option ID = 11133]

  41. 33) Tendency of cells to form colonies is increased by

    [Question ID = 2783]

    --- Content provided by‌ FirstRanker.com ---

    1. incubation with calcium chelators [Option ID = 11132]
    2. inhibiting intracellular calcium [Option ID = 11131]
    3. inhibiting extracellular calcium [Option ID = 11129]
    4. increasing extracellular calcium [Option ID = 11130]

    Correct Answer :-

    --- Content provided by​ FirstRanker.com ---

    increasing extracellular calcium [Option ID = 11130]

  42. 34) The enzyme lactate dehydrogenase converts [Question ID = 2812]

    1. lactate to acetaldehyde [Option ID = 11246]
    2. pyruvate to lactate [Option ID = 11245]
    3. --- Content provided by​ FirstRanker.com ---

    4. pyruvate to acetaldehyde [Option ID = 11247]
    5. acetaldehyde to acetic acid [Option ID = 11248]

    Correct Answer :-

    pyruvate to lactate [Option ID = 11245]

  43. --- Content provided by​ FirstRanker.com ---

  44. 35) How many pi molecular orbitals are present in hexatriene?

    [Question ID = 2815]

    1. 5 [Option ID = 11258]
    2. 4 [Option ID = 11257]
    3. 12 [Option ID = 11260]
    4. --- Content provided by FirstRanker.com ---

    5. 6 [Option ID = 11259]

    Correct Answer :-

    6 [Option ID = 11259]

  45. 36) How many molecular orbitals are formed by combining 4 atomic orbitals?

    --- Content provided by⁠ FirstRanker.com ---

    [Question ID = 2820]

    1. 4 [Option ID = 11279]
    2. 2 [Option ID = 11277]
    3. 3 [Option ID = 11278]
    4. 8 [Option ID = 11280]
    5. --- Content provided by‍ FirstRanker.com ---

    Correct Answer :-

    4 [Option ID = 11279]

  46. 37) To determine the stability of protein "A" under stimulus of hormone to cells, which of the following experiments should be carried out?

    [Question ID = 2781]

    --- Content provided by‌ FirstRanker.com ---

    1. Cell should be grown in the presence and absence of hormone. After different time intervals, protein is isolated and fractionated on SDS-PAGE and western blot performed [Option ID = 11122]
    2. Purified protein A should be incubated with hormone for different time intervals. Do SDS-PAGE followed by western to see how much protein is present [Option ID = 11124]
    3. Extract total protein from the cell. In one tube add hormone and in another tube add buffer. Carry out western blotting for the protein A, using specific antibodies at different time intervals. [Option ID = 11121]
    4. Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]

    Correct Answer :-

    --- Content provided by‍ FirstRanker.com ---

    Culture the cells in the presence and absence of hormones for 48hrs. Now add cyclohexamide and incubate cells again for different times (2-4 hrs etc). Isolate the total protein and do western blot for the protein A. [Option ID = 11123]

  47. 38) In an experiment to detect DNA methylation in regulatory region of globin gene, which of the following method is recommended?

    [Question ID = 2790]

    1. PCR amplification and sequencing [Option ID = 11157]
    2. --- Content provided by⁠ FirstRanker.com ---

    3. Restriction enzyme digestion and southern hybridization [Option ID = 11160]
    4. Digestion with methylated sensitive restriction enzyme and electrophoresis [Option ID = 11158]
    5. Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]

    Correct Answer :-

    Digestion with methylation sensitive restriction enzyme and southern hybridization [Option ID = 11159]

    --- Content provided by‍ FirstRanker.com ---

  48. 39) In a population from a recently discovered island in the Indian ocean, most of the people were of blood group O. This indicates that [Question ID = 2804]

    1. This a case of pseudo-genes [Option ID = 11215]
    2. This is a case of pseudo-dominance [Option ID = 11216]
    3. This is due to high rate of mutation [Option ID = 11214]
    4. --- Content provided by‌ FirstRanker.com ---

    5. Blood group O is a truly dominant allele [Option ID = 11213]

    Correct Answer :-

    This is a case of pseudo-dominance [Option ID = 11216]

  49. 40) Which phospholipid inhibits the release of Cytochrome c from the mitochondria?

    --- Content provided by⁠ FirstRanker.com ---

    [Question ID = 2785]

    1. Cardiolipin [Option ID = 11139]
    2. Phosphatidyl serine [Option ID = 11137]
    3. Phosphatidyl choline [Option ID = 11138]
    4. None of these [Option ID = 11140]
    5. --- Content provided by‍ FirstRanker.com ---

    Correct Answer :-

    Cardiolipin [Option ID = 11139]

  50. 41) Which cytokine is primarily responsible for auto immune response?

    [Question ID = 2800]

    --- Content provided by FirstRanker.com ---

    1. IL-1 [Option ID = 11199]
    2. IL-17 [Option ID = 11200]
    3. IL-10 [Option ID = 11197]
    4. IL-5 [Option ID = 11198]

    Correct Answer :-

    --- Content provided by​ FirstRanker.com ---

    IL-17 [Option ID = 11200]

  51. 42) Which of the following is true, if carbonyl (C=O) group of ith residue in a polypeptide chain hydrogen bonds with i+n residue, where [Question ID = 2806]

    1. n=4 is a p- helix [Option ID = 11222]
    2. n=3 is an alpha helix [Option ID = 11223]
    3. --- Content provided by FirstRanker.com ---

    4. n=2, peptide degenerates to a non chiral, 2, 27 helical ribbon [Option ID = 11221]
    5. n=5 is a 3.613 helix [Option ID = 11224]

    Correct Answer :-

    n=2, peptide degenerates to a non chiral, 2, 27 helical ribbon [Option ID = 11221]

  52. --- Content provided by‌ FirstRanker.com ---

  53. 43) Which of the following is NOT a part of the primary proteins structure?

    [Question ID = 2794]

    1. The disulphide linkages [Option ID = 11174]
    2. The amino acid sequences [Option ID = 11173]
    3. The conformation of the polypeptide backbone [Option ID = 11176]
    4. --- Content provided by‍ FirstRanker.com ---

    5. The planar nature of the amide linkage [Option ID = 11175]

    Correct Answer :-

    The disulphide linkages [Option ID = 11174]

  54. 44) Which of the following metal ions is used for the treatment of arthritis?

    --- Content provided by‍ FirstRanker.com ---

    [Question ID = 2818]

    1. Magnesium [Option ID = 11272]
    2. Copper [Option ID = 11

      This download link is referred from the post: DUET Last 10 Years 2011-2021 Question Papers With Answer Key || Delhi University Entrance Test conducted by the NTA

    3. --- Content provided by​ FirstRanker.com ---