SHORT BOWEL SYNDROME
The decreased absorptive
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ability of intestines- either
due to short length or
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functional reduction due todiseases- jeopardizing
survival.
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Due to:
1. Congenital gut defects
2. Malabsorptive diseases
3. Surgical removal of long
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segments of intestines
Normal bowel length
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Neonatal: 200-300 cmChildren:
Adult : 700-800 cm
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SHORT BOWEL SYNDROME
Various definitions:
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1. 50% or more of the small bowel resected.2. When Ileocaecal valve is present: 25-30 cm
When ileocaecal valve is absent: 40cm
If Ileocaecal valve is lost,
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transit time is faster and loss
of fluid and nutrients is greater.
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ETIOLOGY
Necrotising enterocolitis (35%)
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Intestinal atresias (25%)
Gastroschisis (18%)
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Malrotation with midgutvolvulus (14%)
Long segment Hirschsprung's(2%)
Others (6%)
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NECROTISING ENTEROCOLITIS (35%)
One of the most common gastrointestinal emergencies in the
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newborn infant.Premature neonates that results in inflammation and bacterial
invasion of the bowel wall.
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INTESTINAL ATRESIAS (25%)
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Congenital complete blockage or obstruction anywhere in theintestine.
Duodenal, jejunal, ileal- usually treated by resection and end
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to end anastomosis.
Some develop severe
disruption- large part atretic.
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In about 10%- lack dorsal
mesentery and assume a
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GASTROSCHISIS (18%)
Fetal bowel eviscerates through a narrow
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abdominal wall defect.
Exposed to amniotic fluid;
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associated with other malformations;tight abdominal compartment.
MALROTATION WITH MIDGUT VOLVULUS
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MANAGEMENT
Requires a multi-disciplinary approach that includes
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- neonatologists,
- gastroenterologists,
- surgeons,
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- nutritionists,- pharmacists,
- stomal therapists,
- nurses, etc.
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SURGICAL MANAGEMENT1. Bowel conservation at initial presentation.
2. Bowel lengthening surgeries.
3. Intestinal transplantation.
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BOWEL LENGTHENING SURGERIES
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Longitudinal intestinal
lengthening and tailoring
(LILT) procedure(BIANCHI 1980).
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- Doubles bowel length.- Improves peristalsis.
- Anastomotic leak
- Anastomotic stenosis
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- Fistula formation- Sepsis
BOWEL LENGTHENING SURGERIES
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Serial Transverse Enteroplasty(STEP) ? creates a longer and
narrower intestine.
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- - Staple line leak
- Hematoma
- Bowel obstruction
- Abscess
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INTESTINAL TRANSPLANTATION
Last resort in irreversible liver and intestinal failure.
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Types :
1.
Isolated intestine
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2.
Combined intestine and liver
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3.Multivisceral
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INTESTINAL TRANSPLANTATION
Complications
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- Acute rejection,- Infection,
- Graft-versus-host disease, and
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- Post-transplant lympho-proliferative disease.