FirstRanker Logo

FirstRanker.com - FirstRanker's Choice is a hub of Question Papers & Study Materials for B-Tech, B.E, M-Tech, MCA, M.Sc, MBBS, BDS, MBA, B.Sc, Degree, B.Sc Nursing, B-Pharmacy, D-Pharmacy, MD, Medical, Dental, Engineering students. All services of FirstRanker.com are FREE

📱

Get the MBBS Question Bank Android App

Access previous years' papers, solved question papers, notes, and more on the go!

Install From Play Store

Download MBBS Biochemistry PPT 43 Environmental Biochemistry Lecture Notes

Download MBBS (Bachelor of Medicine, Bachelor of Surgery) 1st year (First Year) Biochemistry ppt lectures Topic 43 Environmental Biochemistry Notes. - biochemistry notes pdf, biochemistry mbbs 1st year notes pdf, biochemistry mbbs notes pdf, biochemistry lecture notes, paramedical biochemistry notes, medical biochemistry pdf, biochemistry lecture notes 2022 ppt, biochemistry pdf.

This post was last modified on 05 April 2022

--- Content provided by FirstRanker.com ---

Unpol uted and Pol uted Environment

Do's and Don'ts To Maintain

Clean and Green Environment

--- Content provided by‍ FirstRanker.com ---


Contents

? What is an Environment?

--- Content provided by‍ FirstRanker.com ---

? Significance of an Environment on

Human Health

? Environmental Pol ution and Pol utants :

--- Content provided by FirstRanker.com ---


Types, Sources, Effects on human health

Control and Prevention

--- Content provided by FirstRanker.com ---


What Is An Environment ?
Features Of An Environment

? Next to Nutrition, Environment is most important

--- Content provided by⁠ FirstRanker.com ---


factor for human healthy life

? Environment is purely a natural entity where

--- Content provided by FirstRanker.com ---

human being in his living is surrounded with it.

? Environment of human being comprises of :

Atmosphere,air,water,soil,radiations,sound

--- Content provided by⁠ FirstRanker.com ---


,Temperature etc.

? Environment is directly and indirectly connected to

--- Content provided by FirstRanker.com ---

human body

? Natural environment is balanced and healthy

Environmental Entities

--- Content provided by FirstRanker.com ---


? Atmosphere

? Water

--- Content provided by FirstRanker.com ---

General

? physical structure

Oceans

--- Content provided by FirstRanker.com ---


? chemical composition

? composition, desalination

--- Content provided by‌ FirstRanker.com ---

Outer Atmosphere

? ozone - photochem,

Fresh water

--- Content provided by⁠ FirstRanker.com ---


Troposphere

? Sulfur, acid rain

--- Content provided by‌ FirstRanker.com ---

? Oxygen, water treatment

? CO

? NOx, smog

--- Content provided by‍ FirstRanker.com ---


? "Green Chemistry"

? CO2, H2O

--- Content provided by‍ FirstRanker.com ---

? Climate


Human Beings Leaders Of Universe

--- Content provided by FirstRanker.com ---

are Responsible For Maintaining State

Of An Environment


--- Content provided by​ FirstRanker.com ---

Significance Of An Environment On

Human Health


--- Content provided by FirstRanker.com ---

Close Relationship Of

Environment And Human Health


--- Content provided by​ FirstRanker.com ---

Environmental Pol utants




--- Content provided by‌ FirstRanker.com ---

Environmental Pol utants Directly

Affect Human Health

Toxicity Of Pol utants Depends Upon

--- Content provided by‍ FirstRanker.com ---


Amount,Duration,Potency

? Toxicity of pollutants is measured by dose and

--- Content provided by⁠ FirstRanker.com ---

response

? Dose: An amount that enters body of an exposed

organism

--- Content provided by‍ FirstRanker.com ---


? Response: An amount of damage caused by a

specific dose

--- Content provided by‌ FirstRanker.com ---

? LD50

? Lethal dose to 50% of test organisms
? Smaller LD50 more lethal is the chemical

--- Content provided by​ FirstRanker.com ---

? Determined for all new synthetic chemicals


Toxicity

--- Content provided by​ FirstRanker.com ---

? ED50

? Effective dose to 50% of test organisms
? ED50 causes 50% of population to exhibit whatever

--- Content provided by⁠ FirstRanker.com ---

effect is under study

? Dose-Response Curve

? Illustrates an effect of different doses on a

--- Content provided by‍ FirstRanker.com ---


population

? Threshold Level

--- Content provided by⁠ FirstRanker.com ---

? Maximum dose with no measurable effects


Environmental Pol utants and Disease

--- Content provided by⁠ FirstRanker.com ---

? Often difficult to

link pollutants to

their effects on

--- Content provided by‍ FirstRanker.com ---


people

? Persistence
? Bioaccumulation

--- Content provided by​ FirstRanker.com ---

? Biomagnification

Persistence

? A characteristic of certain chemicals that are

--- Content provided by​ FirstRanker.com ---


extremely stable and may take many years to

be broken down into simpler forms by natural

--- Content provided by⁠ FirstRanker.com ---

processes

? Synthetic chemicals (those not found in nature)
? Ex: DDT

--- Content provided by⁠ FirstRanker.com ---

? Natural decomposers (bacteria) have not

evolved a way to break it down


--- Content provided by​ FirstRanker.com ---

Bioaccumulation

? Buildup of a persistent toxic substance in an

organism's body, often in fatty tissues

--- Content provided by‍ FirstRanker.com ---




? Synthetic chemical do not metabolize well

--- Content provided by‍ FirstRanker.com ---

? They remain in body for extended periods of time

Biomagnification

? An increased

--- Content provided by FirstRanker.com ---


concentration of

toxic chemicals in

--- Content provided by‍ FirstRanker.com ---

tissues of organisms

that are at higher

levels in food webs

--- Content provided by⁠ FirstRanker.com ---


? Diagram is example

of biomagnification

--- Content provided by‌ FirstRanker.com ---

of DDT




--- Content provided by​ FirstRanker.com ---



Groupings of Chemical Pol utants:

Grouping

--- Content provided by​ FirstRanker.com ---


Grouped According to:

EDC (Endocrine Disrupting Chemical)

--- Content provided by FirstRanker.com ---

toxicological mode of action or

CMR (Carcinogenic, Mutagenic, toxic to

endpoint

--- Content provided by⁠ FirstRanker.com ---


Reproduction)

PBT (Persistent, Bioaccumulative Toxic)

--- Content provided by FirstRanker.com ---

environmental properties

vPvB (very Persistent, very Bioaccumulative)
POP (Persistent Organic Pollutant)

--- Content provided by FirstRanker.com ---

PPCPs

type of intended usage

priority pollutants and others

--- Content provided by‍ FirstRanker.com ---


legislation

"emerging" contaminants/pollutants

--- Content provided by​ FirstRanker.com ---

novelty, fad, timeliness, or new

concern

PPCPs as Environmental Pol utants

--- Content provided by‍ FirstRanker.com ---


? PPCPs are a diverse group of chemicals comprising all human and

veterinary drugs (available by prescription or over-the-counter;

--- Content provided by FirstRanker.com ---

including new genre of "biologics"

? Diagnostic agents (X-ray contrast media)

? Nutraceuticals (bioactive food supplements such as huperzine A)

--- Content provided by⁠ FirstRanker.com ---


? Fragrances,Perfumes,Deos Sprays (e.g., musks)

? Sun-screen agents (e.g., 4-methylbenzylidene camphor

--- Content provided by‌ FirstRanker.com ---

octocrylene)

? Excipients (so called "inert" ingredients used in PPCP

manufacturing and formulation; e.g., parabens)

--- Content provided by FirstRanker.com ---



Mechanism of

Environmental Pol utants

--- Content provided by‍ FirstRanker.com ---


? Environmental pol utant of physical, chemical or

biological origin

--- Content provided by FirstRanker.com ---

? Interacts with various biomolecules of human body

as per specific affinity

? Accumulate in cel s and tissues

--- Content provided by‌ FirstRanker.com ---


? Disturb biomolecule structural features

? Distract biomolecules from true function

--- Content provided by​ FirstRanker.com ---

? Loads immune system, liver and kidneys

? Alter normal health

? Leads to il -effects/disorders- Anemia,Cancers

--- Content provided by FirstRanker.com ---




Endocrine Disrupters

--- Content provided by‌ FirstRanker.com ---

? A chemical that mimics or interferes with the actions of

the endocrine system in humans and wildlife

? i.e. It effects the ability of the hormones in the organisms to

--- Content provided by FirstRanker.com ---


function properly

? Examples include:

--- Content provided by​ FirstRanker.com ---

? PCBs, Dioxins
? Heavy metals ? lead and mercury
? DDT

? Animals exposed to these chemicals have altered

--- Content provided by‌ FirstRanker.com ---


reproductive development and are often sterile

Endocrine Disrupters and Humans

--- Content provided by⁠ FirstRanker.com ---

? Infertility and hormonally related cancers are

increasing

? Breast cancer and testicular cancer

--- Content provided by⁠ FirstRanker.com ---


? Phthalates have been implicated as potential

endocrine disrupters

--- Content provided by‍ FirstRanker.com ---

? Common ingredient in: cosmetics, fragrances, nail

polish, medication, toys, food packaging

? Cannot make a link between endocrine

--- Content provided by​ FirstRanker.com ---


disrupters and human illness

? Too few studies have been performed
Determining Health Effects of Pol utants

--- Content provided by​ FirstRanker.com ---


? Toxicants to human body

? Toxicant- chemical with adverse human health

--- Content provided by‌ FirstRanker.com ---

effects

? Acute toxicity

? Adverse effects occur within a short period after

--- Content provided by‍ FirstRanker.com ---


exposure to toxin

? Chronic toxicity

--- Content provided by FirstRanker.com ---

? Adverse effects occur some time after exposure,

or after prolonged exposure to toxin

? Symptoms often mimic other diseases- hard to

--- Content provided by FirstRanker.com ---


assess source

Children and Chemical Exposure

--- Content provided by​ FirstRanker.com ---

? Children are more susceptible to chemicals

? Weigh less than adults

? Bodies are stil developing

--- Content provided by​ FirstRanker.com ---


? Play on floors and lawns

? Exposed to cleaning products and pesticides

--- Content provided by FirstRanker.com ---

? Put things into their mouths
Exposure Of Chemical Mixtures

? Generally humans body is exposed to chemical

--- Content provided by‍ FirstRanker.com ---

mixtures

? Ex: automobile exhaust

? Chemical Mixtures interact by

--- Content provided by‌ FirstRanker.com ---


? Additivity

? Synergy

--- Content provided by‍ FirstRanker.com ---

? Antagonism

Risk Assessment

? Risk- probability that a particular adverse effect wil

--- Content provided by‍ FirstRanker.com ---


result from some exposure or condition

? We assess risk daily with four steps:

--- Content provided by FirstRanker.com ---

1. Hazard identification

2. Dose response assessment

3. Exposure assessment

--- Content provided by⁠ FirstRanker.com ---


4. Risk characterization


Environmental Hazards

--- Content provided by⁠ FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by‌ FirstRanker.com ---


Composition of Atmosphere

? Composition of gases in

--- Content provided by FirstRanker.com ---

an atmosphere is not

uniform.

? Lighter gases tend to rise

--- Content provided by‍ FirstRanker.com ---


to top.

Gases are measured in ppm volume (?L/L), which is

--- Content provided by⁠ FirstRanker.com ---

directly proportional to mole fraction.
Outer Atmosphere

? Sun emits radiation

--- Content provided by​ FirstRanker.com ---

across an

electromagnetic

o

--- Content provided by⁠ FirstRanker.com ---

f

p
h
o

--- Content provided by⁠ FirstRanker.com ---

t
o
n
s

--- Content provided by​ FirstRanker.com ---

spectrum.

umber

? Light in an ultraviolet

--- Content provided by⁠ FirstRanker.com ---


N

region has enough

--- Content provided by⁠ FirstRanker.com ---

energy to break

chemical bonds.

Wavelength, m

--- Content provided by FirstRanker.com ---


Energy

Ozone

--- Content provided by FirstRanker.com ---

? Ozone absorbs much of radiation between 240 and 310

nm.

? It forms from reaction of molecular oxygen with an oxygen

--- Content provided by​ FirstRanker.com ---


atoms produced in upper atmosphere by

photodissociation (< 242 nm).

--- Content provided by‍ FirstRanker.com ---

O + O2 O3
Ozone Depletion

In 1974 Rowland and Molina (Nobel Prize, 1995)

--- Content provided by FirstRanker.com ---

discovered that chlorine from chlorofluorocarbons

(CFCs) may be depleting the supply of ozone in the

upper atmosphere.

--- Content provided by FirstRanker.com ---


Troposphere

Although Troposphere is made up almost entirely of

--- Content provided by‌ FirstRanker.com ---

nitrogen and oxygen, other gases present in relatively small

amounts still have a profound effect on troposphere.
Radiation

--- Content provided by‌ FirstRanker.com ---

Aurora

Formed {Atmosphere is first

here

--- Content provided by FirstRanker.com ---


line of defense against

radiation from Sun.

--- Content provided by​ FirstRanker.com ---

Chlorofluorocarbons

CFCs were used for years as aerosol

propellants and refrigerants.

--- Content provided by‍ FirstRanker.com ---


Mostly = CFCl3, CF2Cl2.

They are not water soluble (so they do not

--- Content provided by‍ FirstRanker.com ---

get washed out of the atmosphere by rain)

and are quite unreactive (so they are not

degraded naturally).

--- Content provided by⁠ FirstRanker.com ---

Water Vapor and Carbon Dioxide

? Gases in an atmosphere form an insulating blanket that

causes the Earth's thermal consistency.

--- Content provided by FirstRanker.com ---


? Two of the most important such gases are carbon

dioxide and water vapor.

--- Content provided by‍ FirstRanker.com ---

Water Vapor and Carbon Dioxide

? This blanketing effect is

known as the "greenhouse

--- Content provided by‍ FirstRanker.com ---


effect."

? Water vapor, with its high

--- Content provided by⁠ FirstRanker.com ---

specific heat, is a major

factor in this moderating

effect.

--- Content provided by‌ FirstRanker.com ---


? But increasing levels of CO2

in an atmosphere is causing

--- Content provided by⁠ FirstRanker.com ---

an increase in global

temperatures.


--- Content provided by‍ FirstRanker.com ---

Sulfur

? Sulfur dioxide is a by-product of burning of coal or oil.

? It reacts with moisture in air to form sulfuric acid.

--- Content provided by FirstRanker.com ---


? It is primarily responsible for acid rain.

Carbon Monoxide

--- Content provided by‍ FirstRanker.com ---

? Carbon monoxide binds

preferentially to the iron

in red blood cells.

--- Content provided by‍ FirstRanker.com ---


? Exposure to CO can

lower O2 levels to the

--- Content provided by‍ FirstRanker.com ---

point of causing loss of

consciousness and death.


--- Content provided by‌ FirstRanker.com ---

Nitrogen Oxides

? What we recognize as

smog, that brownish gas

--- Content provided by FirstRanker.com ---


that hangs above large

cities like Los Angeles, is

--- Content provided by⁠ FirstRanker.com ---

primarily nitrogen

dioxide, NO2.

? It forms from the

--- Content provided by‌ FirstRanker.com ---


oxidation of nitric oxide,

NO, a component of car

--- Content provided by⁠ FirstRanker.com ---

exhaust.


Photochemical Smog

--- Content provided by‌ FirstRanker.com ---

Smog also contains ozone, carbon monoxide,

hydrocarbons, and particles.


--- Content provided by‍ FirstRanker.com ---

Effect of Photochemical Smog on

Human Health


--- Content provided by⁠ FirstRanker.com ---






--- Content provided by‍ FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by‍ FirstRanker.com ---






--- Content provided by​ FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by FirstRanker.com ---






--- Content provided by​ FirstRanker.com ---






--- Content provided by FirstRanker.com ---



Effects Of Water Pol ution


--- Content provided by‍ FirstRanker.com ---






--- Content provided by‌ FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by​ FirstRanker.com ---




Shocking side effects of Earphones

--- Content provided by​ FirstRanker.com ---

To Brain and Ears!

? TINNITUS. [Noise in ear]. . .

? HYPERACUSIS. This is an increased sensitivity to

--- Content provided by FirstRanker.com ---


normal environment sounds.

? SEVERE EAR INFECTION. It is usual y unavoidable

--- Content provided by‍ FirstRanker.com ---

that people share earphones. . .

? LOSS OF HEARING. . .

? AFFECTS YOUR BRAIN. . .

--- Content provided by‌ FirstRanker.com ---


? EAR PAIN. . .

? LOSS OF CONNECTION WITH REALITY. . .

--- Content provided by⁠ FirstRanker.com ---

? LEARNING DISABILITIES.

Research findings

Sound's volume by 6 to 9 decibels

--- Content provided by‍ FirstRanker.com ---


? Loud music played on earphones causes hearing

loss by having a similar effect on nerves as

--- Content provided by FirstRanker.com ---

multiple sclerosis,

? Research shows noise levels above 110 decibels

strip insulation from nerve fibers carrying signals

--- Content provided by‍ FirstRanker.com ---


from the ear to the brain.



--- Content provided by‍ FirstRanker.com ---






--- Content provided by‍ FirstRanker.com ---






--- Content provided by FirstRanker.com ---






--- Content provided by⁠ FirstRanker.com ---






--- Content provided by​ FirstRanker.com ---



Human Responsibilities To Maintain

Healthy Environment

--- Content provided by‍ FirstRanker.com ---


? Use Sense, time and Energy for Significance and

Health

--- Content provided by‍ FirstRanker.com ---

? Be Monitor,maintainer,Constructor

? Never be Destructor

? Do sensible environmental friendly acts which

--- Content provided by⁠ FirstRanker.com ---


control and prevent pollution



--- Content provided by FirstRanker.com ---

Factors For Quality Of Health

? Intentions and Actions= Behavior (Sleep Cycle)

? Nutrition (Food Cycle)

--- Content provided by‍ FirstRanker.com ---


? Environment