Download PTU M.Pharm 2020 March 2nd Sem 74962 Advanced Biopharmaceutics And Pharmacokinetics Question Paper

Download PTU (I.K. Gujral Punjab Technical University Jalandhar (IKGPTU) M.Pharma 2020 March (Master of Pharmacy) 2nd Sem 74962 Advanced Biopharmaceutics And Pharmacokinetics Previous Question Paper

1 | M-74962 (S31)-964

Roll No. Total No. of Pages : 01
Total No. of Questions : 06
M.Pharmacy (Pharmaceutics) (2017 Batch) (Sem.?2)
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS
Subject Code : MPH-202
M.Code : 74962
Time : 3 Hrs. Max. Marks: 75
INSTRUCTIONS TO CANDIDATES :
1. Attempt any FIVE questions out of SIX questions.
2. Each question carries FIFTEEN marks.

1. a) Discuss the physico-chemical factors influencing drug dissolution from dosage forms.
(7.5)
b) Give an account of Tight Junction Complex and its role in drug transport through the
intestine. (7.5)
2. a) Explain pH-partition hypothesis for predicting drug absorption. (7.5)
b) Give an account of IVIVC methods and their utility. (7.5)
3. a) Distinguish one compartment from two compartment model. Derive a simple
equation for predicting the plasma drug concentration for one compartment open
model after IV bolus injection. (7.5)
b) Write a note on CyP 450 based interactions. (7.5)
4. a) What are biosimilars? Briefly explain biosimilars and their general compendial
requirements. (7.5)
b) Give an account of the study designs used for bioequivalence assessment of drug
products. (7.5)
5. a) What is non-linear pharmacokinetics? Mention the reasons for this behavior with
suitable examples. (7.5)
b) Discuss briefly the methods used for assessing permeability of drug molecules in
vitro. (7.5)
6. Write short notes on :
a) Generic substitution with examples (5)
b) Pharmacokinetics of peptides (5)
c) Immunotherapy and its modules (5)
NOTE : Disclosure of Identity by writing Mobile No. or Making of passing request on any
page of Answer Sheet will lead to UMC against the Student.
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