Download RGUHS B.Pharm 2018 January 4th Year 2623 Pharmacy Practice II Rs 3 Question Paper

Download RGUHS (Rajiv Gandhi University of Health Sciences) B.Pharm (Bachelor of Pharmacy) 2018 January 4th Year 2623 Pharmacy Practice II Rs 3 Previous Question Paper


Rajiv Gandhi University of Health Sciences, Karnataka

IV Year B.Pharm Degree Examination - JAN-2019

Time: Three Hours



Max. Marks: 70 Marks

PHARMACY PRACTICE ? II (RS-3)

a. Pharmacokinetics and Therapeutic Drug Monitoring

Q.P. CODE: 2623

Your answers should be specific to the questions asked

Draw neat labeled diagrams wherever necessary

LONG ESSAYS (Answer any Two)

2 x 10 = 20 Marks

1.

Describe in detail about estimation of elimination kinetics of a drug by urinary excretion data.

2.

Write a note on two-compartment open model after IV bolus administration.

3.

Define protein binding of drugs. Discuss the kinetics involved in protein binding

SHORT ESSAYS (Answer any Six)

6 x 5 = 30 Marks

4.

Differentiate between clearance and extraction ratio. Describe the significance of hepatic
clearance.

5.

Describe AUC and its determination

6.

Write a note on mono exponential decline

7.

Physiological factors related to protein binding

8.

Dosage adjustment in hepatic and renal impairment

9.

What is dosage regimen? Write the principle underlying in dosage regimen design

10.

Write a note on drug dosing in pediatrics.

11.

TDM of Methotrexate

SHORT ANSWERS

10 x 2 = 20 Marks

12.

Write any two applications of TDM

13.

Organization of TDM

14.

Non-renal clearance

15.

Advantages of compartment model

16.

Name the factors affecting drug distribution

17.

Concept of loading dose and its significance

18.

Biological half life

19.

Define pharmacokinetics

20.

Cmax and Tmax

21.

What is drug accumulation?

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This post was last modified on 06 January 2023