Download MBBS First Year Biochemistry Paper I MCQs 2022 Question Paper

[MBBS 0222]

M.B.B.S. DEGREE EXAMINATION

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(For the candidates admitted from the Academic Year 2019-2020)

FIRST YEAR

PAPER I – BIOCHEMISTRY

MULTIPLE CHOICE QUESTIONS

Time: 30 Minutes Q.P. Code: 526055 Maximum: 20 Marks

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Answer All Questions

Choose one correct answer in the box provided in the Answer Script. No overwriting should be done.

III. Multiple Choice Questions: (20 x 1 = 20)

1. Which of the following is a lipotropic factor?
   1. Sphingomyelin.
   2. Choline.

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   3. Cardiolipin.
   4. Orotic acid
2. Co enzyme A is derived from which of the following Vitamin ?
   1. Niacin.
   2. Biotin.

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   3. Pantothenic acid
   4. Cobalamin.
3. Pernicious anemia may result due to the dietary deficiency of which of the following vitamin ?
   1. Folic acid
   2. Pyridoxine.

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   3. Pantothenic acid
   4. Cobalamin.
4. In premature newborns, the deficiency of which lipid is associated with respiratory distress syndrome
   1. Phosphatidyl choline.
   2. Phosphatidyl ethanolamine.

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   3. Phosphatidyl inositol.
   4. Phosphatidyl glycerol.
5. Aspirin inhibits the activity of the enzyme
   1. Lipoxygenase
   2. Cyclooxygenase

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   3. Phospholipase A1
   4. Phospholipase A2
6. Pulses are deficient in
   1. Lysine
   2. Threonine

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   3. Methionine
   4. Tryptophan
7. Niemann-pick disease is due to defect in the which enzyme ?
   1. Beta-glucosidase
   2. Sphingomyelinase

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   3. Beta-galactosidase
   4. Hexosaminidase A
8. Normal plasma cholesterol level is
   1. 40 - 60 mg/100 ml.
   2. 70 - 110 mg/100 ml.

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   3. 120 - 150 mg/100 ml.
   4. 150 - 200 mg/100 ml.
9. The following vitamins has antioxidant property except
   1. Vitamin C.
   2. Vitamin E.

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   3. Vitamin A.
   4. Vitamin K.
10. All of the following are substrates for gluconeogenesis except
    1. Alanine.
    2. Leucine.

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    3. Glycerol.
    4. Methionine.
11. In TCA cycle, substrate level phosphorylation takes place in
    1. Alpha ketoglutarate to succinyl CoA.
    2. Succinyl CoA to succinate.

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    3. Succinate to fumarate.
    4. Oxaloacetate to citrate.
12. Renal threshold for glucose is
    1. 80 mg%
    2. 120 mg %

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    3. 180 mg%
    4. 200 mg %
13. The product of oxidation of odd chain fatty acids is
    1. Aceto Acetyl CoA
    2. Malonyl CoA

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    3. Propionyl CoA
    4. Fumaryl CoA
14. Rate limiting step in Cholesterol synthesis is
    1. HMG CoA synthase.
    2. HMG CoA lyase.

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    3. HMG CoA reductase.
    4. Squalene synthase.
15. NADPH is required for
    1. Gluconeogenesis.
    2. HMP Shunt.

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    3. Glycolysis.
    4. Fatty acid Synthesis.
16. Glycogen synthesis is increased by
    1. Cortisone.
    2. Insulin.

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    3. Glucagon.
    4. Epinephrine.
17. An example of competitive inhibition of an enzyme is
    1. Succinate dehydrogenase by malonate.
    2. Cytochrome oxidase by cyanide.

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    3. Hexokinase by glucose-6-phosphate.
    4. Phosphofructokinase by citrate.
18. In a cell, digestive enzymes mostly occurs in
    1. Mitochondria.
    2. Lysosomes.

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    3. Ribosome.
    4. Golgi apparatus.
19. Net yield of ATP from one molecule of palmitic acid is
    1. 8 ATP
    2. 32 ATP

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    3. 38 ATP
    4. 106 ATP
20. Which factor decreases the affinity of hemoglobin for oxygen binding ?
    1. An increase in 2,3 BPG level in blood
    2. A rise in pH

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    3. Oxidation of iron to ferric state in one subunit
    4. Vomiting

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