HEALTH SCIENCES
MBBS FIRST YEAR EXAMINATIONS:
NOVEMBER, 2023
WARANGAL, TELANGANA STATE-506002
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PHYSIOLOGY (New Regulation)PAPER - I
Time: 3 Hours
Max Marks: 100
Note: Answer all questions
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Draw diagrams whenever necessary with Black Ball pointpen/HB pencil/any dark Colour pencil
Multiple Choice Questions:
1. Which statement about feedback control systems is
incorrect 10 X 1 = 10
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a) Most control systems of the body act by negativefeedback
c) Generation of nerve action potentials involves
positive feedback
b) Positive feedback usually promotes stability in a
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systemd) Feed-forward control is important in regulating
muscle activity
2. Gap junctions
a) Maintain cellular polarity
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c) Have corresponding connections between cells
b) Occur at the apices of cells
d) Help in transport of polypeptides molecules
3. P50 or the P02 which produces 50% saturation of
arterial haemoglobin is
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a) 30 mm Hgc) 28 mm Hg
b) 26 mm Hg.
d) 22 mm Hg
4. Central pattern generator:
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a) Pre-Botzinger complexc) Nucleus ambiguus
b) Nucleus of tractus solitarius
d) Retrofacialis
5. Which part of the ECG corresponds to ventricular
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repolarization?a) The P wave
c) The T wave.
b) The QRS duration
d) The U wave
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6. Duration of cardiac cycle at the rate of 100beats/min isa) 0.8sec
c) 1 sec
b) 0.6sec
d) 0.2sec
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7. Renin is secreted bya) Cells in the macula densa.
c) Cells in the distal tubules
b) Cells in the proximal tubules
d) Juxtaglomerular cells
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8. Small intestinal motility is increased by:a) Gastrin.
c) Glucagon
b) Secretin
d) GIP
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9. Trypsin inhibitor:a) Inhibits the action of pancreatic enzymes in the
lumen of the duodenum
c) In excess causes acute pancreatitis
b) Inhibits activation of trypsin in the pancreas.
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d) Is produced by enterocytes10. In which part of the cell does the inborn errors of
metabolism characterized by accumulation of substrate in
excess in various organ cells due to defective functioning
a) Lysosome
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c) Golgi Apparatusb) Mitochondria
d) Nucleus
Essay/ Long Answer Questions:
11. A 23-year-old male met with a road traffic accident
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brought to the Emergency department with restlessnessand irritability. On examination, patient had rapid thready
pulse, hypotension, rapid shallow breathing and oliguria.
2 X 15-30
a) Identify the condition.
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b) Define shock and its types.c) State about cardiac output in this patient.
(2+3+3+7)
d) Discuss in detail about factors regulating cardiac
output.
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12. A 22-year-old female attending to outpatientdepartment complains of tiredness and easy fatiguability
even with mild exertion. On examination, patient's skin
and mucous membranes appear pale. Patient's peripheral
smear showed decrease in the size of RBC with increased
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central pallor. Lab report shows decreased MCV,decreased MCH and decreased MCHC.
a) Identify the above condition.
b) Discuss in detail about stages the of Erythropoiesis
c) Describe the regulation of Erythropoiesis.
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d) Add a note on osmotic fragility of RBC's.(2+5+5+3)
Short Answer Questions:
13. Describe the factors influencing GFR. 7 X 6 = 42
14. Name the different body fluid compartments. Give the
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composition of extracellular and intracellular fluidMention the methods to measure ECF.
15. Write composition and explain the functions of
Pancreatic juice
16. Write the movements of small intestine.
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17. Enumerate the factors regulating ChemicalRespiration
18. Define Asphyxia, types and stages of Asphyxia.
19. Describe professional qualities of a physician.
Very Short Answer Questions:
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20. Heart block. 6 X 3 = 1821. Mismatched blood transfusion reaction.
22. Describe the physiological significance of Pulmonary
surfactant.
23. Loop of Henle - filtration fraction.
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24. Cystometrogram.25. Endocytosis.