Blood Storage in blood bank
Who can be a blood donor
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Complications of Blood transfusions (transfusion reactions)
Blood components
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What is blood transfusion
The transfer of blood or blood components from one person (the donor)
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into the bloodstream of another person (the recipient)Blood Typing
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Cross MatchingCross Matching is a procedure performed prior to a blood transfusion to detect
incompatibilities between the donor and recipient.
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Cross Matching
Indication of blood transfusion
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Many times, blood transfusion might not be without hazards, so the risk should be
weighed out against benefit.
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The dictum is - TO USE BLOOD PRODUCTS ONLY WHEN NO OTHER ALTERNATIVE IS LEFTBlood Donation : Who Can Give Blood?
Basic Eligibility Guidelines
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Age:
Weight:
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Hb:Serum Transmitted Disease patient :
Vaccintion:
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High Blood Pressure:
Diabetes:
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Cold and Flu:Diet:
Tattoos and Piercing:
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Blood Transfusion Therapy
Storage of blood
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Blood should be tested for Blood/Serum
Transmitted Diseases (STDs) before storage
Storage of blood
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CPDA-1
Tri sodium citrate
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26.35(g)
Citric acid (g)
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3.27
Dextrose (g)
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31.90Monobasic sodium
2.22
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phosphate (g)
Adenine (g)
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0.27Distilled water (ml)
1000
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Preservative (ml) /
14
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100ml bloodStorage at 2-6 ?C
Hazards of blood transfusion
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Transfusion reaction
Due to mismatching/hemolytic
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Other than mismatching
(Agglutination/Immunologic reaction)
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Hemolytic Transfusion Reactions (HTR)
Hemolytic Transfusion Reactions (HTR)
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Non-Hemolytic Transfusion Reactions (NHTR)Mild Allergic Reactions
Anaphylactic Shock
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& Non hemolytic
Spread of Serum Transmitted Disease
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Transfusion of Blood ComponentsTransfusion of `Blood Components' is ?
When, specific portion or fraction of blood that is lacking in a patient is
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transfused.
Advantages of blood component therapy
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Avoids the risk of sensitizing the patients to other blood components.Provides optimal therapeutic benefit while reducing risk of volume overload.
Increases availability of needed blood products to larger population.
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Thus it is a safe and low risk procedure
Self Assessment
Critical Thinking Questions
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1. Following a motor vehicle accident, a patient is rushed to the emergency department with multiple traumatic injuries,
causing severe bleeding. The patient's condition is critical, and there is no time for determining his blood type. What
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type of blood is transfused, and why?2. In preparation for a scheduled surgery, a patient visits the hospital lab for a blood draw. The technician collects a blood
sample and performs a test to determine its type. She places a sample of the patient's blood in two wel s. To the first wel
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she adds anti-A antibody. To the second she adds anti-B antibody. Both samples visibly agglutinate. Has the technician
made an error, or is this a normal response? If normal, what blood type does this indicate?
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Self Assessment1. The process in which antibodies attach to antigens, causing the formation of masses of linked cells, is cal ed-
A. sensitization
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B. coagulation
C. agglutination
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D. hemolysis2. People with type O blood group -
A. have both antigens A and B on their erythrocytes
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B. lack both antigens A and B on their erythrocytes
C. have neither anti-A nor anti-B antibodies circulating in their blood plasma
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D. are considered universal recipients3. Hemolytic disease of the newborn is a risk during a subsequent pregnancy in which:
A. a type AB mother is carrying a type O fetus
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B. a type O mother is carrying a type AB fetus
C. a Rh+ mother is carrying an Rh- fetus
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D. a Rh- mother is carrying a second Rh+ fetusThank you