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THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[MBBS 0822] AUGUST 2022 Sub. Code : 6063
M.B.B.S. DEGREE EXAMINATION
(For the candidates admitted from the Academic Year 2019-2020)
SECOND YEAR ? SUPPLEMENTARY (CBME)
PAPER V ? PATHOLOGY ? I
Q.P. Code: 526063
Time: 30 Minutes
Maximum : 20 Marks
Answer All Questions
Choose one correct answer in the box provided in the Answer Script. No overwriting
should be done.
III. Multiple Choice Questions:
(20 x 1 = 20)
1. Damage to nuclear DNA triggers this pathway
a. WNT signalling b. P53 c. AKT signalling d. Ubiquitin
2. Atrophy is decreased protein synthesis due to
a. Ubiquitin proteosome pathway b. WNT signalling
c. AKT pathway d. P53
3. Neutrophil extracellular traps are mainly produced by
a. Chemical carcinogens b. Infectious pathogens
c. Parasites d. Radiation insult
4. The most important cytokine for synthesis of connective tissue proteins is
a. MMPs b. VEGF c. TGF- d. IL-1
5. Heparin induced Thrombocytopenia syndrome is due to administration of
a. Unfractionated Heparin b. Fractionated Heparin
c. LMW Heparin d. Thrombin
6. Which of these diseases listed is a X-Linked disorder
a. Tay sach's disease b. Duchenne muscular dystrophy
c. Cystic fibrosis d. Haemophilia A
7. Familial hypercholesterolemia is caused by mutations in the gene encoding the
receptor for
a. HDL b. VLDL c. LDL d. Chylomicrons
8. FISH uses one of the following probes for recognising sequences in a chromosomal
region
a. RNA b. DNA c. CGH Probes d. SNP Probes
9. Class II MHC present antigens derived from
a. Extracellular microbes b. Intracellular microbes
c. Cytoplasmic proteins d. Tumour antigens
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10. In Acute antibody mediated Rejection antibodies bind to
a. CD3+ cells b. CD2+ cells
c. Vascular endothelium d. Tissue epithelium
11. The direct cytopathic effect of the replicating HIV results in
a. Loss of CD8+ cells b. Loss of CD4+ cells
c. Raised CD4+ cells d. Raised CD8+ cells
12. A sentinel lymph node is defined as
a. First node in a regional lymphatic basin receiving lymph flow from the primary
tumour
b. First node in another regional lymphatic basin receiving lymph flow from the
primary tumour
c. Second node in a regional lymphatic basin receiving lymph flow from the primary
tumour
d. Second node in another regional lymphatic basin receiving lymph flow from the
primary tumour
13. The downstream pathway components of RAS in cancer cells include
a. WNT b. NOTCH c. MAPK d. INK
14. The UV portion of the solar spectrum which is carcinogenic is
a. UVA b. UVB c. UVC d. Ozone portion
15. EBV is associated with
a. X-Linked agammaglobulinemia b. Nasopharyngeal carcinoma
c. Leukemia d. Melanomas
16. The novel covid-19 virus is
a. SARS-CoV-1 b. SARS-CoV-2 c. SARS-CoV-3 d. SARS-CoV-4
17. Meyers-kouwenaar bodies are seen in
a. Malaria b. Filaria c. Leishmania d. Taenia
18. The photochemical reaction for the the endogenous production of 7-dehydrocholesterol
requires solar UV Light in the range of
a. 290-315nm b. 320-360nm c. 370-400nm d. 410-425nm
19. The commonest age group of children affected by Teratoma is
a. 0-4 yrs b. 5-9 yrs c. 10-14 yrs d. 12-14yrs
20. The diagnosis of AML requires atleast
a. 50% blasts in bone marrow b. 40% blasts in bone marrow
c. 30% blasts in bone marrow d. 20% blasts in bone marrow.
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[MBBS 0822]
This post was last modified on 30 November 2024