Download MBBS 2nd Year 2022 August 526061 Pharmacology I Mcqs MCQs Question Paper

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[MBBS 0822] AUGUST 2022 Sub. Code :6061

M.B.B.S. DEGREE EXAMINATION

(For the candidates admitted from the Academic Year 2019-2020)

SECOND YEAR - SUPPLEMENTARY (CBME)

PAPER I - PHARMACOLOGY -1

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O.P. Code: 526061

Time: 30 Minutes Maximum : 20 Marks

Answer All Questions

Choose one correct answer in the box provided in the Answer Script.

No overwriting should be done.

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II1. Multiple Choice Questions: (20x1=20)

1. Which of the following is not a Cytochrome P450 enzyme inducer
   1. Phenytoin
   2. Phenobarbitone
   3. Erythromycin
   4. Cigarette smoke

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2. Drugs with high Plasma Protein Binding have
   1. Short duration of action
   2. Less drug interactions
   3. Lower Volume of distribution
   4. all the above

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3. Which is a prodrug?
   1. Ampicillin
   2. Captopril
   3. Levodopa
   4. Phenytoin

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4. Anti-hypertensive drug causing erectile dysfunction
   1. Calcium channel blocker
   2. ACE inhibitor
   3. AT1 receptor antagonists
   4. B-blockers

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5. Pilocarpine induces
   1. Active miosis
   2. Passive miosis
   3. Active mydriasis
   4. Passive mydriasis

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6. Propanolol can be used in all except
   1. Thyrotoxicosis
   2. Variant angina
   3. Migraine
   4. HT

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7. Fenoldopam is used in the management of
   1. Hypertensive emergencies
   2. Congestive heart failure
   3. Migraine prophylaxis
   4. Tachyarrhythmia

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8. Mechanism of action of digitalis is
   1. Inhibits Na+K+ ATPase pump
   2. Inhibits Na+H+ ATPase pump
   3. Activates Na+Cl- pump
   4. Inhibits carbonic anhydrase

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9. Bilateral renal artery stenosis is a contraindication for which Antihypertensive drug?
   1. Beta-blockers
   2. Calcium channel blockers
   3. ACE inhibitors
   4. Diuretics

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10. All of the following are CNS stimulants except
    1. Amphetamines
    2. Benzodiazepines
    3. Cocaine
    4. Methylphenidate

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11. Which of the following drug is used as Transcranial patch for Parkinsons disease?
    1. Rotigotine
    2. Levodopa
    3. Selegiline
    4. Carbidopa

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12. The side effect of Phenytoin when its plasma concentration is above therapeutic level is
    1. Gum hypertrophy
    2. Hirsuitism
    3. Osteomalacia
    4. Ataxia

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13. Which statement is true about Carbamazepine?
    1. Used in Trigeminal neuralgia
    2. Carbamazepine is an enzyme inhibitor
    3. Can cause megaloblastic anaemia
    4. Drug of choice for Status epilepticus

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14. Which one of the following drugs is contraindicated in acute myocardial infarction.
    1. Morphine
    2. Pentazocine
    3. Nitroglycerin
    4. Beta Blockers

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15. Anti-craving agents for alcohol dependence are all except
    1. Lorazepam
    2. Acamprosat
    3. Topiramate
    4. Naltrexone

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16. What is the drug of choice for firstranker.compulsive disorder?
    1. Imipramine
    2. Fluoxetine
    3. Benzodiazepines
    4. Alprazolam

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17. Leukotriene receptor antagonist.used for bronchial asthma is
    1. Zileuton
    2. Cromolynsodium
    3. Zafirlukast
    4. Aminophylline

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18. Preconceptional intake of which reduces the incidence of neural tube defects?
    1. Folic acid
    2. Vitamin A
    3. Vitamin C
    4. Vitamin E

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19. Filgrastim is used for treatment of
    1. Neutropenia
    2. Anaemia
    3. Polycythaemia
    4. Neutrophilia

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20. Absolute contraindication to thrombolytic therapy is
    1. Pregnancy
    2. History of haemorrhagic stroke in past one year
    3. Patient on nitrates
    4. hypertension.

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