Download OU B.Pharma 3-1 Year 2019 6157NON CBCS Physical Pharmacy I Question Paper

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Code No. 6157/Non-CBCS

FACULTY OF PHARMACY

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B. Pharmacy 3/4 I-Sem. (Non-CBCS) (Backlog) Examination, January 2020

Subject: Physical Pharmacy - I

Time: 3 Hours Max. Marks: 70

Note: Answer all questions. All questions carry equal marks.

1. (a) Write and explain the postulates of the kinetic molecular theory. 7
   

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   (b) Write the importance of polymorphism with examples and its applications. 7

   OR

2. (a) What is phase rule? Explain the phase diagram for two component systems. 9
   (b) Write a note on Differential Scanning Calorimetry with applications. 5
3. (a) Define i) Specific heat & Latent heat ii) Enthalpy iii) Entropy 6
   

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   (b) State and explain first and second law of thermodynamics with applications. 8

   OR

4. (a) Define and explain Hess’s law of heat summation and its application. 8
   (b) Explain Gibbs free energy and applications. 6
5. (a) What are colligative properties? Explain suitable colligative properties for molecular weight determination. 8
   

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   (b) Discuss the modern theory of strong electrolytes and Debye-Huckel theory. 6

   OR

6. (a) Explain Arrhenius theory of electrolytic-dissociation. 5
   (b) Derive the equation for determination of acidity & basicity constant and write its use. 9
7. (a) Define "buffer.” Derive buffer-equation for weak acids. 4
   

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   (b) What are the methods for adjustment of tonicity? Explain freezing point depression method for adjusting isotonicity. 10

   OR

8. (a) Derive Henderson-Hasselbalch buffer equation for a weak acid and its salt. 7
   (b) Write a note on pharmaceutical buffers and their preparation. Influence of pH on tissue irritation. 7
9. (a) Explain different types of electrodes. 9
   

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   (b) How to measure the EMF of cells. 5

   OR

10. (a) Draw and explain Daniel cell. 5
    (b) Write a note on: (i) Catalysis and Catalyst (ii) Promoters and Inhibitors (iii) Applications of Redox potentials in pharmacy. 9

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