Max. Marks: 70 Marks
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Advanced Industrial Pharmacy
(RS ? 4)
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Q.P. CODE: 2646Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
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LONG ESSAYS (Answer any Two)
2 x 10 = 20 Marks
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1.Write the concept of controlled drug delivery systems. Explain the approaches for the
Controlled release formulations based on dissolution.
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2.Explain how the development of master formula records and batch manufacturing records play
an important role in pilot plant scale up studies.
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3.Define validation. Explain the significance of validation in pharmaceutical operations with
respect to mixing and compression.
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SHORT ESSAYS (Answer any Six)6 x 5 = 30 Marks
4.
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Define solid dispersions. Explain any one method of preparation of solid dispersions.
5.
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Explain concept, advantages and disadvantages of nanoparticles.6.
Explain concept, advantages and disadvantages of implants.
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7.
Explain glass as the container for the pharmaceutical packaging.
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8.Explain the salient features of USFDA with respect to manufacture of finished products.
9.
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Define and explain average, mean, median and mode.
10.
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Define biostatistics. What is the significance of biostatistics in pharmacy?11.
Define bioavailability. Explain how the bioavailability of poorly soluble drugs can be improved.
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SHORT ANSWERS
10 x 2 = 20 Marks
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12.Define half life and protein binding.
13.
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What are the ideal requirements for ocular drug delivery systems?
14.
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What is technology transfer?15.
Name different types of validation.
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16.
What are the advantages and disadvantages of plastic as the pharmaceutical packaging
material?
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17.
What is cGMP? Write the significance of implementation of cGMP?
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18.What are the objectives of TGA guidelines?
19.
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Define standard deviation.
20.
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What are the efficacy guidelines as per ICH?21.
What are the benefits of QbD?
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