Median Nerve and its Lesions
Dr Mukesh Singla
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Learning Objectives1. Median nerve formation , root value and important
relations
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2. Motor and sensory supply
3. Important sites of injuries/entrapment of nerve
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4. Effects of injury of median nerve5. How to clinically test median nerve injury
MCQ
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Q 1.Regarding the median nerve, all are correctEXCEPT:
a. Arises from both the medial and lateral cords of the
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brachial plexus.
b. It crosses the brachial artery at the insertion of the
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coracobrachialis.c. In the cubital fossa, it lies lateral to the brachial
artery.
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d. It enters the hand in the carpal tunnel.
e. Injury of the nerve causes ape-like hand.
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MCQQ 1.Regarding the median nerve, all are correct
EXCEPT:
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a. Arises from both the medial and lateral cords of the
brachial plexus.
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b. It crosses the brachial artery at the insertion of thecoracobrachialis.
c. In the cubital fossa, it lies lateral to the brachial
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artery.
d. It enters the hand in the carpal tunnel.
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e. Injury of the nerve causes ape-like hand.Answer c
MCQ
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Q 2. A 40 year tailor complains of pain numbness andweakness of right hand for last 3 months. On
examination, there is hypoesthesia and atrophy of
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thenar eminence. Which of the following nerve is likely
to be involved?
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A Ulnar nerveB Median nerve
C radial nerve
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D Axillary nerve
MCQ
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Q 3 Injury to the median nerve in the arm would affectall of the following movements except:
A. Pronation of the forearm
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B. Flexion of the wrist
C. Flexion of the thumb
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D. Supination of the forearmAnatomy
? Mixed nerve (contain motor & sensory fibers).
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? Root value: C 5,6,7,8 & T1? Runs in the median plane of the forearm , so
its called median nerve
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MEDIAN NERVE
? Formation:from two roots from
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lateral cord[C(5),6,7]&
from medial cord(C8,T1) of
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brachial plexus
Before leaving axil a, C7 fibres
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conveyed by median nerve arehanded over to Ulnar nerve
? These two roots embrace the third
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part of axillary artery uniting
anterior or lateral to it
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In the arm
? Closely related to the
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brachial artery through outthe course in arm
? In the upper part it is
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lateral to artey
? In the middle part it
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crosses the artery fromlateral to medial side
? Remains on the medial
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side up to elbow
Branches in arm
? Branch to Pronator Teres just above elbow
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? Branch to brachial artery? Branch to elbow joint at or just below the
elbow
In the cubital fossa
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? Descends medial to
brachial artery
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? Posterior to bicipitalaponeurosis
? Anterior to brachialis,
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seperated by the
muscle from the elbow
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joint? Leaves the cubital fossa by passing
between two heads of pronator teres
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In the forearm? Enters the forearm between
the heads of pronator teres
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? Crosses the lateral side of
ulnar artery from which it is
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seperated by the deep headof pronator teres
? Gives branch to pronator
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teres while passing between
the two heads
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? Proceeds behind atendinous ridge
between the two heads
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of Flexor digitorum
superficialis and
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anterior to Flexordigitorum profundus
? Here it is accompanied
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by median artery, a
branch of anterior
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interosseous artery? About 5 cm
proximal to flexor
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retinaculum itbecomes
superficial
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? Here it lies
between the
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tendon ofpalmaris longus
and the flexor
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carpi radialis
muscle
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? Leaves the forearm and enters the palm of thehand by passing through the carpal tunnel deep to
flexor retinaculum
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Branches in the forearm? Muscular branches
to all the muscles
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in the
superficial and
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intermediate layer offorearm except one
(FCU) originate
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medially from nerve
just distal to elbow
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joint? Anterior interosseous
nerve: originate between
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two heads of pronator teres
? passes distally down the
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forearm with the anteriorinterosseous artery.
? Innervates the muscles of
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deep layer (FPL, lateral half
of FDP (for index and middle
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finger) and pronatorquadratus)
?Palmar cutaneous branch: starts just proximal to flexor
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retinaculum?Lateral branches - thenar skin and connecting branch to
the lateral cutaneous nerve of fore arm
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?Medial branches - central palmer skin and connecting
branch to the palmar cutaneous branch of the ulnar nerve
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? Communicating branch:multiple
?Arise in the proximal forearm
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? Pass medialy between FDP &FDS and behind the ulnar artery
to join the ulnar nerve
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Median nerve in hand? Proximal to flexor retinaculum it lies
between the tendons of FCR & FDS
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overlapped by palmaris longus
? Distally it lies between the retinaculum and
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the tendon in the retinaculum? Site of compression
? Distal to retinaculum nerve enlarges and
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flattens
? devides in to five or six branches
Branches in the hand
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Lateral branch: gives
Recurrent
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muscular branch-short and
stout, curls upwards
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over the distal border
of flexor retinaculum
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and FPL to supplythree thenar muscles
APB, FPB &OP
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? Three palmer digital
branches- First two
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supply the skin of thesides of the thumb ,its
web and distal part of
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its dorsal surface.
? Third supplies the skin
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of the radial side ofindex finger and the
first lumbrical muscle
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through its superficial
surface
? Medial branch: gives
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? Two common palmar digital
branches- lateral and
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medial which descend tothe interdigital clefts
between the index, middle
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and ring finger
? Each nerve divides again
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into two to supply adjacentsides of the fingers
? So in total it supplies skin of
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lateral three and half fingers
including the skin on the
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dorsal aspect of terminalphalanges
Injuries
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? High? Low
Median Nerve Lesion in Elbow Region ? High Lesion
? Damaged in
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supracondylar fracture
of humerus
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? Muscles af ected are:? Pronator muscles of
the forearm
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? All long flexors ofwrist and fingers
except FCU and
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medial half of FDP
Motor Effects:
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Wastingof thenar
? Loss of pronation. Hand is kept in
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eminence
supine position
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? Wrist shows weak flexion, andulnar deviation
? Loss of flexion on interphalangeal
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joints of the index and middle
fingers
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? Weak flexion of ring and littlefinger
Ulnar deviation
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? Thumb is adducted and lateral y
rotated, with loss of flexion of
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terminal phalanx and loss ofopposition
? Wasting of thenar eminence
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? Hand looks flat ened and
"apelike", and presents an inability
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to flex three most radial digitswhen asked to make a fist.
? Sensory Ef ects: Loss of
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sensation from:? The radial side of the palm
? Palmar aspect of the lateral
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3? fingers? Distal part of the dorsal
surface of the lateral 3?
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fingers
? Trophic Changes:
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? Dry and scaly skin? Easily cracking nails
? Atrophy of the pulp of
fingers
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Median Nerve Lesion at Wrist
? Often injured by penetrating wounds (stab wounds or
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broken glass) of the forearm.? Motor:
? Thenar muscles are paralyzed and atrophy in time so thenar
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eminence becomes flattened
? Opposition & abduction of thumb are lost, and thumb and
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lateral two fingers are arrested in adduction & hyperextensionposition .
? "Apelike hand"
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? Sensory & trophic changes are same as in elbowregion injuries
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Examination? Flexor pol icis longus : Tested by holding
thumb at its base and patient asked to flex the
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terminal phalanx
Examination
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? Flexor digitorum superficialis & profundus
(Ochsner's clasping test)
- Patient is asked to clasp the hands , the index
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finger of af ected side fails to flex
Examination
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? Flexor Carpi radialis : Hand deviates to theulnar side when flexed against resistance
Examination
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? Muscles of Thenar eminance:-abductor pol icis brevis (Pen test)
- hand laid flat on the table
-pen held above the palm and the patient is
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asked to touch the pen with his thumb
Examination
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? opponens pol icis : brings the tip of thethumb towards the tips of other fingers
Opponens pollices
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Benedict SignLesion to upper arm area, just proximal to where motor
branches of forearm flexors originate, is diagnosed if the
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patient is unable to make a fist.
More specifically, the patient's index and middle finger
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cannot flex at the MCP joint, while the thumb usually isunable to oppose. This is known as hand of benediction or
Pope's blessing hand.
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Benedict SignKiloh-Nevin syndrome and OK Sign
The Anterior Interosseus Nerve (AIN) syndrome
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Patients suffering from this syndrome have impaired distal
interphalangeal joint, because of which they are unable to
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pinch anything or make and "OK" sign with their index fingerand thumb. The syndrome can either happen from pinched
nerve, or even dislocation of the elbow.
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Kiloh-Nevin syndrome OK SignMCQ
After history of stab wound on front of forearm ,
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patient presents with impairment of the pincer
movement and is having difficulty picking up a small
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item, such as a coin, from a flat surface. Which of thefollowing statement is correct ?
A Injury to anterior interroseous nerve of median nerve
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B injury to main median nerve as pincer movement
involves FDS
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C Injury to ulnar nerveD. Injury to median nerve at level of wrist
Ape hand deformity
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In "Ape hand deformity", the thenar muscles becomeparalyzed due to impingement and are subsequently flattened.
it is seen only after the thenar muscles have atrophied. While
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the adductor pollicis remains intact, the flattening of the
muscles causes the thumb to become adducted and laterally
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rotated. The opponens pollicis causes the thumb to flex androtate medially, leaving the thumb unable to oppose.
Ape Thumb
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Median nerve CompressionSyndromes
? Carpal Tunnel ?nerve may be compressed due to
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inflammatory condition of ulnar bursa or anterior
dislocation of lunate bone
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? Pronator? Interosseous
Carpal Tunnel Syndrome
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? Compressive neuropathy as the nerve passes through theCarpal Tunnel
? Causes:
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- Idiopathic
: Most common
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- Inflammatory : Rheumatoid Arthritis: Wrist osteoarthritis
- Post traumatic : Bone thickening
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- Endocrine
: Myxoedema
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: Acromegaly- Pregnancy
- Gout
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- Repetitive wrist movts: Typists & Computer users
Carpal Tunnel Syndrome
? The commonest neurological
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problem associated with median
nerve is compression beneath
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flexor retinaculum at wrist.? Motor: Weak motor function of
thumb, index & middle finger
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? Sensory: Burning pain or `pins
and needles' along distribution
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of median nerve to lateral 3?fingers
No sensory changes over palm as palmer cutaneous branch
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is given before median nerve enters carpal tunnel.
Symptoms
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? Hand and wrist Pain? Paraesthesia
? Hypoaesthsia
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? Sparing of Palmar cutaneous branch supply
? Patient wakes at night with burning or aching
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pain and shakes the hand to obtain relief andrestore sensation
? Aggravated by elevation of hand
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? Thenar atrophy and weakness of thumb
opposition and abduction may develop late
Diagnosis
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? History
? Clinical examination:
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- Thenar wasting- Phalen's sign
- Tinel's sign
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- Carpal compression test
? Electro Diagnostic Studies:
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- Very reliable for evaluation- Atypical cases may be present
Thenar atrophy
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Phalen testA positive Phalen test is highly suggestive of carpal tunnel
syndrome.
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Phalen's test is performed by having patients place their wrists in
complete unforced flexion for at least 30 seconds.
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If the median nerve is entrapped at the wrist, this maneuver willreproduce the symptoms of carpal tunnel syndrome.
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Tinel's SignCarpal Compression test/ Durkan's test
Pronator teres syndrome
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? High Compression neuropathy? It is rare compared to CTS and AIS
Pronator teres syndrome
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The characteristic physical finding is tenderness over the
proximal median nerve, which is aggravated by resisted
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pronation of the forearm.The flexor pol icis longus and FDP of the index finger are weak,
leading to impairment of the pincer movement. This reflects
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involvement of the anterior interosseous nerve.
Sensory changes may be found in the first three fingers as well
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as in the palm, indicating impairment of the median nerveproximal to the flexor retinaculum.
Symptoms & signs
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? Symptoms are similar to those of carpal tunnel syndrome? Sensory disturbances
- Thumb & Index > Middle finger
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? Night pain is unusual and forearm pain is more common
? Hand numbness on gripping
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? Phalen's test negative? Double crush phenomena
? Symptoms provoked by resisted elbow flexion with forearm
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supinated ( tightening of bicipital aponeurosis )
? By resisted forearm pronation with the elbow extended (
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pronator tension )Thank You