MODEL PAPER FOR ANNUAL 2009
Pharmacology and Therapeutics
--- Content provided by FirstRanker.com ---
(Multiple Choice Questions)
Total Marks: 65
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Time Allowed: 1 hour 05 Minutes
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Q.1
A 20 year old male suffered from moderate Aspirin toxicity; he may be
--- Content provided by FirstRanker.com ---
managed by promoting its excretion when infused with:
a) Ascorbic acid.
--- Content provided by FirstRanker.com ---
b) Acid citrate.c) Sodium bicarbonate.
d) Sodium chloride.
--- Content provided by FirstRanker.com ---
e) Quinidine sulphate.
Q.2
--- Content provided by FirstRanker.com ---
A 15 year old boy needs to be avoided from the central effects of the drugs;
therefore he should be given some quaternary amine drug which has the
--- Content provided by FirstRanker.com ---
structure like:a)
--- Content provided by FirstRanker.com ---
b)
--- Content provided by FirstRanker.com ---
c)
--- Content provided by FirstRanker.com ---
d)--- Content provided by FirstRanker.com ---
e)Q.3
--- Content provided by FirstRanker.com ---
A 25 year old female was given 200mg of a drug I/V in a single dose;
during first 120 minutes its 100mg were eliminated. As this drug follows
--- Content provided by FirstRanker.com ---
first-order elimination kinetics, after 6 hours the amount of the drug leftbehind in the blood will be:
a) None.
--- Content provided by FirstRanker.com ---
b) 5 mg.
c) 15 mg.
--- Content provided by FirstRanker.com ---
d) 25 mge) 35 mg.
--- Content provided by FirstRanker.com ---
Q.4A 2 month child accidentally got a dose of chloramphenicol which may be
harmful to him due to low enzymatic activity. It is metabolised through
--- Content provided by FirstRanker.com ---
phase-I reaction like:
a) Acetylation.
--- Content provided by FirstRanker.com ---
b) Reduction.c) Sulfation.
d) Methylation.
--- Content provided by FirstRanker.com ---
e) Glucoronidation.
--- Content provided by FirstRanker.com ---
Q.5
A single 10 mg dose of Enalapril was given to a hypertensive patient; after
--- Content provided by FirstRanker.com ---
first half life of 3 hours its plasma concentration was 50 ng/ml. To reach
almost 0.75 ng/ml it will take:
--- Content provided by FirstRanker.com ---
a) 9 hours.b) 15 hours.
c) 21 hours.
--- Content provided by FirstRanker.com ---
d) 27 hours.
e) 30 hours.
--- Content provided by FirstRanker.com ---
Q.6
After synthesis in the cytoplasm, Acetylcholine is stored in the vesicles and
--- Content provided by FirstRanker.com ---
in each vesicle the "quanta" of acetylcholine molecules usually contain:a) 500 ? 1000 molecules.
b) 1000 ? 10,000 molecules.
--- Content provided by FirstRanker.com ---
c) 1000 ? 20,000 molecules.
d) 1000 ? 50,000 molecules.
--- Content provided by FirstRanker.com ---
e) 1000 ? 100,000 molecules.Q.7
--- Content provided by FirstRanker.com ---
Extensive research up till now on the adrenergic receptors has shown thatthe endothelium of the blood vessels contains:
a) 1 - receptors.
--- Content provided by FirstRanker.com ---
b) 2 - receptors.
c) 1 ? receptors.
--- Content provided by FirstRanker.com ---
d) 2 ? receptors.e) No adenoceptors.
Q.8
--- Content provided by FirstRanker.com ---
A 30 year old asthmatic patient is having mild to moderate hypertension;
he may be best managed by a good beta-blocker, like:
--- Content provided by FirstRanker.com ---
a) Atenolol.b) Nadolol.
c) Pindolol.
--- Content provided by FirstRanker.com ---
d) Propranolol.
e) Timolol.
--- Content provided by FirstRanker.com ---
Q.9
A 60 year old male patient wit a history of postural hypotensive attacks is
--- Content provided by FirstRanker.com ---
in need of an 1A ? specific blocker for his benign prostatic hyperplasmalike:
a) Prazosin.
--- Content provided by FirstRanker.com ---
b) Terazosin.c) Doxazosin.
d) Tamsulosin
--- Content provided by FirstRanker.com ---
e) Alfuzosin.
Q.10 An accidental overdosage of Chlordiazepoxide was observed in a 6 year old
--- Content provided by FirstRanker.com ---
child; he may be best treated by giving him an antagonist like:
a) Flumazenil.
--- Content provided by FirstRanker.com ---
b) Naloxone.c) Fomepizole.
d) Nalorphine.
--- Content provided by FirstRanker.com ---
e) Naltrexone.
Q.11 A 40 year old male was under alcoholism and apart from an increased risk
--- Content provided by FirstRanker.com ---
of severe liver disease he may be at an increased risk for:
a) Angina.
--- Content provided by FirstRanker.com ---
b) Heart failure.c) Pulmonary hypertension.
d) Renal impairment.
--- Content provided by FirstRanker.com ---
e) CNS-tumours.
--- Content provided by FirstRanker.com ---
Q.12 A 60 year old lady who was undergoing a cardiac surgery got an agent
which provided full analgesia without any cardiac effect; but the patient
--- Content provided by FirstRanker.com ---
was having full awareness during surgery with recall after it. Most probably
she got:
--- Content provided by FirstRanker.com ---
a) Ketamine.b) Enflurane.
c) Fentanyl.
--- Content provided by FirstRanker.com ---
d) Thiopental.
e) Midazolam.
--- Content provided by FirstRanker.com ---
Q.13 Lidocaine, an amide was injected in an infected tissue to get a local
anaesthesia; its pKa is 7.9; 90% of the drug converted in an ionized state
--- Content provided by FirstRanker.com ---
because the tissue pH was:a) 6.9.
b) 5.9.
--- Content provided by FirstRanker.com ---
c) 4.9.
d) 3.9.
--- Content provided by FirstRanker.com ---
e) 2.9.Q.14 A young girl of 15 years old experiences epileptic fits during her menstrual
--- Content provided by FirstRanker.com ---
periods. She may however be managed with:a) Ethosuximide.
b) Valproic acid.
--- Content provided by FirstRanker.com ---
c) Phenytoin.
d) Corticosteroids.
--- Content provided by FirstRanker.com ---
e) Acetazolamide.Q.15 In the management of opioid withdrawal states the drugs usually used are
--- Content provided by FirstRanker.com ---
those which have:a) Short duration of action.
b) Long duration of action.
--- Content provided by FirstRanker.com ---
c) Pure antagonistic activity.
d) Euphoric effects also.
--- Content provided by FirstRanker.com ---
e) Mixed agonist-antagonistic activity.Q.16 A 35 year old depressive patient who was taking a tricyclic Antidepressant
--- Content provided by FirstRanker.com ---
also got clonidine to manage his hypertension. The possible druginteractions may show:
a) Re-appearance of depressive symptoms.
--- Content provided by FirstRanker.com ---
b) Increased respiratory depression.
c) Increased blood pressure.
--- Content provided by FirstRanker.com ---
d) Decreased blood pressure.e) Increased anticholinergic activity.
--- Content provided by FirstRanker.com ---
Q.17 A 50 year old woman with a history of peptic ulcer disease is suffering fromearly stages of Rheumatoid Arthritis. She may be better managed with:
a) Penicillamine.
--- Content provided by FirstRanker.com ---
b) Methotrexate.
c) Omeprazole.
--- Content provided by FirstRanker.com ---
d) Celecoxib.e) Indomethacin.
--- Content provided by FirstRanker.com ---
Q.18 Paracetamol is almost free of anti-inflammatory effect; its analgesicmechanism of action is:
a) Selective COX-2 inhibition.
--- Content provided by FirstRanker.com ---
b) Non-Selective COX 1 & 2 inhibition.
c) COX-3 inhibition in CNS.
--- Content provided by FirstRanker.com ---
d) Low CO2 levels at Spinal Cord.e) Decreased levels of Substance-P.
--- Content provided by FirstRanker.com ---
Q.19 In those patients with a history of GIT upset due to various NSAIDS, one ofthe followings may be better tolerated comparatively:
a) Aspirin.
--- Content provided by FirstRanker.com ---
b) Indomethacin.
c) Ibuprofen.
--- Content provided by FirstRanker.com ---
d) Diclofenace sodium.e) Naproxen.
--- Content provided by FirstRanker.com ---
Q.20 A 35 year old patient suffering from Chronic Gout needs increased urinaryexcretion of uric acid; one of the followings will be effective even if he is
having renal insufficiency:
--- Content provided by FirstRanker.com ---
a) Probenecid.
b) Sulfinpyrazone.
--- Content provided by FirstRanker.com ---
c) Allopurinol.d) Colchicine.
e) Benzbromarone.
--- Content provided by FirstRanker.com ---
Q.21 Sulfasalazine is also a disease-modifying anti-rheumatic drug; it can show
anti-rheumatic action due to its active metabolite:
--- Content provided by FirstRanker.com ---
a) Sulfapyridine.
b) 5 ? aminosalicylic Acid.
--- Content provided by FirstRanker.com ---
c) Acetylsalicylic Acid.d) Hydroxysalicylic Acid.
e) Sodium Salicylic Acid.
--- Content provided by FirstRanker.com ---
Q.22 A 30 year old pregnant lady was diagnosed to be suffering from haemolytic
anaemia; no exact cause of it could be found except that of a history of
--- Content provided by FirstRanker.com ---
drug intake to control her hypertension. The most likely drug she took may
be:
--- Content provided by FirstRanker.com ---
a) Propranolol.b) Captopril.
c) Clonidine.
--- Content provided by FirstRanker.com ---
d) Methyldopa.
e) Hydralazine.
--- Content provided by FirstRanker.com ---
Q.23 A 55 year old male has been taking orally Nitroglycerin for any acute attack
of "Angina on Effort". But due to frequently occurring such attacks he must
--- Content provided by FirstRanker.com ---
be given some useful alternative like:a) Esmolol.
b) Amyl nitrite.
--- Content provided by FirstRanker.com ---
c) Diltiazem.
d) Isosorbide dinitrate sublingually.
--- Content provided by FirstRanker.com ---
e) Sublingual nitroglycerine.Q.24 To treat a case of chronic congestive cardiac failure a drug is to be selected
--- Content provided by FirstRanker.com ---
which can reduce the mortality also; but one of the followings can hardlyreduce the mortality like:
a) Spironolactone.
--- Content provided by FirstRanker.com ---
b) Captopril.
c) Enalapril.
--- Content provided by FirstRanker.com ---
d) Carvedilol.e) Digoxin.
--- Content provided by FirstRanker.com ---
Q.25 Lidocaine is an amide local anesthetic agent but also has useful anti-arrhythmic activity. Typically it:
a) Decreases resting potential.
--- Content provided by FirstRanker.com ---
b) Decreases abnormal automaticity.
c) Increases PR interval.
--- Content provided by FirstRanker.com ---
d) Increase contractility.e) Increases duration of action potential.
--- Content provided by FirstRanker.com ---
Q.26 A 40 year old hypertensive patient while taking anti-hypertensive drugssuffered from a precipitous fall in blood pressure and fainting on initial
administration. It is commonly seen with:
--- Content provided by FirstRanker.com ---
a) Nifedipine.
b) Prazosin.
--- Content provided by FirstRanker.com ---
c) Atenolol.d) Hydrochlorthiazide.
e) Verapamil.
--- Content provided by FirstRanker.com ---
Q.27 The possible interactions of ACE inhibitors and Spironolactone include:
a) Increased attacks of dry cough.
--- Content provided by FirstRanker.com ---
b) Allergic reactions.
c) Hyperkalemia.
--- Content provided by FirstRanker.com ---
d) Hyponatremia.e) Hypercalcemia.
--- Content provided by FirstRanker.com ---
Q.28 A 60 year old woman suffered from hyperchloremic metabolic acidosis dueto which she is complaining of paraesthesias and occasional nausea; this is
usually associated with:
--- Content provided by FirstRanker.com ---
a) Acetazolamide.
b) Hydrochlorthiazide.
--- Content provided by FirstRanker.com ---
c) Furosemide.d) Amiloride.
e) Mannitol.
--- Content provided by FirstRanker.com ---
Q.29 A 40 year old patient was admitted in a hospital emergency due to
postmyocardial infarction ? `Acute Pulmonary Edema'. He may be given:
--- Content provided by FirstRanker.com ---
a) Acetazolamide.
b) Hydrochlorthiazide.
--- Content provided by FirstRanker.com ---
c) Furosemide.d) Triamterene.
e) Mannitol.
--- Content provided by FirstRanker.com ---
Q.30 A 50 year old lady when given Alteplase have shown improvement for
ischemic stroke attack; however she must be put on one of the following
--- Content provided by FirstRanker.com ---
drugs to prevent recurrence of such attacks:
a) Aspirin.
--- Content provided by FirstRanker.com ---
b) Warfarin.c) Enoxaparin.
d) Urokinase.
--- Content provided by FirstRanker.com ---
e) Aminocaproic Acid.
Q.31 A 60 year old lady suffering from Deep Vein Thrombosis (DVT) in her left
--- Content provided by FirstRanker.com ---
thigh was well maintained on Warfarin but now suddenly reported back for
her severe nose-bleed. She must be immediately treated with:
--- Content provided by FirstRanker.com ---
a) Factor VIII.b) Vitamin K1.
c) Protamine.
--- Content provided by FirstRanker.com ---
d) Alteplase.
e) Aminocaproic Acid.
--- Content provided by FirstRanker.com ---
Q.32 A 50 year old male presents with striking hypertriglyceridemia; after about
6 months of drug treatment his "triglyceride and VLDL Cholesterol" levels
--- Content provided by FirstRanker.com ---
dropped dramatically but his "HDL Cholesterol" levels had doubled. Thisphenomenon is commonly seen with:
a) Lovastatin.
--- Content provided by FirstRanker.com ---
b) Gemfibrozil.
c) Niacin.
--- Content provided by FirstRanker.com ---
d) Colestipol.e) Ezetimibe.
Q.33 Although prescribed by a careless physician for ulcerative colitis but it is
--- Content provided by FirstRanker.com ---
hardly useful; the drug is:
a) Prednisone.
--- Content provided by FirstRanker.com ---
b) Methotrexate.c) Infliximab.
d) Azathioprine.
--- Content provided by FirstRanker.com ---
e) Loratadine.
Q.34 A 65 year old lady who is a known patient of Parkinsonism is also on anti-
--- Content provided by FirstRanker.com ---
cancer therapy; but to avoid their nauseating effects she must be kept
away from such a drug which may also cause extrapyramidal dysfunction
--- Content provided by FirstRanker.com ---
e.g:a) Dexamethasone.
b) Ondansetron.
--- Content provided by FirstRanker.com ---
c) Dronabinol.
d) Metoclopramide.
--- Content provided by FirstRanker.com ---
e) Prochlorperazine.Q.35 In an old age debilitated patient who is having chronic constipation with
--- Content provided by FirstRanker.com ---
severely reduced bowel tone may be benefited with:a) Castor oil.
b) Glycerine.
--- Content provided by FirstRanker.com ---
c) Mineral oil.
d) Magnesium hydroxide.
--- Content provided by FirstRanker.com ---
e) Phenolphthalein.Q.36 Diphenoxylate is an opioid derivative anti-diarrheal drug and it is usually
--- Content provided by FirstRanker.com ---
combined with Atropine to:a) Enhance its activity.
b) Reduce its CNS side effects.
--- Content provided by FirstRanker.com ---
c) Reduce the likelihood of abuse.
d) Make useful for children also.
--- Content provided by FirstRanker.com ---
e) Decrease the GIT secretions.Q.37 A 40 year old known asthmatic patient reported to emergency for his
--- Content provided by FirstRanker.com ---
severe exacerbations of asthma; he must get oxygen and frequentadministration of corticosteroid with:
a) Epinephrine.
--- Content provided by FirstRanker.com ---
b) Salbutamol.
c) Ipratropium.
--- Content provided by FirstRanker.com ---
d) Cromolyn.e) Zileuton.
--- Content provided by FirstRanker.com ---
Q.38 The life saving drug given parenterally in severe status asthmaticus will actby inhibiting Phospholipase A2:
a) Epinephrine.
--- Content provided by FirstRanker.com ---
b) Aminophylline.
c) Salbutamol.
--- Content provided by FirstRanker.com ---
d) Prednisone.e) Metaproterenol.
--- Content provided by FirstRanker.com ---
Q.39 A 55 year old patient suffering from persistent dry cough for the last 2months due to unknown reasons wants to get a drug without having
constipating effect like:
--- Content provided by FirstRanker.com ---
a) Codeine.
b) Dextromethorphan.
--- Content provided by FirstRanker.com ---
c) Pholcodein.d) Hydrocodone.
e) Physostigmine.
--- Content provided by FirstRanker.com ---
Q.40 After taking Aspirin a 25 year old patient suffered from severe
bronchospasm who may be now managed by giving:
--- Content provided by FirstRanker.com ---
a) Epinephrine.
b) Aminophyleine.
--- Content provided by FirstRanker.com ---
c) Loratedine.d) Zafirlukast.
e) Omalizumab.
--- Content provided by FirstRanker.com ---
Q.41 Minimum Bacterial Concentration (MBC) is the lowest concentration of any
antibiotic which kills the bacteria up to:
--- Content provided by FirstRanker.com ---
a) 90.0%.
b) 95.0%.
--- Content provided by FirstRanker.com ---
c) 98.0%.d) 99.0%.
e) 99.9%.
--- Content provided by FirstRanker.com ---
Q.42 To get the synergistic effect, all the -lactam antibiotics can be combined
with:
--- Content provided by FirstRanker.com ---
a) Macrolides.
b) Chloramphenicol.
--- Content provided by FirstRanker.com ---
c) Aminoglycosides.d) Quinolones.
e) Tetracyclines.
--- Content provided by FirstRanker.com ---
Q.43 A 30 year old female developed antibiotic-induced colitis due to C. difficile;
she was given Metronidazole to treat it but it proved ineffective. Now she
--- Content provided by FirstRanker.com ---
can respond to oral:
a) Amoxicillin.
--- Content provided by FirstRanker.com ---
b) Erythromycin.c) Chloramphenicol.
d) Doxycycline.
--- Content provided by FirstRanker.com ---
e) Vancomycin.
Q.44 Erythromycin is an older macrolide antibiotic which is different from its
--- Content provided by FirstRanker.com ---
newer family members like Azithromycin in that it has:
a) Longer half-life.
--- Content provided by FirstRanker.com ---
b) Lesser oral absorption.c) No active metabolite.
d) Good urinary excretion.
--- Content provided by FirstRanker.com ---
e) Larger lactone ring.
Q.45 The Mechanism of Action of Clindamycin is the same as that of:
--- Content provided by FirstRanker.com ---
a) Penicillin.
b) Erythromycin.
--- Content provided by FirstRanker.com ---
c) Tetracyclines.d) Ciprofloxacin.
e) Trimethoprim.
--- Content provided by FirstRanker.com ---
Q.46 In a 40 year old male the culture growth has shown the infection due to
Streptococcus Pneumoniae which is sensitive to Quinolones; being a known
--- Content provided by FirstRanker.com ---
patient of Severe Hepatitis, he must avoid to take:
a) Ciprofloxacin.
--- Content provided by FirstRanker.com ---
b) Norfloxacin.c) Levofloxacin.
d) Trovafloxacin.
--- Content provided by FirstRanker.com ---
e) Gatifloxacin.
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Q.47 A 16 year old girl has been recently diagnosed preliminary as a case ofPulmonary Tuberculosis after analysing her history, physical examination,
routine blood test and X-ray chest. Now after sending her sputum to the
--- Content provided by FirstRanker.com ---
laboratory for culture the most appropriate action will be:
a) Wait for the culture report.
--- Content provided by FirstRanker.com ---
b) Prescribe Isoniazide only.c) Give a combination of Isoniazide and Rifampin.
d) Hospitalize her and give Isonazide, Rifampin and Ethambutol.
--- Content provided by FirstRanker.com ---
e) Hospitalize her and give Isoniazide, Pyrazinamide and Amikacin.
Q.48 A 20 year old patient is suffering from an acute attack of malaria, his blood
--- Content provided by FirstRanker.com ---
film has shown P-vivax parasites; he got Chloroquine for this attack but to
avoid future relapses of such attacks he must be given:
--- Content provided by FirstRanker.com ---
a) Mefloquine.b) Quinine.
c) Primaquine.
--- Content provided by FirstRanker.com ---
d) Pyrimethamine - Sulfadoxine.
e) Proguanil.
--- Content provided by FirstRanker.com ---
Q.49 After getting a meal at a local restaurant a 25 year old patient suffered
from a mild to moderate amebiasis; while later on he developed amebic
--- Content provided by FirstRanker.com ---
liver abscess which should be treated by giving him:a) Emetine plus Diloxanide Furoate.
b) Diloxanide Furoate plus Iodoquinol.
--- Content provided by FirstRanker.com ---
c) Chloroquine.
d) Metronidazole followed by Paromomycin.
--- Content provided by FirstRanker.com ---
e) Iodoquinol alone.Q.50 Amphotericin B decreases the filtration rate and causes renal tubular
--- Content provided by FirstRanker.com ---
acidosis which can be reduced by:a) Reducing the dose.
b) Using corticosteroids.
--- Content provided by FirstRanker.com ---
c) Giving saline infusion.
d) Changing the route of administration.
--- Content provided by FirstRanker.com ---
e) Decreasing the rate of infusion.Q.51 Most of the systemically used anti-fungals are selectively toxic to fungi
--- Content provided by FirstRanker.com ---
because they inhibit:a) Cell wall synthesis.
b) RNA synthesis.
--- Content provided by FirstRanker.com ---
c) Transpeptidase.
d) Ergosterol.
--- Content provided by FirstRanker.com ---
e) Topoisomerase II.Q.52 A 35 year old woman suffering from Hepatitis-C viral infection has been
--- Content provided by FirstRanker.com ---
treated with proper treatment; but she developed a `flu-like' symptoms oninjection which are typically seen with:
a) Adefovir.
--- Content provided by FirstRanker.com ---
b) Lamivudine.
c) Ribavirin.
--- Content provided by FirstRanker.com ---
d) Interferon-.e) Amantadine.
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Q.53 A 30 year old woman underwent segmental mastectomy followed by
chemotherapy with cyclophosphamide; this drug characteristically may
--- Content provided by FirstRanker.com ---
cause:
a) GIT distress.
--- Content provided by FirstRanker.com ---
b) Myelosuppression.c) Alopecia.
d) Hemorrhagic cystitis.
--- Content provided by FirstRanker.com ---
e) Cardiac dysfunction.
Q.54 Methotrexate is an antagonist of folic acid and is a cell cycle-specific drug
--- Content provided by FirstRanker.com ---
which acts primarily in the:
a) G0 ? Phase.
--- Content provided by FirstRanker.com ---
b) G1 ? Phase.c) G2 ? Phase.
d) S ? Phase (DNA-Synthesis).
--- Content provided by FirstRanker.com ---
e) Mitotic Phase.
Q.55 A 25 year old man with Hodgkin's disease was successfully treated with
--- Content provided by FirstRanker.com ---
ABVD regimen; but later on he developed some pulmonary toxicity. This is
common with:
--- Content provided by FirstRanker.com ---
a) Adriamycin.b) Bleomycin.
c) Vincristine.
--- Content provided by FirstRanker.com ---
d) Dacarbazine.
e) Prednisone.
--- Content provided by FirstRanker.com ---
Q.56 A 25 year old lady is suffering from severe Thyrotoxicosis; after
chemotherapy she may be required to be prepared for surgical intervention
--- Content provided by FirstRanker.com ---
by using a drug which has most rapid onset of action:a) I131.
b) Ipodate.
--- Content provided by FirstRanker.com ---
c) Prophylthrouracil.
d) Methimazole.
--- Content provided by FirstRanker.com ---
e) Thyroglobulin.Q.57 A 40 year old male has developed signs and symptoms of Cushing's
--- Content provided by FirstRanker.com ---
Syndrome which is due to an adrenal tumor. He may be given a drug whichreduces the uncontrolled production of adrenal tumour:
a) Cortisol.
--- Content provided by FirstRanker.com ---
b) Betamethasone.
c) Ketoconazole.
--- Content provided by FirstRanker.com ---
d) Fludrocortisone.e) Triamcinolone.
--- Content provided by FirstRanker.com ---
Q.58 28 year old male is using high doses of Oxandrolone for the last fewmonths; he is at increased risk of:
a) Hirsutism.
--- Content provided by FirstRanker.com ---
b) Anemia.
c) Hyperprolactinemia.
--- Content provided by FirstRanker.com ---
d) Testicular Enlargement.e) Cholestatic Jaundice.
--- Content provided by FirstRanker.com ---
--- Content provided by FirstRanker.com ---
Q.59 A 15 year old boy with Type-I Diabetes Mellitus has been admitted in
--- Content provided by FirstRanker.com ---
emergency with Severe Hyperglycemia, Ketoacidosis and a blood pH of
about 7.1; the most appropriate drug to control rapidly the severe
--- Content provided by FirstRanker.com ---
Ketoacidosis is:a) Glyburide.
b) Tolbutamide.
--- Content provided by FirstRanker.com ---
c) Crystalline Zinc Insulin.
d) Isophane Insulin.
--- Content provided by FirstRanker.com ---
e) Ultralente Insulin.Q.60 A 45 year old patient of Type-II Diabetes is insisting to be managed with
--- Content provided by FirstRanker.com ---
monotherapy without having a pronounced risk of hypoglycaemia.Therefore he may be given:
a) Glipizide.
--- Content provided by FirstRanker.com ---
b) Glyburide.
c) Repaglinide.
--- Content provided by FirstRanker.com ---
d) Pioglitazone.e) Tolbutamide.
--- Content provided by FirstRanker.com ---
Q.61 An important adverse effect produced by Miglitol, an -glucosidase inhibitoris:
a) Post Prandial Hyperglycemia.
--- Content provided by FirstRanker.com ---
b) Edema.
c) Mild Anemia.
--- Content provided by FirstRanker.com ---
d) Flatulence and Abdominal Pain.e) Lactic acidosis.
--- Content provided by FirstRanker.com ---
Q.62 A 55 year old male patient of metastatic prostate cancer may be treatedwith some androgen receptor blockers like:
a) Flutamide.
--- Content provided by FirstRanker.com ---
b) Methyltestosterone.
c) Desogestrel.
--- Content provided by FirstRanker.com ---
d) Anastrozole.e) Oxandrolone.
--- Content provided by FirstRanker.com ---
Q.63 An 18 year old girl is very anxious before undergoing a tooth extraction.She is being allowed to lay down on a couch for another half an hour to
avoid one of the following possible effects of Promethazine:
--- Content provided by FirstRanker.com ---
a) Sedation.
b) Dryness of mouth.
--- Content provided by FirstRanker.com ---
c) Constipation.d) Orthostatic hypotension.
e) Blurring of vision.
--- Content provided by FirstRanker.com ---
Q.64 Cimetidine may have toxicity like:
a) Blurring of Vision.
--- Content provided by FirstRanker.com ---
b) Diarrhea.
c) Sedation.
--- Content provided by FirstRanker.com ---
d) Orthostatic Hypotension.e) Hepatic Enzymes Inhibition.
--- Content provided by FirstRanker.com ---
Q.65 Deferoxamine is a known chelator which has selectively high affinity for:a) Aluminium.
b) Lead.
--- Content provided by FirstRanker.com ---
c) Iron.
d) Arsenic.
--- Content provided by FirstRanker.com ---
e) Mercury.