Download Pharm D 5th Year 2019 Oct 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Question Paper

Download Pharm-D (Doctor of Pharmacy) 5th Year (Fifth Year) 2019 Oct 383827 Clinical Pharmacokinetics And Pharmacotherapeutic Drug Monitoring Previous Question Paper

[LP 827] OCTOBER 2019 Sub. Code: 3827

PHARM. ?D? AND PHARM. ?D? (POST BACCALAUREATE)
EGREE EXAMINATION
(2009-2010 Regulation)
FIFTH YEAR
PAPER III ? CLINICAL PHARMACOKINETICS &
PHARMACOTHERAPEUTIC DRUG MONITORING

Q.P. Code : 383827
Time : Three hours Maximum : 70 Marks

I. Elaborate on: (4 x 10 = 40)

1. Mention the indications of extracorporeal methods of drug removal. Explain
hemodialysis and peritoneal dialysis.

2. Explain the steps to be followed in drug dosage adjustments in renal impairment.

3. a) What are the indications of therapeutic drug monitoring?
b) Explain the elements of protocol of therapeutic drug monitoring.

4. Discuss the estimation of hepatic dysfunction and dosing of drugs. Write a note
on effect of hepatic disease on pharmacokinetics of drugs.

II. Write notes on: (6 x 5 = 30)

1. Write a note on markers of GFR.
2. Define pharmacogenetics. Mention the goals and benefits of pharmacogenetics.
3. Define drug interactions. Explain pharmacokinetic drug interactions.
4. Explain therapeutic drug monitoring of digoxin.
5. Explain Bayesian theory. Mention its merits and demerits.
6. Write a note on nomograms and tabulations in designing dosage regimen.
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