MBBS SECOND PROFESSIONAL
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MODEL QUESTIONS FOR ANNUAL 2009General Pathology and Microbiology
(Multiple Choice Questions)
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Q.1
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A 22-year-old man develops marked right lower quadrant abdominal painover the past day. On physical examination there is rebound tenderness on
palpation over the right lower quadrant. Laparoscopic surgery is performed
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and the appendix is swollen, erythematous and partly covered by a
yellowish exudate. It is removed and a microscopic section shows
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infiltration with numerous neutrophils. The pain experienced by thispatient is predominantly the result of the formation of which of the
following two chemical mediators:
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a) Complement C3b and IgG
b) Interleukin-1 and Tumor Necrosis Factor
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c) Histamine and serotonind) Prostaglandin and bradykinin
e) Leukotriene and HPETE
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Q.2
A fifty year old woman, who is suffering from cirrhosis of the liver,
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presents with a distended abdomen to her physician, who taps the fluidand sends the specimen to the hospital laboratory for analysis. The fluid
shows protein content and specific gravity less than 3.0 gm/dl and 1.015
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respectively. The fluid is best described as:
a) Exudate
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b) Transudatec) Effusion
d) Isotonic fluid
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e) Serous fluid
Q.3
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A group of sailors was rescued from a ship that was lost for a month. They
lived on fish recovered from the sea. They were all fatigued and had gums
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bleeding on eating anything hard. What is the most likely cause?a) Scurvy
b) Vitamin K deficiency
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c) Ehlers-Danlos syndrome
d) Osteogenesis imperfecta
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e) Marfan syndromeQ.4
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A cholecystectomy specimen is examined fresh in the laboratory. It showsa large impacted gallstone in the neck. Fundus of the gallbladder shows
engorgement of blood vessels on external surface. This is most likely due
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to:
a) A malignant process
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b) Hemorrhagec) Hyperemia
d) Congestion due to obstruction to outflow of blood
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e) Chronic inflammation
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Q.5
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A 40 years injured male is presented in emergency with complaints ofincreased respiratory rate, cold extremities, rapid pulse and oliguria. On
examination B.P. is 60/40mmHg, Pulse 150/min and bluish discoloration of
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tip of tongue and nails. Which type of shock is developed in this patient?
a) Cardiogenic shock
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b) Neurogenic shockc) Hypovolemic shock
d) Septic shock
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e) DIC
Q.6
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A 60-year old businessman lived for 40 years in Egypt. On return to
Pakistan, he presents with painless gross haematuria. Cystoscopy was
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done by the urologist and the biopsy specimen obtained showedTransitional Cell Carcinoma. Urine examination shows pear shaped ova
with large terminal spine. Which of the following is most likely responsible
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for this tumor:
a) Schistosoma haematobium
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b) Schistosoma japonicumc) Schistosoma mansoni
d) Wuchereria bancrofti
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e) Trypanosoma cruzi.
Q.7
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A neonate was born with signs of encephalitis, chorioretinitis,
hepatosplenomegaly, fever and jaundice. The mother gave a history of
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fever two to three times during pregnancy. History taking revealed that shehas many cats as pet. On examination of neonate intra cranial calcifications
were found. IgM Ab titer was also raised. What is the most likely
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Microorganism responsible?
a) Pneumocystis carinii
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b) Toxoplasma gondiic) Cytomegalovirus
d) Treponema palladium
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e) Rubella virus
Q.8
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A forty year old man complains of upper abdominal pain, watery foul
smelling diarrhea and flatulence for the past two weeks. He drank spring
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water on a camping trip near Abbotabad. Trophozoites were found on stoolexamination.
Which is the most likely protozoan involved:
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a) Crytosporidium
b) Giardia lamblia
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c) Entamoeba colid) Trichomonas
e) Acanthamoeba
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Q.9
A male baby is born at 39 weeks gestation with a petechial rash, low
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birthweight, hepatosplenomegaly and bilateral cataracts. This is thought to
be due to an infection acquired while the baby was still in utero. Select the
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condition which is most likely to cause this clinical presentation:a) Cytomegalovirus
b) Group B streptococcus
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c) Rubella virus
d) Toxoplasma gondii
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e) Treponema pallidum--- Content provided by FirstRanker.com ---
Q.10 A forty year old woman, has blurred vision and slurred speech. She is
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afebrile. She is well known in her neighbourhood for her expertise in home
canned vegetables and fruits. The most likely cause of her illness is?
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a) Clostridium perfringens toxin acting on neuromuscular junctionb) Clostridium botulinum toxin acting on the neuromuscular junction
c) Clostridium botulinum toxin acting on the cranial nerves
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d) Clostridium difficile acting on the acetylcholine receptors
e) Clostridium botulinum toxin acting on the adrenergic receptors
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