FEBRUARY 2023 Sub. Code :6066
M.B.B.S. DEGREE EXAMINATION
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(For the candidates admitted from the Academic Year 2019-2020)
SECOND YEAR - (CBME)
PAPER III - MICROBIOLOGY - II
O.P. Code: 526066
Time: Three hours Maximum : 100 Marks (80 Theory +20MCQS)
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Answer all the Questions
I. Essay: (2x15=30)
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A 5 year old male child admitted in ICU with c/o fever, headache and chills. His mother complained that child is not able to stand 5 days after the onset of fever. O/E there is flaccid paralysis of lower limbs and tripod sign is elucidated. On CSF analysis glucose level and protein level is normal. Microscopic examination of CSF show 25-40 lymphocytes per microlitre and no bacteria seen. Ziehl — Neelsen staining of CSF is negative for Acid Fast bacilli.
- Mention the organism causing the disease. Enumerate the other organisms causes myelitis.
- Write in detail about the clinical manifestation, Lab diagnosis of disease.
- Describe prophylaxis of the causative organism.
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A 45 year old male patient attend O.P. with H/O fever with chills, headache abdominal pain with vomiting. History was elicited, that he went to Andaman and has taken drinking water from a lake. On examination there is jaundice with Hepato splenomegaly.". On dark ground microscopic examination of blood shows spirally coiled bacilli:
- What is the causative bacteria and write its pathogenesis.
- Describe the lab diagnosis and management of the disease.
- Write the preventive measures of it.
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II. Write Short notes on: (10 x5=50)
- Explain blood culture method for detection of Infective Endocarditis.
- Write the current definition and etiology of fever of unknown origin.
- Write short notes on drug resistance in Typhoidal Salmonella.
- Short note on Scrub typhus.
- Explain the pathogenesis and the diagnosis of dengue fever.
- Write the lab diagnosis of diarrhoea caused by coccidian parasite.
- How will you diagnose Respiratory tract Infection caused by Aspergillus.
- Describe the structure of SARS CoV -2.
- Describe the life cycle of Echinococcus granulosus
- Write the prophylaxis of whooping cough.
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