Madhya Pradesh Medical Science University,
Jabalpur
MBBS First Professional Examination Nov-2023
Subject- Biochemistry
Paper-I
Maximum Marks :100
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
written strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1. (a) 2.
f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Q1. Total MCQs: 10 10 x 1 = 10
(a) heparin (b) hyaluronic acid (c) dermatan sulfate (d)
cellulose
2. Nyctalopia is
(a) drying of eyes (b) destruction of cornea (c) blindness
3. Which is the most common amino acid present in
collagen
(a) lysine (b) glycine (c) threonine (d) proline
4. The most important clinical importance of the BMR is
(a) thyroid dysfunction (b) gastrointestinal disturbances
(c) liver ailments (d) nephritis
5. Vegetarians, who do not consume milk should take
daily
6. During respiratory burst, all of the following reactive
oxygen species (ROS) are formed, EXCEPT
(a) superoxide (b) hydrogen peroxide (c) nitric oxide
(d) hydroxyl radical
(a) acrodermatitis enteropathy (b) wilson's disease (c)
xeroderma pigmentosum (d) menke's disease
8. Which of the disease listed below is a lysosomal
storage disease
pompe's disease (d) leber's neuropathy
9. 25-hydroxylation of vitamin D occurs in
(a) skin (b) liver (c) kidneys (d) intestinal mucosa
10. Vitamin C enhances intestinal absorption of
Q2. Long Answer Questions 2 x 20 = 40
a. Define enzymes with classification. Write different
types of enzymes inhibition with suitable examples.
Explain isoenzymes with examples. Indicate the
b. A 50-year-old obese lady complains of excessive thirst
and hunger, with increased urination. On physical
examination she appeared normal. Her laboratory report
showed the following findings; random plasma glucose
glucose strips. Her fasting and postprandial plasma
glucose levels were 130 mg/dL and 195 mg/dL
respectively
i. What is your diagnosis and write the biochemical
ii. Which biochemical investigations will help in
diagnosis of the disease
iii. What are the characteristic clinical features of the
disorder
Q3. Brief Answer Questions 6 x 05 = 30
a. What does it mean to be a doctor
b. Regulation of plasma calcium level
c. One year old female child with low socio-economic
appearance. No edema is present
i. Identify the condition
ii. What is the difference between marasmus and
kwashiorkor
d. Explain cholesterol metabolism
e. Describe electron transport chain. Write uncouplers
with their significance
f. Write the sources, RDA, and deficiency manifestations
Q4. Short Answer Questions 10 x 2 = 20
a. Enumerate biologically important peptides
b. Enumerate antioxidant enzymes and minerals
c. Nitrogen balance
e. Alkaptonuria
f. Well labeled diagram of cell membrane
g. Define classify carbohydrates
h. Define detoxification with its examples
j. Wilson's disease manifestations
***
Jabalpur
MBBS First Professional Examination Nov-2023
Subject- Biochemistry
Paper-I
--- Content provided by FirstRanker.com ---
Time: 3:00 HoursMaximum Marks :100
Instructions:
a) All questions are compulsory
b) Draw diagrams wherever necessary
--- Content provided by FirstRanker.com ---
c) Answers of Questions and Sub-questions must bewritten strictly according to serial order of question paper.
d) MCQ has to be answered in theory answer book
e) Please write MCQ answer neatly and in serial order
with black or blue pen in brackets; for example: - 1. (a) 2.
--- Content provided by FirstRanker.com ---
(c)f) MCQ has to be answered only once, any kind of
repetition or cutting or erasing or whitener will be
considered as malpractice, such answers will not be
counted in marks and action will be taken according to
--- Content provided by FirstRanker.com ---
UFM rules of university.g) Subjective answer should be answered in up to 30
words per marks. For example, if a question having 2
marks should answered in up to 60 marks.
Q1. Total MCQs: 10 10 x 1 = 10
--- Content provided by FirstRanker.com ---
1. A homopolysaccharide among the following is(a) heparin (b) hyaluronic acid (c) dermatan sulfate (d)
cellulose
2. Nyctalopia is
(a) drying of eyes (b) destruction of cornea (c) blindness
--- Content provided by FirstRanker.com ---
(d) inability to see in dim light3. Which is the most common amino acid present in
collagen
(a) lysine (b) glycine (c) threonine (d) proline
4. The most important clinical importance of the BMR is
--- Content provided by FirstRanker.com ---
that it is an indicator of(a) thyroid dysfunction (b) gastrointestinal disturbances
(c) liver ailments (d) nephritis
5. Vegetarians, who do not consume milk should take
daily
--- Content provided by FirstRanker.com ---
(a) vit. B1 (b) vit. B6 (c) vit. B12 (d) vit. C6. During respiratory burst, all of the following reactive
oxygen species (ROS) are formed, EXCEPT
(a) superoxide (b) hydrogen peroxide (c) nitric oxide
(d) hydroxyl radical
--- Content provided by FirstRanker.com ---
7. Copper deficiency occurs commonly in(a) acrodermatitis enteropathy (b) wilson's disease (c)
xeroderma pigmentosum (d) menke's disease
8. Which of the disease listed below is a lysosomal
storage disease
--- Content provided by FirstRanker.com ---
(a) Zellweger syndrome (b) inclusion cell bodies (c)pompe's disease (d) leber's neuropathy
9. 25-hydroxylation of vitamin D occurs in
(a) skin (b) liver (c) kidneys (d) intestinal mucosa
10. Vitamin C enhances intestinal absorption of
--- Content provided by FirstRanker.com ---
(a) potassium (b) iodine (c) iron (d) none of the aboveQ2. Long Answer Questions 2 x 20 = 40
a. Define enzymes with classification. Write different
types of enzymes inhibition with suitable examples.
Explain isoenzymes with examples. Indicate the
--- Content provided by FirstRanker.com ---
importance of enzyme studies in myocardial infarction.b. A 50-year-old obese lady complains of excessive thirst
and hunger, with increased urination. On physical
examination she appeared normal. Her laboratory report
showed the following findings; random plasma glucose
--- Content provided by FirstRanker.com ---
level: 250 mg/dL. Urine was positive for glucose withglucose strips. Her fasting and postprandial plasma
glucose levels were 130 mg/dL and 195 mg/dL
respectively
i. What is your diagnosis and write the biochemical
--- Content provided by FirstRanker.com ---
basis of the disorderii. Which biochemical investigations will help in
diagnosis of the disease
iii. What are the characteristic clinical features of the
disorder
--- Content provided by FirstRanker.com ---
iv. Mechanism of action of responsible hormoneQ3. Brief Answer Questions 6 x 05 = 30
a. What does it mean to be a doctor
b. Regulation of plasma calcium level
c. One year old female child with low socio-economic
--- Content provided by FirstRanker.com ---
status comes to OPD with retarded growth and emaciatedappearance. No edema is present
i. Identify the condition
ii. What is the difference between marasmus and
kwashiorkor
--- Content provided by FirstRanker.com ---
iii. What is the cause of emaciated appearanced. Explain cholesterol metabolism
e. Describe electron transport chain. Write uncouplers
with their significance
f. Write the sources, RDA, and deficiency manifestations
--- Content provided by FirstRanker.com ---
of vitamin AQ4. Short Answer Questions 10 x 2 = 20
a. Enumerate biologically important peptides
b. Enumerate antioxidant enzymes and minerals
c. Nitrogen balance
--- Content provided by FirstRanker.com ---
d. Biochemical importance of serotonine. Alkaptonuria
f. Well labeled diagram of cell membrane
g. Define classify carbohydrates
h. Define detoxification with its examples
--- Content provided by FirstRanker.com ---
i. Enumerate essential fatty acidsj. Wilson's disease manifestations
***